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Forum Name: Gastroenterology Topics

Question: lymphmic colitis and crohn's


 momofdlj654 - Sat Jan 28, 2006 11:51 pm

I AM A 27 YEAR OLD FEMALE THAT WAS JUST DIAGNOSED WITH LYMPHOMIC COLITIS IN MY UPPER BOWEL AND CROHN'S DISEASE IN MY LOWER BOWEL. HOW RARE IS IT TO HAVE BOTH? WHAT EXACTLY IS LYMPHOMIC COLITIS? I AM ON ENTOCORT FOR THESE PROBLEMS. IS THIS A SAFE MEDICATION? MY MOTHER AND GRANDMA ALSO HAVE CROHN'S.
 Dr. Safaa Mahmoud - Fri Jul 28, 2006 6:34 pm

User avatar Dear momofdlj654,

Crohn's disease is caused by inflammation of the wall of the GI tract. Crohn's disease can occur anywhere in the digestive tract.

Symptoms range from mild to very severe, and can arise suddenly or gradually over a long time and include:
1-Diarrhea which can be watery or bloody.
2-Abdominal pain and camping
3-Loss of appetite and weight are very common sequences of the disease.

In addition other associated symptoms that occur outside the GI include fatiguability, arthritis, eye and sin inflammatory conditions, and hepatitis.

Pathological examination of biopsies taken from the intestine shows lymphoid aggregates that infiltrate the intestinal wall.
These abnormal lymphoid aggregates can occur not only in the active mucosal lesions but also in the unaffected colorectal parts in patients with Crohn's disease.

Colorectal lymphoid aggregates can be seen also in cancer, diverticular as well as inflammatory bowel diseases. The distribution and the size of the aggregates show different pattern with each disease.
In Crohn's disease the aggregates are predominantly basal or trans-mural.

The lymphoid infiltration of the colon (lymphoid colitis) is thought to be part of the pathogenesis of the Crohn's disease, thus it can be detected in non actively affected parts.

Therapies used in the treatment of this diseases can result in long term remission of the symptoms, but not in cure.

Hope you find this information useful,
Best regards,

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