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Back to Chest Drug index

Back to Antihistamines

Brand Name: Claritin
Name: Loratidine

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Pregnancy Category C

Drug classes of Claritin

Antihistamines (nonsedating type)

Mechanism of action of Claritin

Competitively blocks the effects of histamine at peripheral H1 receptor sites; has anticholinergic (atropine-like) and antipruritic effects.

Indications of Claritin

  1. Relief of symptoms associated with perennial and seasonal allergic rhinitis; vasomotor rhinitis; allergic conjunctivitis; mild, uncomplicated urticaria and angioedema
  2. Amelioration of allergic reactions to blood or plasma
  3. Dermatographism
  4. Adjunctive therapy in anaphylactic reactions

Contraindications of Claritin

  1. Allergy to any antihistamines
  2. Narrow-angle glaucoma
  3. Stenosing peptic ulcer
  4. Symptomatic prostatic hypertrophy
  5. Asthmatic attack
  6. Bladder neck obstruction
  7. Pyloroduodenal obstruction (avoid use or use with caution as condition may be exacerbated by drug effects)
  8. Lactation
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Adverse effects of Claritin

  • CNS: Headache, nervousness, dizziness, depression
  • GI: Appetite increase, nausea, diarrhea, abdominal pain
  • CV: Palpitation, edema
  • Respiratory: Bronchospasm, pharyngitis
  • General: Weight gain
  • Other: Fever, photosensitivity, rash, myalgia, arthralgia, angioedema

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