Powered by


                    Home  |  Forums  |  Humor  |  Advertising  |  Contact
   Health Questions

   News via RSS






   Forum Archives





















   Primary Care






   Other Sections


   Research Tools

   Medical Tutorials

   Medical Software






Back to Cardiovascular Labs

Creatine kinase

This is one of the most sensitive indicators of myocardial injury. Creatine kinase is found primarily in the heart, skeletal muscle, and brain. Acute liver damage has no effect on CK. CK may be elevated in acute muscular damage (such as seen with hypodermic injections), hepatic coma, and delirium tremens.

The specimen should be drawn before injection or at least one hour after injection. Trauma to muscle during surgery makes CK unreliable for a few postoperative days.


Isoenzyme determinations of CK are also becoming widely available today. There are three major categories: CK-BB (as found in brain and lung), CK-MM (as found in skeletal muscle), and the hybrid CK-MB (in cardiac muscle).

The CK-MB level begins to rise 3-6 hours after onset of infarct, peaks in 12-24 hours, and returns to normal in 24-48 hours. There is a rough correlation between the size of the infarct and the degree of CK-MB isoenzyme elevation.

advertisement.gif (61x7 -- 0 bytes)

Are you a doctor or a nurse?

Do you want to join the Doctors Lounge online medical community?

Participate in editorial activities (publish, peer review, edit) and give a helping hand to the largest online community of patients.

Click on the link below to see the requirements:

Doctors Lounge Membership Application

previous.gif (72x17 -- 347 bytes) next.gif (72x17 -- 277 bytes)

 advertisement.gif (61x7 -- 0 bytes)