Advertisement
 

doctorslounge.com

 
Powered by
Careerbuilder

 

                    Home  |  Forums  |  Humor  |  Advertising  |  Contact
   Ask a Doctor

   News via RSS

   Newsletter

   Cardiology

   News

   Conferences

   CME

   Forum Archives

   Diseases

   Symptoms

   Labs

   Procedures

   Drugs

   Links
   Specialties

   Cardiology

   Dermatology

   Endocrinology

   Fertility

   Gastroenterology

   Gynecology

   Hematology

   Infections

   Nephrology

   Neurology

   Oncology

   Orthopedics

   Pediatrics

   Pharmacy

   Primary Care

   Psychiatry

   Pulmonology

   Rheumatology

   Surgery

   Urology

   Other Sections

   Membership

   Research Tools

   Medical Tutorials

   Medical Software

 Headlines:

 
 

 

Back to Cardiology Drug index

Back to Beta-2 receptor agonists

Name: Dopamine Hydrochloride

Pregnancy Category C

Drug classes

  • Sympathomimetic drug
  • Alpha-adrenergic agonist
  • Beta-1 adrenergic agonist
  • Dopaminergic agonist

Therapeutic actions

Drug acts directly and by the release of norepinephrine from sympathetic nerve terminals; dopaminergic receptors mediate dilation of vessels in the renal and splanchnic beds, which maintains renal perfusion and function; alpha receptors, which are activated by higher doses of dopamine, mediate vasoconstriction, which can override the vasodilating effects; beta-1 receptors mediate a positive inotropic effect on the  heart.

Indications

Correction of hemodynamic imbalances present in the shock syndrome due to MI, trauma, endotoxic septicemia, open heart surgery, renal failure, and chronic cardiac decompensation in congestive failure

Contraindications/cautions

Contraindicated in the presence of pheochromocytoma, tachyarrhythmias, ventricular fibrillation, hypovolemia (dopamine is not a substitute for blood, plasma, fluids, electrolytes, which should be restored promptly when loss has occurred), general anesthesia with halogenated hydrocarbons or cyclopropane, which sensitize the myocardium to catecholamines.

Use caution in the presence of atherosclerosis, arterial embolism, Reynaud's disease, cold injury, frostbite, diabetic endarteritis, Buerger's disease (closely monitor skin color and temperature of the extremities).

Adverse effects

  • GI: Nausea, vomiting
  • CV: Ectopic beats, tachycardia, anginal pain, palpitations, hypotension, vasoconstriction, dyspnea, bradycardia, hypertension, widened QRS
  • Other: Headache, piloerection, azotemia, gangrene with prolonged use
advertisement.gif (61x7 -- 0 bytes)
 

Are you a doctor or a nurse?

Do you want to join the Doctors Lounge online medical community?

Participate in editorial activities (publish, peer review, edit) and give a helping hand to the largest online community of patients.

Click on the link below to see the requirements:

Doctors Lounge Membership Application


 

 advertisement.gif (61x7 -- 0 bytes)

 

 



We subscribe to the HONcode principles of the HON Foundation. Click to verify.
We subscribe to the HONcode principles. Verify here

Privacy Statement | Terms & Conditions | Editorial Board | About us
Copyright 2001-2012 DoctorsLounge. All rights reserved.