Cirrhosis (irreversible inflammation of the liver) can present with the symptoms you have described however we would need to know more information from her history and physical and testing to know this for sure.
Vitamin D deficiency leads to bone loss.
Causes of Vitamin D deficiency includes:
poor absorbtion in the gut
mal nourishment (decrease intake of calcium)
lack of sun exposure
kidney or liver disease
stomach surgery (including gastric bypass)
Medications (eg some anti convulsants, long term corticosteroid use)
It may be helpful if your friend is willing to have a health advocate (someone who will go with her to doctor's visits, tests, or procedures - to give support and help in relationship with physicians).
All the best to your friend.
Keep us posted.
Tom Plamondon PA-C, PT