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factor II gene >99%...what does this mean???

Non-malignant hematology topics. For Leukemias and lymphomas please use the Oncology (Cancer) Forums.

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factor II gene >99%...what does this mean???

Postby luvumason » Thu May 22, 2008 12:03 pm

Hi, I recently posted a question about some blood work that I had done and I forgot to add that on one of my labs it says
Methodology:
DNA analysis of the factor II gene was performed by PCR amplification followed by restriction analysis. The diagnostic sensitivity is >99% for both. What does this mean???? On the page before it says
Factor II DNA analysis G20210A
Factor II DNA analysis
Negative
no mutation identified
So, seeing the 99% on the other page had me a little confused.
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Re: factor II gene >99%... does this mean???

Postby John Kenyon, CNA » Tue Jul 29, 2008 11:03 pm

Hello -

What that "99% sensitivity" means is that the test is 99% accurate and has nothinig to do with the findings themselves. That is to say, it is not part of the finding, but merely a measure of the accuracy of the test. At 99% it is virtually absolute.

I hope this clarifies this for you.
John Kenyon, EMT, CCT
Non-invasive cardiology tech, Emergency and Critical Care technician, Critical Incident Stress Mgmt. specialist
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