Celexa and Wellbutrin are two different types of
antidepressants, and both have possible side effects of everything from fatigue to
mania, depending on how a person metabolizes them.
I would assume that you are already on the
antidepressant combination, so you already know what, if any, your reactions have been. Your physician must know if you add cannibis (or want to add cannibis) to your regimen so that he/she will not misdiagnose a change in mood or other reaction you may have.
Adding cannibis can magnify any reactions. Cannibis can increase the risk of
seizures, can bring on
panic attacks, paranoia, can be a risk factor for
schizophrenia, and can exacerbate depressive symptoms. At the same time it could possibly bring on feelings of elation, or "high". Be aware also that cannibis can cause irregular heart rhythm.
There are no direct studies available to me concerning the combination of these 3 specific medications. Even if there were studies, there is still no guarantee that any specific person would have those reactions. Keep in mind that the
antidepressants can possibly cause weight gain...and cannibis is medically used to initiate weight gain.
In summary, there are no documented contraindications for the combinations of these 3 medications outside that each may exacerbate the reactions of the others or can exacerbate the reasons you are taking the
antidepressants.
Again, be sure to discuss the possible reactions of each medication alone and in combinations with your physician. Your medical history needs to be checked thoroughly for any significant risk factors.
