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Forum Name: Endocrinology Topics

Question: Possible Cushings - Low Testosterone?


 adam00 - Thu May 28, 2009 2:00 pm

I'm a 19 year old male, that feels like a 13 year-old boy sometimes... Blood work and Urine Tests are below...

What I'm experiencing is:
*Central Obesity
*Moon Face
*Buffalo Hump
*Excessive Body Hair Inconsistent With Familial History
*Extreme Fatigue
*Relatively High Pitched Voice in comparison to peers
*Non-Broadening of Shoulders
*Feel younger than peers that even I am older than
*Small Penis/Underdeveloped
*Hypertension
*Heart Palpitations
*High Blood Pressure
*Red Face
*Acne
*Anxiety/Depression
*Trouble Getting To Sleep Even Though Tired


What concerns me the most is while they consider my testosterone 'normal', it's 368, and in combination with my symptoms and age, couldn't this be considered low? Additionally, as you can see from the below lab work, I've out-of-range (high) cortisol levels, and out of range (extremely low) ACTH levels.

*Being that normally High Cortisol + Low ACTH = Cushing's Syndrome w/ Adrenal Tumor, could Adrenal caused Cushing's Syndrome cause Low Testosterone Levels?

*My doctor ordered two additional UFC's to compare to what are below, and we're waiting to hear back.... but in interim.... what is your input based on what we know right now?

*Testosteorne. 368.... Is this Low? I think my penis is smaller than normal... my voice is not very deep.... my bone structure hasn't really changed imho... I feel younger than my peers.... Even though 368 is within 'range'... could it be low? 350-1500 is a big range...


Test

Aldosterone
Result: 4.3 ng/dl Reference Range: 3.0-10.0

Plasma Renin Activity
Result: 1.8 ng/ml/h Reference Range: 0.6-4.3

Cortisol AM
Result: 1.3 mcg/dL Reference Range: <1.8 (Low Dose DST Suppression)
Adrenocorticotropin Hormone (ACTH)
Result: < 5 pg/mL Reference Range: 7.0-50.0
Total Testosterone
Result: 368 ng/dl Range: 262-1593
Free Testosterone
Result: 12.3 ng/dl Range: 7.4-22.6
Luteinizing Hormone (LH)
Result: 2.9 U/L Range: 1.0-9.0
Follicle-Stimulating Hormone (FSH)
Result: 2.4 U/L Range: 5.0-15.0
17 OH Progesterone
Result: 130 ng/dl Range <200
Cortisol,Free,Urine
Result: 33.8 mcg/gcreat Range: 1.3-27.5
Creatinine,24 Hour Urine
Result: 2.27 g/24h Range: 0.63-2.50
Cortisol,Free,24 Hour Urine
Result: 76.8 mcg/24h Range: 4.0-50.0
 adam00 - Mon Jun 01, 2009 5:50 pm

here's some updated labs... someone please help...

Test Name Result Unit Range
Cortisol,Free,Urine 33.8 mcg/gcreat 1.3-27.5
Creatinine,24 Hour Urine 2.27 g/24h 0.63-2.50
Cortisol,Free,24 Hour Urine 76.8 mcg/24h 4.0-50.0
Cortisol,Free,Urine Results Not Available
Creatinine,24 Hour Urine As Of Last Update
Cortisol,Free,24 Hour Urine 90 mcg/24h 4.0-50.0
Cortisol,Free,Urine
Creatinine,24 Hour Urine 2.63 g/24h 0.63-2.50
Cortisol,Free,24 Hour Urine 83.8 mcg/24h 4.0-50.0

Test Name Result Unit Range
Salivary Cortisol 0.06 mcg/dL < OR = 0.09
Salivary Cortisol 0.05 mcg/dL < OR = 0.09
Salivary Cortisol 0.04 mcg/dL < OR = 0.09

Aldosterone 4.3 ng/dl 3.0-10.0
Plasma Renin Activity 1.8 ng/ml/h 0.6-4.3
Cortisol AM 1.3 mcg/dL <1.8
Adrenocorticotropin Hormone (ACTH) < 5 pg/mL 7.0-50.0
Total Testosterone 368 ng/dl 262-1593
Free Testosterone 12.3 ng/dl 7.4-22.6
Luteinizing Hormone (LH) 2.9 U/L 1.0-9.0
Follicle-Stimulating Hormone (FSH) 2.4 U/L 5.0-15.0
17 OH Progesterone 130 ng/dl <200
Sodium 140 mmol/L 135-146
Glucose 93 mg/dl 65-99

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