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Forum Name: Endocrinology Topics

Question: Thyroxine Implant? Is there such a thing?


 shazalic - Thu Oct 15, 2009 11:48 pm

Today I was declined entry into Australian Army Reserve due to Hypothyroidism. My thyroid was removed 1997. I am now 33 years old. I am currently on 200mg Thyroxine daily. Is there a slow release Thyroxine Implant available as an alternative to the daily tablet I am currently taking? (like the Implanon)??
 Dr.M.Aroon kamath - Tue Nov 03, 2009 12:35 am

User avatar Hi,
Implantable drug delivery systems (IDDS) are evolving & being developed.

As you rightly pointed out, ' Implanon' is available.It is a
single-rod, sub-dermal, long acting & reversible hormonal contraceptive implant.

At present, the limitation of these drug delivery systems is the fact that their cost-to-benefit ratio is too high which restricts their use over conventional dosage forms of currently available drugs.
Situation is likely to change in the future.

Induction of experimental thyroid dysfunction in rats with implantable pellets of thyroxine or propylthiouracil has been tried.

To the best of my knowledge, Implantable drug delivery systems for thyroxin are currently unavailable.
Good luck!

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