| |
Back to Chest Drug index
Name: Clemastine
|
|
|
Xolair reduced the rate of hospital emergency visits by 44% in
patients with inadequately controlled asthma.
|
|
|
|
|
| |
 related discussion |
|
|
|
|
|
|
|
|
|
|
|
Pregnancy Category B
cromolyn sodium
disodium cromoglycate, cromoglicic acid, cromoglycic acid
Gastrocrom
Respiratory inhalant, nasal solution, ophthalmic solution: Intal,
Nasalcrom, Opticrom 4%
Pregnancy Category B
Drug classes
Antiasthmatic drug (prophylactic)
Antiallergic drug
Therapeutic actions
Inhibits the allergen-triggered release of histamine and slow-releasing
substance of anaphylaxis, leukotriene, from mast cells; decreases the
overall allergic response.
Indications
Respiratory inhalant: Prophylaxis of severe bronchial asthma; prevention
of exercise-induced bronchospasm
Nasal preparations: Prevention and treatment of allergic rhinitis
Ophthalmic solution: Treatment of allergic disorders (vernal
keratoconjuctivitis and conjunctivitis, giant papillary conjunctivitis,
vernal keratitis, allergic keratoconjunctivitis)
Oral use: orphan drug use-mastocytosis
Unlabeled uses: prevention of GI and systemic reactions in patients with
food allergies; treatment of eczema, dermatitis, ulcerations, urticaria
pigmentosa, chronic urticaria, hay fever, postexercise bronchospasm
Contraindications/cautions
Allergy to cromolyn, pregnancy, lactation.
Respiratory inhalant and nasal products: Impaired renal or hepatic
function.
Adverse effects
Respiratory Inhalant Product
CNS: Dizziness, headache, lacrimation
GI: Nausea, dry and irritated throat, swollen parotid glands
GU: Dysuria, frequency
Dermatologic: Urticaria, rash, angioedema, joint swelling and pain
Nebulizer Solution
GI: Abdominal pain
Respiratory: Cough, nasal congestion, wheezing, sneezing, nasal itching,
epistaxis, nose burning
Nasal Solution
CNS: Headaches
GI: Bad taste in mouth
Respiratory: Sneezing, nasal stinging or burning, nasal irritation,
epistaxis, postnasal drip
Dermatologic: Rash
Ophthalmic Solution
Local: Transient ocular stinging or burning on instillation
Oral
CNS: Dizziness, fatigue, paresthesia, headache, migraine, psychosis,
anxiety, depression, insomnia, behavior change, hallucinations, lethargy
GI: Taste perversion, diarrhea, esophagospasm, flatulence, dysphagia,
hepatic function tests abnormality, burning in the mouth and throat
Dermatologic: Flushing, urticaria, angioedema, skin erythema and burning
Drug classes of Clemastine
Antihistamines (sedating type)
Mechanism of action of Clemastine
Competitively blocks the effects of histamine at peripheral H1
receptor sites.
Indications of Clemastine
- Relief of symptoms associated with perennial and seasonal allergic
rhinitis; vasomotor rhinitis; allergic conjunctivitis; mild, uncomplicated
urticaria and angioedema
- Amelioration of allergic reactions to blood or plasma
- Dermatographism
- Adjunctive therapy in anaphylactic reactions
Contraindications of Clemastine
- Allergy to any antihistamines
- Narrow angle glaucoma
|
|
|
|
Are you a doctor or a nurse?
Do you want to join the Doctors Lounge online medical community?
Participate in editorial activities (publish, peer review, edit) and
give a helping hand to the largest online community of patients.
Click on the link below to see the requirements:
Doctors Lounge Membership
Application |
|
Adverse effects of Clemastine
- CNS: Sedation, sleepiness,
dyscoordination, somnolence, headache, dizziness, nervousness
- GI: Epigastric distress
- CV: Palpitation, tachycardia,
hypotension
- Respiratory: Thickening of
bronchial secretions
- General: Weight gain
- Other: Photosensitivity,
rash, urticaria, angioedema
|
|
send
to a friend
printer
friendly version
