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Back to Chest Drug index

Back to Antihistamines

Brand Name: Meni-D
Name: Meclizine

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Pregnancy Category B

Drug classes of Meni-D

Antihistamines (sedating type)

Mechanism of action of Meni-D

Has central anticholinergic action by blocking the chemoreceptor trigger zone. It also decreases excitability of the middle ear labyrinth and blocks conduction in the middle ear vestibular-cerebellar pathways.

Indications of Meni-D

  1. Prevention and treatment of symptoms of motion sickness; management of vertigo and diseases affecting the vestibular system

Contraindications of Meni-D

  1. Allergy to any antihistamines
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Adverse effects of Meni-D

  • CNS: Sedation, sleepiness
  • GI: Appetite increase, nausea, diarrhea, abdominal pain, dry mouth
  • CV: Palpitation, tachycardia, hypotension
  • Respiratory: Thickening of bronchial secretions
  • General: Weight gain
  • Other: Hepatitis, photosensitivity, rash, urticaria, angioedema

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