albumin/globulin ratio

Non-malignant hematology topics. For Leukemias and lymphomas please use the Oncology (Cancer) Forums.

Moderators: Radiodiagnosis Team, Primary Care Team, Cardiology Team

Forum rules
YOUR POST WILL REQUIRE APPROVAL - READ: Doctors Lounge Forum Rules and Regulations
• Use a precise title for your question otherwise it will NOT be approved.
• Do not post the same question more than once & maintain related posts in original thread.
• Do not use your real name or identifiable information - You can't edit/delete your post.
Posts: 2
Joined: Sat Dec 10, 2005 3:43 pm
Location: texas

albumin/globulin ratio

Postby yahoo » Sat Dec 10, 2005 4:01 pm

My globulin level is 4.2 and my albumin/globulin ratio is 0.8, which is considered to be low. I bruise easily. I also have ulcerative colitis and enteropathic arthritis. I take about 3 to 4 tramadol a day for pain management. Why is my A/G ration low?

User avatar
Dr. Safaa Mahmoud
Medical Doctor
Posts: 1434
Joined: Sat Jan 04, 2003 7:53 am

Postby Dr. Safaa Mahmoud » Sun Jul 16, 2006 7:53 pm

Dear yahoo,

The normal serum ablumin range is 3.4 to 5.4 g/dL.

Absolute increase in serum albumin content is only seen after infusion of hyperoncotic albumin suspensions.

Relative increase is seen in cases of in hemoconcentration.

Decreased serum albumin is due to many causes which include:
-Decreased synthesis in malnutrition, malabsorption, liver disease, and other chronic diseases.
- Increased loss in nephrotic syndrome, many GI conditions, thermal burns, etc.
- Increased catabolism in thyrotoxicosis, cancer chemotherapy, Cushing's disease, familial hypoproteinemia.

Globulin is increased disproportionately to albumin resulting in decreasing the albumin/globulin ratio in disorders due to :
- Chronic inflammation Like inflammatory bowel diseases e.g. Ulcerative colitis.
- B-lymphocyte neoplasms such as myeloma and Waldenstrom's macroglobulinemia.

Decreased globulin may be seen in congenital or acquired hypogammaglobulinemic states.

I hope these informations are helpful.

I advise you to follow up with your doctor and to update him with any new symptoms.

Best regards,
This answer does not substitute for direct medical consultation.

Dr. Safaa Mahmoud.
MB BCh, MSc Internal Medicine. MD Medical Oncology.
PhD Experimental Medicine and Biochemical Science.

Return to “Hematology Topics”

Who is online

Users browsing this forum: No registered users and 2 guests

advertisement.gif (61x7 -- 0 bytes)

We subscribe to the HONcode principles of the HON Foundation. Click to verify.
We subscribe to the HONcode principles. Verify here

Privacy Statement | Terms & Conditions | Editorial Board | About us
Copyright © 2001-2016 Doctors Lounge. All rights reserved.