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Back to Chest Drug index

Back to Antihistamines

Brand Name: Bonamine
Name: Meclizine

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Pregnancy Category B

Drug classes of Bonamine

Antihistamines (sedating type)

Mechanism of action of Bonamine

Has central anticholinergic action by blocking the chemoreceptor trigger zone. It also decreases excitability of the middle ear labyrinth and blocks conduction in the middle ear vestibular-cerebellar pathways.

Indications of Bonamine

  1. Prevention and treatment of symptoms of motion sickness; management of vertigo and diseases affecting the vestibular system

Contraindications of Bonamine

  1. Allergy to any antihistamines
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Adverse effects of Bonamine

  • CNS: Sedation, sleepiness
  • GI: Appetite increase, nausea, diarrhea, abdominal pain, dry mouth
  • CV: Palpitation, tachycardia, hypotension
  • Respiratory: Thickening of bronchial secretions
  • General: Weight gain
  • Other: Hepatitis, photosensitivity, rash, urticaria, angioedema

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