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Forum Name: Hematology Topics

Question: COULD TRAUMATIC SPLEENECTOMY CAUSE TYPE 1 DIABETES?


 wendy logan - Wed Sep 14, 2005 6:49 am

MY SON WAS IN A CAR ACCIDENT 2 YEARS AGO. AS A RESULT HIS SPLEEN WAS RUPTURED(REQUIRING SPLEENECTOMY) HE GOT 3 BROKEN RIBS AND SEVERE ABDOMINAL BRUISING. HE WAS GIVEN 2 BAGS OF DONOR BLOOD PROIR TO SURGERY.
HE WAS A FIT AND ACTIVE TEENAGER BEFORE THE ACCIDENT , BUT SINCE THEN HAS BEEN PLAGUED WITH THROAT INFECTIONS AND GENERALLY NOT FEELING 100%.
LAST WEEK HE WAS DIAGONISED WITH TYPE 1 DIABETES. THE ONLY FAMILY HISTORY OF TYPE 1 DIABETES IS HIS GREAT-GREAT GRANDMOTHER AND GREAT- GREAT AUNT.
I WAS WONDERING IF THE PANCREAS COULD HAVE BEEN DAMAGED WHEN THE SPLEEN RUPTURED CAUSING THE ONSET OF DIABETES.
LOOK FORWARD TO HEARING FROM YOU.
WENDY
 Dr. Safaa Mahmoud - Sat Jul 29, 2006 8:18 am

User avatar Dear wendy logan.

Type 1, (juvenile diabetes or insulin-dependent diabetes), is a disorder in which little or no insulin is secreted in the body most commonly due to defect in the body's immune system. The immune system attacks and destroys the cells that produce insulin in the pancreas (Beta cells).When the beta cells are destroyed, no more insulin can be produced, resulting in high level of blood sugar that can negatively affect the other body organs. Genetic factors are believed to play a role in the development of Type 1 diabetes.

The pancreas, is located high in the retroperitoneum (protected), thus being injured in common injuries like car accident is unusual, although it may happen. In such cases splenic or hepatic injuries co- exists.

The diagnosis of small pancreatic injuries is difficult and can be misdiagnosed.
Chronic Pancreatitis (inflammation) , is to be considered in cases with history of traumatic injury to the pancreas. Chronic pancreatiis is one of the conditions that results in type 1 Diabetes. Pancreatic pain (severe agonizing epigastric pain which may radiate to the back accompanied by nausea and vomiting) accompanied by steatorrhoea and loss of weight.

Diagnosis of Chronic Pancreatitis includes:
Pancreas function tests including serum amylase
Ultrasounds
Endoscopic retrograde cholangiopancreatography (ERCP)
CAT scans

For more information about chronic pancreatitis you can visit our website at:
http://www.doctorslounge.com/gastroente ... atitis.htm

For traumatic injury of the pancreas to cause Type 1 diabetes, it should be a severe injury that can not be misdiagnosed clinically and should be associated with other symptoms and signs. However, we can never say never.

Keep on follow up with your doctor, and inform him with any new symptoms. You can discuss with him the above information and the possible investigations to be done for proper management.

Best regards,

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