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Back to Chest Drug index
Brand Name: Genahist
Name: Diphenhydramine
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Xolair reduced the rate of hospital emergency visits by 44% in
patients with inadequately controlled asthma.
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 related discussion |
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Pregnancy Category B
Drug classes of Genahist
Antihistamines (sedating type)
Mechanism of action of Genahist
Competitively blocks the effects of histamine at peripheral H1 receptor
sites; has anticholinergic (atropine-like) and sedative effects.
Indications of Genahist
- Relief of symptoms associated with perennial and seasonal allergic
rhinitis; vasomotor rhinitis; allergic conjunctivitis; mild, uncomplicated
urticaria and angioedema
- Amelioration of allergic reactions to blood or plasma
- Dermatographism
- Adjunctive therapy in anaphylactic reactions
- Mild nighttime sedation
- Prevention of motion sickness
- Antinauseant
- Topical anesthetic
- Treatment of antipsychotic induced extrapyramidal symptoms
Contraindications of Genahist
- Allergy to any antihistamines
- Asthmatic attack
- Not to be used in neonates
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Adverse effects of Genahist
- CNS: Sedation, sleepiness,
headache, nervousness, dizziness, euphoria
- GI: Appetite increase, nausea,
diarrhea, abdominal pain
- CV: Palpitation, tachycardia,
hypotension
- Respiratory: Thickening of
bronchial secretions
- Hematology: Hemolytic anemia,
thrombocytopenia, agranulocytosis
- General: Weight gain
- Other: Photosensitivity,
rash, urticaria, angioedema
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