Create Account | Sign In: Author or Forum

 
 
News  |  Journals  |  Conferences  |  Blogs  |  Articles  |  Forums  |  Twitter    
 

 Headlines:

 

Category: Family Medicine | Neurology | Nursing | Pediatrics | Pharmacy | Physiotherapy | News

Back to Health News

Injections May Relieve Drooling in Nerve-Damaged Kids

Last Updated: September 22, 2010.

 

Botulinum toxin's effect lasted up to 33 weeks in some, including cerebral palsy patients, study finds

Share |

Comments: (0)

Tell-a-Friend

 

  Related
 
Botulinum toxin's effect lasted up to 33 weeks in some, including cerebral palsy patients, study finds.

WEDNESDAY, Sept. 22 (HealthDay News) -- Botulinum toxin injections may temporarily relieve drooling in children with certain neurological conditions, a new European study has found.

Depending on its severity, drooling can lead to stigmatization and social neglect, numerous daily clothing changes, skin irritation around the mouth, aspiration pneumonia and dehydration, Dr. Arthur Scheffer of Radboud University Medical Center in Nijmegen, the Netherlands, and colleagues noted in a news release about their study.

In the study, Scheffer's team gave botulinum toxin injections to 131 children, average age 10.9 years, with cerebral palsy or other non-progressive neurological conditions, as well as moderate to severe drooling. The injections were confined to the submandibular glands, which are responsible for 70 percent of saliva production while a person is resting.

Two months after the injections, the average drooling quotient had fallen to 15.5 (on a scale of zero to 100) from 28.8 at the start of the study. And, the study authors noted, 61 patients achieved a 50 percent reduction in drooling.

At the eight-month follow-up, the average drooling quotient was 18.7, according to the report in the September issue of the journal Archives of Otolaryngology -- Head & Neck Surgery.

The findings "indicate that most patients who initially respond well to injection can expect an effect to last between 19 and 33 weeks. Although the 46.6 percent success rate might appear low, its safety and efficacy make botulinum toxin a useful first-line invasive treatment if conservative measures have failed," the researchers concluded in the news release from the journal's publisher.

Botulinum toxin injections have been used safely for years, according to the American Academy of Pediatrics. Side effects can include rash, whole-body muscle soreness, difficulty swallowing and weakness in the injected muscles, but they usually go away quickly, the AAP notes.

More information

The March of Dimes has more about cerebral palsy.

SOURCE: JAMA/Archives journals, news release, Sept. 20, 2010

Copyright © 2010 HealthDay. All rights reserved.


Previous: FDA Approves 1st Oral Drug to Reduce MS Relapses Next: Natural Pet Foods May Not Always Be Best Choice

Reader comments on this article are listed below. Review our comments policy.


Submit your opinion:

Name:

Email:

Location:

URL:

Remember my personal information

Notify me of follow-up comments?

advertisement.gif (61x7 -- 0 bytes)
 

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

 
     

 advertisement.gif (61x7 -- 0 bytes)

 

 

Useful Sites
MediLexicon
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2014
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Advertising
Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.