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Forum Name: Hematology Topics

Question: Low HbA1 and high Hb F


 TonyConcerned - Thu Oct 15, 2009 8:40 am

What does it mean to have 0% hemoglobin A1, 4% hemoglobin A2, 0% hemoglobin C and 96% hemoglobin F
 Dr.M.jagesh kamath - Wed Dec 02, 2009 2:55 am

User avatar Hello,In an adult persisting foetal haemoglobin is seen in certain communities like greeks and black.This is supposed to be due to a genetic mutation.This condition known as Hereditary persistence of foetal haemoglobin HPFH is asymptomatic and would not cause any problems.In foetal life up to 6months 75% and in adults up to 2% of foetal Hb is seen.Thalasemias,anaemias,Hemoglobinopathies,and certain malignancies also show increase in foetal Hb.You may have a false abnormal if you have received transfusions in 12weeks.Do consult a haematologist for further evaluation.Best wishes.

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