Back to Chest Drug index

Back to Antihistamines

Name: Astemizole

	Asthma News
	Xolair reduced the rate of hospital emergency visits by 44% in patients with inadequately controlled asthma.
	send to a friend   printer friendly version
	related discussion
	Related   Asthma

Pregnancy Category C

Drug classes of Astemizole

Antihistamines (nonsedating type)

Mechanism of action of Astemizole

Competitively blocks the effects of histamine at peripheral H1 receptor sites; has anticholinergic (atropine-like) and antipruritic effects.

Indications of Astemizole

1. Relief of symptoms associated with perennial and seasonal allergic rhinitis; vasomotor rhinitis; allergic conjunctivitis; mild, uncomplicated urticaria and angioedema
2. Amelioration of allergic reactions to blood or plasma
3. Dermatographism
4. Adjunctive therapy in anaphylactic reactions

Contraindications of Astemizole

1. Allergy to any antihistamines
2. Narrow-angle glaucoma
3. Stenosing peptic ulcer
4. Symptomatic prostatic hypertrophy
5. Asthmatic attack
6. Bladder neck obstruction
7. Pyloroduodenal obstruction
8. Lactation

Adverse effects of Astemizole

• CNS: Headache, nervousness, dizziness, depression
• GI: Appetite increase, nausea, diarrhea, abdominal pain
• CV: Palpitation, edema
• Respiratory: Bronchospasm, pharyngitis
• General: Weight gain
• Other: Fever, photosensitivity, rash, myalgia, arthralgia, angioedema

		Are you a doctor or a nurse? Do you want to join the Doctors Lounge online medical community? Participate in editorial activities (publish, peer review, edit) and give a helping hand to the largest online community of patients. Click on the link below to see the requirements: Doctors Lounge Membership Application

send to a friend printer friendly version

The Chest Discussion Board     Asthma Forum       Pneumonia Forum       Chest symptoms Forum The Chest  Diseases Articles