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Doctors Lounge - Endocrinology Answers
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| skimom
- Wed May 30, 2007 10:13 pm |
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Can spironolactone increase potassium levels in someone who has normal adrenal glands In other words, if spironolactone corrects a low potassium problem, is that a guarantee that an adrenal problem is present?
If aldosterone and renin levels are tested (blood and urine) when a person is taking spironolactone, would the results be accurate?
This is a great web site! Thanks in advance!
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| Dr. Chan Lowe
- Fri Jul 06, 2007 2:25 am |
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 Spironolactone can increase potassium levels in normal individuals as well. This occurrence does not mean there is a problem with the adrenal glands.
The renin and aldosterone levels may or may not be affected by the spironolactone. I would tend to think that the aldosterone levels, in particular, would be affected because spironolactone can cause electrolyte variations that aldosterone responds to. Unfortunately I am not knowledgeable enough about this to answer this part of your question definitively.
Best wishes.
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