Hello,
One of the serious effects of narcotic like hydrocodones is increase in the intracranial CSF pressure, resulting in undesired neurologic symptoms and respiratory depressant effects.
These effects are more likely and more severe if there is a recent head injury or any intracranial lesion or any cause that may increase the intracranial pressure. So physicians must check well the history of their patients before they prescribe it.
Regarding its effect as a carciogenic, there is no data that supports or reject this issue so simply there are no data. Interestingly, these compounds are commonly used in
pain management in cancer patients.
I assume your physician asked you about a history of head injury or brain tumor mainly to be sure there will be no serious effects on the neurologic system or on the respiratory functions. You can always discuss with your doctor these concerns.
Hope you find this useful.
Best regards.
This answer does not substitute for direct medical consultation.
Dr. Safaa Mahmoud.
MB BCh, MSc Internal Medicine. MD Medical Oncology.
PhD Experimental Medicine and Biochemical Science.