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Forum Name: Hematology Topics

Question: unusual bone marrow and blood disorder


 jkay - Mon Oct 10, 2005 4:42 pm

I had an operation to remove a bile duct stone it was open surgery. a t -tube clamped was left for 5 months which leaked continuously for that time.I developed anemia and later the HB dropped to 7.2. A bone marrow was done and I was told that I have an unusual blood disorder and the bone marrow formation is one they have never seen before.I was put on Neurecorman and Neupogen.It holds the count but the platlets have gone down then up as well as WBC and HB. This happened after that operation 2 and a half years ago. No family members have ever had any condition like that.
 Dr. Safaa Mahmoud - Sun Jul 16, 2006 9:08 pm

User avatar Dear jkay,
It would be very helpful if you could inform us about:
The CBC results and if a Blood film was done.
The results of the BM study, and whether it was BMA or biopsy.
Any other investigations done and their results,
Your main complaints and any other medical conditions.

I assume that you have pancytopenia, so I will give general informations about this condition.

Decrease number of blood cell elements is called cytopnia. Cytopenia mea be:
-Bicytopenia affecting two of three cell lines
-Pancytopenia: affecting all blood cell lines causing
1.Anemia
2.Leukocytopenia
3.Thrombocytopenia

Causes include:
•Primary Bone Marrow disorder like:Myelofibrosis, MM, and Metastatic Tumors.
•Splenic causes like Lymphoma
•Aplastic Anemia
•Vitamin B12 Deficiency and Folate Deficiency
•Severe infection
•Systemic disease like SLE
•Acquired Aplastic Anemia.
Investigations:
-Complete Blood Count
-Peripheral Film
-Bone Marrow Biopsy:
Normal count or hyperplasia
Dysplasia or Fibrosis like in Myelodysplastic Syndrome.
-Bone Marrow Biopsy: Fat infiltration in Hypoplasia

I hope these informations are helpful.

Best regards,

|

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