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Back to Chest Drug index
Brand Name: Optivar
Name: Azelastine
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Xolair reduced the rate of hospital emergency visits by 44% in
patients with inadequately controlled asthma.
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 related discussion |
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Pregnancy Category C
Drug classes of Optivar
Antihistamines
Mechanism of action of Optivar
Competitively blocks the effects of histamine at peripheral H1 receptor
sites; has sedative effects.
Indications of Optivar
- Nasal spray: Relief of symptoms associated with seasonal allergic
rhinitis; sneezing, nasal pruritus, vasomotor rhinitis.
- Ophthalmic: allergic conjunctivitis.
Contraindications of Optivar
- Allergy to any antihistamines
- Narrow angle glaucoma
- Bladder neck obstruction
- Symptomatic prostatic hypertrophy
- Asthmatic attack
- Stenosing peptic ulcer
- Pyloroduodenal obstruction
- Not to be used in neonates (possible association with SIDS)
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Adverse effects of Optivar
- CNS: Sedation, sleepiness,
headache, nervousness, dizziness, euphoria
- GI: Appetite increase, nausea,
diarrhea, abdominal pain
- Respiratory: Thickening of
bronchial secretions
- General: Weight gain
- Other: Photosensitivity,
rash, urticaria, angioedema, urine retention
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