Plasma monitoring to adjust dosages in a prescribed antidepressant are used when a patient is already on an antidepressant. Since depression is from the imbalance in brain chemistry and decreased serotonin levels, there are possible genetic testing to see what you would need.
A psychiatrist could identify this genetic variant and then steer you to a different class of antidepressants. Other genes may play a role in the adverse effects. This new field may also help find what drugs may produce toxic side effects to the patient. It can be tricky, since nearly all drugs are metabolized by a group of enzymes that vary greatly in activity from person to person. If you have a genetic mutation that results in either deficient enzyme activity or none, they would be likely to have serious side effects if you were exposed to the drug that is metabolized by the enzyme.
A patient can be routinely screened for these genetic variations wich will tell your doctor which drugs to avoid. this could prevent major drug toxicity , which is a major cause of illness and death. I wish you lots of luck on your results to find a psychiatrist who will do this testing. There seems to be some states that have a higher percentage rate that do the testing.
With new technology, it is a positive thing besides trial and error for use of antidepressants. So many people have to be on a numerous amount before finding the right one.
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