If your wife had a sore throat, and now she has a little nodule in the neck, and hurts when you touch it, the most probably thing is that you found a reactive lymph node;these are seen frequently with or after head or neck infections.
Sometimes, depending on several factors (like type and severity of infection), the reactive lymph nodes can be found in the neck even weeks after the cause is gone.
You may be concern if the bump starts growing fast. I don't think you have to worry about it.
Hope Katrina goes far away from you.