by R. Zein, Pharm D on Tue Sep 20, 2005 3:02 pm
During each heartbeat, the heart contracts and relaxes. When your heart contracts (systole), it ejects blood from the pumping chambers (ventricles). When your heart relaxes (diastole), the ventricles refill with blood. No matter how forceful the contraction, it doesn't empty all of the blood out of a ventricle. The term ejection fraction refers to the percentage of blood that is pumped out of a filled ventricle with each heartbeat. This measures the capacity at which your heart is pumping.
Because the left ventricle is the heart's main pumping chamber, ejection fraction is usually measured in the left ventricle. A normal ejection fraction is 55 percent to 70 percent. The ejection fraction may decrease when the heart muscle has been damaged, such as due to: Heart attack , or Heart muscle disease (cardiomyopathy), and
Heart valve problems
so ejection fraction of less than 50 indicates a form of heart failure, of course once it is the 20 range or less, this might indicate severe CHF
THANK YOU
Riham Zein, Pharm.D., Ph.D.
Clinical Pharmacy Specialist