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Forum Name: Dermatology Topics

Question: Granulation Tissue and Scars


 roperneal - Sun May 31, 2009 10:17 pm

Lately i have been reading a lot about wound healing and the formation of scar tissue because of sheer interest. I am, however, confused about the permanence of granulation tissue in the proliferative phase. Is this tissue the actual scar tissue that persists after the wound healing is complete? If so, is it possible for granulation tissue to absorbed by the body (removed) by a treatment like theraputic massage?

Thank you very much,
Neal
 Dr.M.jagesh kamath - Tue Aug 25, 2009 3:03 am

User avatar Hello,Granulation tissue is the precursor tissue in wound healing containing vascular endothelium which helps in epithelialization.The collagen laying ultimately decides the scar tissue.The provisional extracellular matrix produced by the granulation tissue is resorbed by the keratinization.If collagen laying is disturbed scar tissue forms.The whole wound healing is an orchestrated phenomenon involving many growth factors.In secondary intention a broader scar forms but may no per se related to the granulation tissue but the size of the wound,and accompanying secondary infection.As to whether massage may help is highly speculative.

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