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Brand Name: Optivar
Name: Azelastine

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Pregnancy Category C

Drug classes of Optivar

Antihistamines

Mechanism of action of Optivar

Competitively blocks the effects of histamine at peripheral H1 receptor sites; has sedative effects.

Indications of Optivar

  1. Nasal spray: Relief of symptoms associated with seasonal allergic rhinitis; sneezing, nasal pruritus, vasomotor rhinitis.
  2. Ophthalmic: allergic conjunctivitis.

Contraindications of Optivar

  1. Allergy to any antihistamines
  2. Narrow angle glaucoma
  3. Bladder neck obstruction
  4. Symptomatic prostatic hypertrophy
  5. Asthmatic attack
  6. Stenosing peptic ulcer
  7. Pyloroduodenal obstruction
  8. Not to be used in neonates (possible association with SIDS)

Adverse effects of Optivar

  • CNS: Sedation, sleepiness, headache, nervousness, dizziness, euphoria
  • GI: Appetite increase, nausea, diarrhea, abdominal pain
  • Respiratory: Thickening of bronchial secretions
  • General: Weight gain
  • Other: Photosensitivity, rash, urticaria, angioedema, urine retention

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