The normal serum ablumin range is 3.4 to 5.4 g/dL.
Absolute increase in serum albumin content is only seen after infusion of hyperoncotic albumin suspensions.
Relative increase is seen in cases of in hemoconcentration.
Decreased serum albumin is due to many causes which include:
-Decreased synthesis in malnutrition, malabsorption, liver disease, and other chronic diseases.
- Increased loss in nephrotic syndrome, many GI conditions, thermal burns, etc.
- Increased catabolism in thyrotoxicosis, cancer chemotherapy, Cushing's disease, familial hypoproteinemia.
GLOBULIN, A/G RATIO
Globulin is increased disproportionately to albumin resulting in decreasing the albumin/globulin ratio in disorders due to :
- Chronic inflammation Like inflammatory bowel diseases e.g. Ulcerative colitis.
- B-lymphocyte neoplasms such as myeloma and Waldenstrom's macroglobulinemia.
Decreased globulin may be seen in congenital or acquired hypogammaglobulinemic states.
I hope these informations are helpful.
I advise you to follow up with your doctor and to update him with any new symptoms.
This answer does not substitute for direct medical consultation.
Dr. Safaa Mahmoud.
MB BCh, MSc Internal Medicine. MD Medical Oncology.
PhD Experimental Medicine and Biochemical Science.