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N-acetylcysteine with Acetaminophen?

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N-acetylcysteine with Acetaminophen?

Postby MuzicLov3r » Tue Mar 11, 2008 1:01 pm

If I took the reccommended dosage of N-acetylcysteine with an higher than normal dose of Acetaminophen (Tylenol), would the N-acetylcysteine help cushion the liver and prevent hepatotoxicity?
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Re: N-acetylcysteine with Acetaminophen?

Postby Dr. Chan Lowe » Tue Mar 11, 2008 7:57 pm

Hello MuzicLov3r,

N-acetylcysteine (NAC) is a compound that is used when too much tylenol has been ingested to help prevent liver damage. Basically, it helps prevent the tylenol from being metabolized via a secondary pathway that creates a metabolite toxic to the liver.

In theory, taking NAC at the same time as the tylenol could potentially help prevent damage from too much tylenol; however, this cannot be guaranteed. In addition, I would strongly recommend against a patient using NAC to be able to take a larger dose of tylenol than is approved/appropriate. The side effects and the actual outcomes can potentially be different than expected and liver damage cannot be absolutely predictably prevented.

Best wishes.
Advice and opinions given are based on the information provided and must not be used as an official medical recommendation. The limitations of the internet prevent an appropriate evaluation. Always consult your doctor if there is concern.
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