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Back to Cardiology Drug index
Name: Triamterene
Pregnancy Category B
Drug classes
- Potassium-sparing diuretic
Therapeutic actions
Inhibits sodium reabsorption in the renal distal tubule, causing loss
of
sodium and water and retention of potassium.
Indications
Edema associated with CHF, nephrotic syndrome, hepatic cirrhosis;
steroid-induced edema, edema from secondary hyperaldosteronism (alone
or
with other diuretics for added diuretic or antikaliuretic effects)
Contraindications/cautions
Contraindicated in the presence of allergy to triamterene,
hyperkalemia,
renal disease (except nephrosis), liver disease, lactation.
Use caution in the presence of diabetes mellitus, pregnancy.
Adverse effects
- CNS: Headache, drowsiness, fatigue, weakness
- GI: Nausea, anorexia, vomiting, dry mouth, diarrhea
- Hematologic: Hyperkalemia, blood dyscrasias
- GU: Renal stones, intersititial nephritis
- Dermatologic: Rash, photosensitivity
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