I apologize for the delayed response but I thought I would answer all the same. I hope your mother is doing well. What kind of pelvic tumor are we talking about - was it an endomtrial (uterine) carcinoma? a squamous cell cancer of the cervix? Please elaborate.
I believe, the estradiol she was prescribed would not be related to her diagnosis of cancer? You are right that there are convincing reports about the increased risk of breast cancer and ovarian cancer with the use of estradiol. In the case of endometrial (uterine) cancer this risk refers to patients with an intact uterus not those who have had it removed.
I hope that helps.
Dr. Tamer Fouad, MD
MB, BCh, MSc Internal Medicine.
Consultant of Hematology - Oncology.