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Forum Name: Hematology Topics

Question: giant platelets/low platelets bone marrow biopsy


 cootie1998 - Wed Sep 16, 2009 8:13 pm

My husband has had giant platelets for 2 years and was followed by a hematologist and had some testing for them and we were told to just watch them. Recently he had been feeling more tired than usual and we got sent back to the hematologist because now his platelets are still Giant but also low @ 111. He had a bone marrow biopsy earlier this week and we are going for platelet aggregation this friday. I realize we are most likely looking at a clotting disorder potentially but is leukemia or lymphoma a possibility also? As far as medical hx he has been treated for HTN for 2 years, he quite chewing snuff 2 years ago. Just want some ideas on how serious of an issue we are looking at? He returns to the doctor next week and we are really worried. Thanks for your time.
 Dr.M.jagesh kamath - Mon Nov 16, 2009 2:56 am

User avatar Hello,With giant platelets and low platelet count with out bleeding or clotting disorder one has to think of May-Hegglin anomaly in which giant platelets and inclusion bodies called dohle bodies are found in leucocytes.This is rare but not a serious condition and may not need treatment.Do get a consultation with your hematologist and you can discuss such a possiblity.Best wishes.

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