Powered by


                    Home  |  Forums  |  Humor  |  Advertising  |  Contact
   Ask a Doctor

   News via RSS







   Forum Archives





















   Primary Care






   Other Sections


   Research Tools

   Medical Tutorials

   Medical Software




Back to Endocrinology Drug Index

Back to Sulfonylureas

Name: Glipizide

Pregnancy Category C

Drug classes

  • Antidiabetic agent
  • Sulfonylurea, second generation

Therapeutic actions

Stimulates insulin release from functioning beta cells in the pancreas; may improve binding between insulin and insulin receptors or increase the number of insulin receptors; more potent in effect than first-generation sulfonylureas.


Adjunct to diet to lower blood glucose in patients with non-insulin-dependent diabetes mellitus (Type II) Adjunct to insulin therapy in the stabilization of certain cases of insulin-dependent maturity-onset diabetes, reducing the insulin requirement and decreasing the chance of hypoglycemic reactions


Allergy to sulfonylureas; diabetes complicated by fever, severe infections, severe trauma, major surgery, ketosis, acidosis, coma (insulin is indicated in these conditions); Type I or juvenile diabetes, serious hepatic impairment, serious renal impairment, uremia, thyroid or endocrine impairment, glycosuria, hyperglycemia associated with primary renal disease; labor and delivery (if glipizide is used during pregnancy, discontinue drug at least 1 mo before delivery); lactation.

Adverse effects

  • GI: Anorexia, nausea, vomiting, epigastric discomfort, heartburn, diarrhea
  • CV: Increased risk of cardiovascular mortality
  • Hematologic: Leukopenia, thrombocytopenia, anemia
  • Hypersensitivity: Allergic skin reactions, eczema, pruritus, erythema, urticaria, photosensitivity, fever, eosinophilia, jaundice
  • Endocrine: Hypoglycemia
advertisement.gif (61x7 -- 0 bytes)

Are you a doctor or a nurse?

Do you want to join the Doctors Lounge online medical community?

Participate in editorial activities (publish, peer review, edit) and give a helping hand to the largest online community of patients.

Click on the link below to see the requirements:

Doctors Lounge Membership Application


 advertisement.gif (61x7 -- 0 bytes)



We subscribe to the HONcode principles of the HON Foundation. Click to verify.
We subscribe to the HONcode principles. Verify here

Privacy Statement | Terms & Conditions | Editorial Board | About us
Copyright 2001-2012 DoctorsLounge. All rights reserved.