Create Account | Sign In: Author or Forum

 
 
News  |  Journals  |  Conferences  |  Blogs  |  Articles  |  Forums  |  Twitter    
 

 Headlines:

 

Category: Nephrology | Diabetes | News

Back to Health News

Tight Blood-Sugar Control Shows Mixed Results for Health of Kidneys: Study

Last Updated: May 29, 2012.

 

The approach might ease certain signs of kidney damage in diabetics, but longer-term benefit unclear

Share |

Comments: (0)

Tell-a-Friend

 

  Related
 
The approach might ease certain signs of kidney damage in diabetics, but longer-term benefit unclear.

TUESDAY, May 29 (HealthDay News) -- Intensive control of blood sugar levels reduces the risk of certain signs of kidney damage among diabetics, new research indicates.

However, the evidence did not show that intensive control lowers the risk of actually developing severe kidney disease.

The two signs of kidney damage that the study focused on are conditions known as microalbuminuria and macroalbuminuria. These are characterized by excessive levels of protein in the urine, usually resulting from damage to the filtering units of the kidneys, according to background information in the study published May 28 in the Archives of Internal Medicine.

But, the review of data from seven clinical trials that included more than 28,000 adult patients did not find conclusive evidence that intensive blood-sugar control was related to a reduced risk of serious kidney problems, including kidney failure or death from kidney failure.

"Our analysis demonstrates that, after 163,828 patient-years of follow-up in the seven studies examined, intensive glycemic [blood sugar] control lessens albuminuria," but there's not enough data to say if that benefit extends to kidney disease or kidney failure, wrote Dr. Steven Coca, of Yale University, and colleagues.

This may mean that there's little point to beginning intensive blood-sugar control in the mid-stage of type 2 diabetes in an attempt to prevent kidney failure, they concluded.

However, an expert not involved in the study says the studies included in this meta-analysis were too short to assess how intensive blood-sugar control might affect the risk of kidney failure in patients with type 2 diabetes.

"Although implementing intensive therapy is difficult and imposes burden and expense, all of the primary data continue to support its long-term benefit," Dr. David Nathan, of Massachusetts General Hospital, wrote in an accompanying editorial.

Another expert agreed.

"I feel this [finding] is misleading since most of the studies included in the analysis had relatively short durations of 'intensive' treatment and also fairly short durations of follow-up," said Dr. Tracy Breen, director of diabetes care at North Shore-LIJ Health System in New Hyde Park, N.Y.

She added that "microvascular complications often take many years to develop - any analysis that includes trials with less than 10 years of follow-up may not have the statistical power to show difference in clinical events."

More information

The American Diabetes Association has more about tight diabetes control.

SOURCE: Tracy Breen, M.D., director, diabetes care, North Shore-LIJ Health System, New Hyde Park, N.Y.; Archives of Internal Medicine, news release, May 28, 2012

Copyright © 2012 HealthDay. All rights reserved.


Previous: Education May Protect Brain From Exposure to Solvents Next: Health Highlights: May 29, 2012

Reader comments on this article are listed below. Review our comments policy.


Submit your opinion:

Name:

Email:

Location:

URL:

Remember my personal information

Notify me of follow-up comments?

advertisement.gif (61x7 -- 0 bytes)
 

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

 
     

 advertisement.gif (61x7 -- 0 bytes)

 

 

Useful Sites
MediLexicon
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2014
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Advertising
Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.