News  |  Journals  |  Conferences  |  Blogs  |  Articles  |  Forums  |  Twitter   



Doctors Lounge - Hematology Answers

"The information provided on is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her physician."

Back to Hematology Answers List

Forum Name: Hematology Topics

Question: Acute chest syndrome

 Jpoy - Sun Nov 25, 2007 2:50 am

34 y/o African American male with history of sickle cell disease, presents with worsening respiratory status. Hypoxic with wheezes on auscultation. CXR shows possible infiltrate left lower lobe. Hemoglobin has dropped from 12.8 to 9.3 over 4 days. No sickling cells noted on blood smear. Blood cultures positive for streptococcus pneumoniae. Receiving antibiotics (Rocephin and Vancomycin for 4 days). Have had to start supportive respiratory oxygenation. Thinking he may be suffering from acute chest syndrome, but he denies chest pain. What do you think?
 Dr. Chan Lowe - Sun Nov 25, 2007 8:52 pm

User avatar Hi Jpoy,

Acute chest syndrome should always be considered in cases like this. The treatment, hydration and possibly blood transfusion, will likely be of use in pneumonia as well-at least the hydration part.

Strep. pneumo is a known severe pathogen for sickle cell patients because the sickling causes destruction of the spleen that helps remove organisms such as strep. pneumo.

Aggressive antibiotics are required. Supportive measures such as intubation and mechanical ventilation can be needed in severe pneumonias.

Best wishes.


Check a doctor's response to similar questions


advertisement.gif (61x7 -- 0 bytes)

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application


 advertisement.gif (61x7 -- 0 bytes)



Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us

Copyright © 2001-2016
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Links | Humor
Forum Archive
CME Articles

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.