Create Account | Sign In: Author or Forum

News  |  Journals  |  Conferences  |  Opinion  |  Articles  |  Forums  |  Twitter    
Category: Family Medicine | Neurology | Research | Rheumatology | News

Back to Health News

Researchers ID Gene for Neck Disorder

Last Updated: March 09, 2012.

Cervical dystonia is a painful condition in which the neck muscles force the head to move involuntarily.


Cervical dystonia is a painful condition in which the neck muscles force the head to move involuntarily

Share |

Comments: (0)




FRIDAY, March 9 (HealthDay News) -- The first gene linked to an often painful neck disorder has been identified by researchers.

Adult-onset primary cervical dystonia, which is characterized by involuntary twisting of the neck, occurs in about 30 of every 100,000 people, previous research has reported.

In this new study, researchers conducted a genetic analysis of a patient with the condition, his identical twin whose neck also twisted and family members, some of whom also had the disorder. The investigators pinpointed a mutation in the CIZ1 gene, which produces a protein expressed in certain nerve cells in the brain and appears to be involved in cell cycle activities.

However, the researchers did not identify the cellular mechanism associated with cervical dystonia.

The study findings were released online in advance of publication in an upcoming print issue of the Annals of Neurology.

While the researchers believe that CIZ1 is one genetic cause of the disorder, it's likely that other genes linked to cervical dystonia will be found, according to Dr. Ryan Uitti, a neurologist at the Mayo Clinic in Jacksonville, Fla.

There are a number of treatments for cervical dystonia. The most common is botulinum toxin injections, which incapacitate the nerve in the affected muscle and eliminate chronic pain and muscle pulling/contraction.

But some people with the condition don't realize that it is unusual and that they should seek medical help, Uitti noted.

"They think they slept wrong at some point, or, because the twisting might straighten out with another maneuver, such as walking backwards, they might actually [not be taken seriously]," Uitti said in a Mayo Clinic news release.

More information

We Move has more about cervical dystonia.

SOURCE: Mayo Clinic, news release, March 5, 2012

Copyright © 2012 HealthDay. All rights reserved.

Previous: EKG Testing May Spot Fatal Heart Conditions in Children Next: One in Four HIV Patients Has Long Gaps Between Doctor's Visits: Study

Reader comments on this article are listed below. Review our comments policy.

Submit your opinion:





Remember my personal information

Notify me of follow-up comments?


Useful Sites
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2016
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.