Create Account | Sign In: Author or Forum

 
 
News  |  Journals  |  Conferences  |  Blogs  |  Articles  |  Forums  |  Twitter    
 

 Headlines:

 

Category: Oncology | Pharmacy | FDA Approvals

Back to Health News

Votrient Approved to Treat Cancer That Begins in Soft Tissue

Last Updated: April 27, 2012.

 

Drug inhibits process that fuels tumor growth

Share |

Comments: (0)

Tell-a-Friend

 

  Related
 

FRIDAY, April 27 (HealthDay News) -- Votrient (pazopanib) has been approved by the U.S. Food and Drug Administration to treat people with soft tissue sarcoma that have received previous chemotherapy.

This type of tumor originates in soft tissue such as a muscle, fat, or fibrous tissue, the agency said in a news release. About 10,000 cases of soft tissue sarcoma are reported each year in the United States.

Votrient works by inhibiting angiogenisis, the production of new blood vessels that fuel tumor growth. The drug's safety and effectiveness were evaluated in clinical studies involving 369 people with soft tissue sarcoma who had undergone chemotherapy. Among people who took Votrient, the disease didn't progress for an average of 4.6 months, compared to 1.6 months among people who took an inactive placebo.

The most common side effects of Votrient included fatigue, diarrhea, nausea, weight loss, high blood pressure and decreased appetite. The drug's label will carry a "black box" warning of the potential for severe liver damage, which could be fatal. People who are given the drug should have their liver function monitored, the agency said.

Votrient was first approved in October 2009 to treat advanced kidney cancer. The drug is marketed by GlaxoSmithKline, based in Research Triangle Park, N.C.

More information

Medline Plus has more about this drug.

Copyright © 2012 HealthDay. All rights reserved.


Previous: Afinitor Approval Expanded to Include Benign Kidney Tumors Next: Animals More Interesting to Kids Than Toys, Study Shows

Reader comments on this article are listed below. Review our comments policy.


Submit your opinion:

Name:

Email:

Location:

URL:

Remember my personal information

Notify me of follow-up comments?

advertisement.gif (61x7 -- 0 bytes)
 

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

 
     

 advertisement.gif (61x7 -- 0 bytes)

 

 

Useful Sites
MediLexicon
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2014
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Advertising
Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.