Powered by


                    Home  |  Forums  |  Humor  |  Advertising  |  Contact
   Ask a Doctor

   News via RSS






   Forum Archives





















   Primary Care






   Other Sections


   Research Tools

   Medical Tutorials

   Medical Software




Back to Cardiology Drug index

Back to Beta-2 receptor agonists

Name: Dobutamine Hydrochloride

Pregnancy Category C

Drug classes

  • Sympathomimetic drug
  • Beta-1 adrenergic agonist

Therapeutic actions

Positive inotropic effects are mediated by beta-1 adrenergic receptors in the heart; increases the force of mycocardial contraction with relatively minor effects on heart rate, arrhythmogenesis; has minor effects on blood vessels.


For inotropic support in the short-term treatment of adults with cardiac decompensation due to depressed contractility, resulting from either organic heart disease or from cardiac surgical procedures Investigational use in children with congenital heart disease undergoing diagnostic cardiac catheterization, to augment cardiovascular function


Contraindicated in the presence of IHSS; hypovolemia (dobutamine is not a substitute for blood, plasma, fluids, electrolytes, which should be restored promptly when loss has occurred and in any case before treatment with dobutamine); acute myocardial infarction (may increase the size of an infarct by intensifying ischemia); general anesthesia with halogenated hydrocarbons or cyclopropane, which sensitize the myocardium to catecholamines.

Use caution in the presence of diabetes, lactation.

Adverse effects

  • CNS: Headache
  • GI: Nausea
  • CV: Increase in heart rate, increase in systolic blood pressure, increase in ventricular ectopic beats (PVCs), anginal pain, palpitations, shortness of breath
advertisement.gif (61x7 -- 0 bytes)

Are you a doctor or a nurse?

Do you want to join the Doctors Lounge online medical community?

Participate in editorial activities (publish, peer review, edit) and give a helping hand to the largest online community of patients.

Click on the link below to see the requirements:

Doctors Lounge Membership Application


 advertisement.gif (61x7 -- 0 bytes)



We subscribe to the HONcode principles of the HON Foundation. Click to verify.
We subscribe to the HONcode principles. Verify here

Privacy Statement | Terms & Conditions | Editorial Board | About us
Copyright 2001-2012 DoctorsLounge. All rights reserved.