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Forum Name: Miscellaneous Chest Diseases

Question: pulminary fibrosis


 happy1234 - Tue Aug 10, 2010 4:08 pm

my husband's mother died of IPF. Should we be worried that he will get this disease?
 Dr.M.jagesh kamath - Mon Sep 06, 2010 2:53 am

User avatar Hello,There are a few cluster of families with Idiopathic pulmonary fibrosis .A pair of identical twins with IPT has been reported .Some of the FIPF family members had high peripheral blood eosinophilia,and serum globulin anomalies.Familial idiopathic pulmonary fibrosis( FIPF) is defined when two are more of a family are affected. Sporadic cases make up for most of IPF cases.The familial cases had an earlier age of onset.
"While single gene defects have yet to be identified, a recent and
intriguing report described polymorphisms of hTERT and
hTR in a cohort of patients with familial IPF"
Orphanet Journal of Rare Diseases 2008, 3:8 doi:10.1186/1750-1172-3-8.Review-
"Idiopathic pulmonary fibrosis"
Eric B Meltzer* and Paul W Noble
Cigarette smoking has been consistently identified with IPF.
So assuming that your husband's mother had a sporadic form it is unlikely that your husband would develop the condition.
Do consult your physician in any case.Best wishes.

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