Create Account | Sign In: Author or Forum

News  |  Journals  |  Conferences  |  Opinion  |  Articles  |  Forums  |  Twitter    
Category: Cardiology | Hematology | Neurology | Pharmacy | FDA Approvals

Back to Health News

Xarelto Approved to Prevent Stroke in People With Abnormal Heartbeat

Last Updated: November 04, 2011.


Atrial fibrillation affects more than 2 million Americans

Share |

Comments: (0)




FRIDAY, Nov. 4 (HealthDay News) -- The anti-clotting drug Xarelto (rivaroxaban) has been approved by the U.S. Food and Drug Administration to prevent stroke in people with atrial fibrillation, a common form of irregular heartbeat.

More than 2 million Americans have atrial fibrillation, in which the heart's two upper chambers beat irregularly, the FDA said in a news release. The condition can lead to the formation of a blood clot, which can travel to the brain and cause a stroke. The new drug was approved for cases in which the atrial fibrillation is unrelated to the performance of the heart's valves.

Xarelto's safety and effectiveness were compared to those of another anti-clotting drug, warfarin, in clinical studies involving some 14,000 patients. Xerelto was deemed similar to warfarin in its ability to prevent stroke, the FDA said.

As with other anti-clotting drugs, Xarelto has the ability to cause bleeding, which in rare cases can lead to death, the agency said.

The drug's label has the FDA's most urgent "black box" warning that the drug should never be discontinued before the patient discusses the situation with a physician. Stopping the drug could increase the risk of stroke, the FDA warned.

In July, Xarelto received initial approval to reduce a user's risk of blood clots, deep vein thrombosis and pulmonary embolism after replacement surgery of the knee or hip.

The drug is marketed by Janssen Pharmaceuticals, based in Titusville, N.J.

More information

To learn more about atrial fibrillation, visit the U.S. National Heart Lung and Blood Institute.

Copyright © 2011 HealthDay. All rights reserved.

Previous: Vitamin D Lacking in Many Spine Surgery Patients Next: Buyer, Beware of Over-the-Counter Thyroid Supplements: Study

Reader comments on this article are listed below. Review our comments policy.

Submit your opinion:





Remember my personal information

Notify me of follow-up comments?


Useful Sites
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2016
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.