Bevacizumab for breast cancer: FDA grants a stay of execution

Author: Dr. A. De la Guerra
Submitted: January 19, 2011. Updated: January 26, 2011.
Category: Gynecology | Oncology | Pharmacy | Research | Surgery

The Food and Drug Administration has after repeated delays proposed removing metastatic breast cancer as an indication from the Avastin label. The proposal is being contested by Roche/Genentech, the drug’s maker. In this article we review the evidence… Read more... (Comments: 0)

New TNM Classification for Lung Cancer. Part II: A review

Author: Dr. A. De la Guerra
Submitted: February 07, 2010. Updated: March 01, 2010.
Category: Oncology | Pulmonology | Radiology | Surgery

The American Joint Committee on Cancer and the Union Internationale Contre le Cancer have redefined the criteria for staging lung cancer based on the proposals made by the International Association for the Study of Lung Cancer, which appeared in the recently… Read more... (Comments: 6)

New TNM Classification for Lung Cancer - Part I: The changes

Author: Dr. A. De la Guerra
Submitted: February 01, 2010. Updated: February 01, 2010.
Category: Oncology | Pulmonology | Radiology | Surgery

Appropriate staging of lung cancer is fundamental for determining the best treatment approach and defining prognosis. After ten years of labor the IASLC has modernized the lung cancer TNM staging system. Revisions to the TNM were determined by differences… Read more... (Comments: 0)

Improved survival in AML with higher anthracycline doses

Author: Tamer M. Fouad, M.D.
Submitted: September 29, 2009. Updated: September 29, 2009.
Category: Hematology | Bone Marrow Transplantation | Oncology | Pharmacy

Younger patients with acute myeloid leukemia (AML) that receive higher doses of anthracyclines during induction chemotherapy are reported to have better complete remission rates in most studies. As of yet, studies have failed to show an improved surivival… Read more... (Comments: 0)

Aspirin Use as Treatment in Colorectal Cancer: Teaching an Old Dog New Tricks

Author: Jeffrey A. Gordon, M.D.
Submitted: September 12, 2009. Updated: September 30, 2009.
Category: Gastroenterology | Oncology | Pharmacy

Aspirin use can decrease the risk of colorectal adenomas.  Full-dose, but not low-dose, aspirin may decrease the risk of developing colorectal cancer.  Whether or not aspirin use can favorably augment survival in patients diagnosed with colorectal… Read more... (Comments: 5)

The Role of Chemotherapy in Advanced Estrogen Receptor Positive Breast Cancer

Author: Tamer M. Fouad, M.D.
Submitted: September 03, 2009. Updated: September 26, 2009.
Category: Gynecology | Oncology

Estrogen receptor positive (ER-positive) breast tumors account for approximately three-quarters of all new cases. Patients with advanced tumors are treated based on the presence of risk factors such as the presence of visceral metastasis, short disease… Read more... (Comments: 3)