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Forum Name: Hematology Topics

Question: low wbc and high monocyte

nananurse - Wed Dec 20, 2006 10:14 pm

51 year old female with family history of melanoma, bladder cancer and Colon cancer. I just had my yearly physical and was told my wbc was 3. 2 monocytes 10 globulin 2. 2 and alb/glob is 2. 1. Other than feeling a little tired, which is probably normal for everything I do in a day. I have no complaints. I take all the mannatech vitamins and no other medications. I have a skin condition called hailey hailey, but have no breakouts at this time. Could you tell me why my labs are out of wack. They have been taken 3 times with the same result. Thanks, nananurse

Dr. Safaa Mahmoud - Wed Dec 20, 2006 11:09 pm

Hello, Normal values for Globulin : 2. 0–3. 5 g/dL Albumin/globulin ratio: Greater than 1. 0 So, your results are within the normal range. Normal monocyte count ranges from about 4-10% of white blood cells (WBCs). WBCs normal count:4000-11000. Leucopenia is a WBCs count less than 4000. So, your results shows a mild leucopenia. Causes include: -Viral infections -Collagen-vascular diseases -Drugs: like MTX which is used in the treatment of your disease. Have you been on any treatment for the Hailey Hailey disease recently before the blood tests. -Bone marrow, liver, spleen diseases. Follow up with your Doctor is essential. Keep us updated. Best regards.

nananurse - Thu Dec 21, 2006 12:42 pm

I have been on k-flex and minicin for hailey hailey break outs. No other problems.

nananurse - Thu Dec 21, 2006 12:45 pm

The family history of melanoma and other cancer was from my sister and mother. I haven't had any cancers or anything else.

nananurse - Thu Dec 21, 2006 5:21 pm

nananurse wrote: I have been on k-flex and minocin for hailey hailey break outs. No other problems.

Dr. Safaa Mahmoud - Thu Dec 21, 2006 8:25 pm

Hello, I can not find a definitive cause for this mild neutropenia but according to the history you have mentioned possible causes are: - Neutropenia is a reported side effect for keflex(in combination form with Paracetamol), so it may be contributing to the neutropenia especially it is a mild form. - Some people during periods of stress have their leukocyte count lowered for a transient period. - Another possibility to be excluded. Cyclic neutropenia: it is considered if on serial differential blood counts a typical cyclical pattern of blood neutrophils count is seen. (at least 3 times per week over six weeks) to search for the disease. Keep us updated. Best regards.

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