Here are what the editors at HealthDay consider to be the most important developments in Urology for April 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Surveillance Feasible for Small Testicular Masses
THURSDAY, April 29 (HealthDay News) -- In men with incidental testicular masses less than 1 cm in size, ultrasound surveillance may be a safe alternative to immediate surgical removal, according to a study published in the April issue of The Journal of Urology.
Provenge Approved for Advanced Prostate Cancer
THURSDAY, April 29 (HealthDay News) -- Provenge (sipuleucel-T), a therapy designed to boost the immune system's ability to combat prostate cancer, has been approved by the U.S. Food and Drug Administration.
Statin Use May Lower Risk of Prostate Cancer Recurrence
THURSDAY, April 29 (HealthDay News) -- In men treated with radiotherapy for prostate cancer, statin use is associated with significant improvements in clinical outcomes, including a higher likelihood of relapse-free survival, according to research published online April 26 in the Journal of Clinical Oncology.
ECE: Testosterone, ED Tied to Higher Cardiac Mortality Risk
WEDNESDAY, April 28 (HealthDay News) -- Low testosterone levels in men with erectile dysfunction (ED) are associated with an increased risk of dying of cardiovascular disease, according to a study presented at the European Congress of Endocrinology, held from April 24 to 28 in Prague, Czech Republic. A study by the same researchers also presented at the meeting found that impaired penile blood flow is linked to an increased risk of cardiovascular disease in obese men with ED more than in leaner men with the condition.
Four-Kallikrein Panel Could Reduce Prostate Biopsies
WEDNESDAY, April 28 (HealthDay News) -- As has been reported previously, in men with elevated prostate-specific antigen (PSA), a panel of four kallikrein forms in serum -- total, free and intact PSA, and kallikrein-related peptidase 2 (hK2) -- may predict the result of biopsy and help reduce unnecessary biopsy rates, according to a replication study published online April 26 in the Journal of Clinical Oncology.
Risk Factors for Physician Misconduct Identified
WEDNESDAY, April 28 (HealthDay News) -- Doctors who are male, are from lower socioeconomic groups or had academic difficulties in medical school may be at increased risk of professional misconduct, according to a study published online April 27 in BMJ.
FDA Changes Medical Device Advisory Committee Process
TUESDAY, April 27 (HealthDay News) -- Because of the increasing number of medical device advisory panel meetings in recent years, the U.S. Food and Drug Administration is changing the way expert panels review and discuss information during public hearings on devices that are being reviewed for premarket approval.
Interruptions Increase Medication Errors by Nurses
TUESDAY, April 27 (HealthDay News) -- Nurses who are interrupted in the process of preparing and administering medications are more likely to make an error, with error severity increasing with the number of interruptions, according to a study in the April 26 issue of the Archives of Internal Medicine.
Financial Ties Negatively Affect Perceptions of Research Quality
TUESDAY, April 27 (HealthDay News) -- Disclosure of financial ties to industry influences patients', physicians', and research participants' beliefs about the quality of research evidence, according to a review published in the April 26 issue of the Archives of Internal Medicine.
Most Doctors Not Knowledgeable About Herbals
MONDAY, April 26 (HealthDay News) -- Most physicians are not knowledgeable about herbal medicines and believe the general public is poorly informed as well, according to the results of a survey published in the April issue of the Drug and Therapeutics Bulletin.
Socioeconomic Status Affects Prostate Cancer Treatment
FRIDAY, April 23 (HealthDay News) -- In men with prostate cancer, lower socioeconomic status is associated with a significantly lower likelihood of undergoing radical prostatectomy or radiotherapy, according to a study published April 22 in BMJ.
Urologist Presence Linked to Less Urologic Cancer Mortality
THURSDAY, April 22 (HealthDay News) -- The presence of a urologist in a county is linked to lower mortality for prostate, bladder and kidney cancer, though increasing urologist density beyond two urologists per 100,000 people does not result in further improvements, according to research published online April 20 in the Journal of Clinical Oncology.
In Men With ED, Statins Linked to Hypogonadism
FRIDAY, April 16 (HealthDay News) -- Observations of men with erectile dysfunction suggest that statin therapy may lead to overt primary hypogonadism, which should be considered when evaluating testosterone levels in these patients, according to research published in the April issue of the Journal of Sex Medicine.
Drug Beneficial in Castration-Resistant Prostate Cancer
THURSDAY, April 15 (HealthDay News) -- In men with progressive, metastatic, castration-resistant prostate cancer, the new treatment MDV3100 -- an androgen-receptor antagonist -- has shown promising antitumor activity, according to a study published online April 15 in The Lancet.
Prostate Cancer Linked to Thromboembolism
WEDNESDAY, April 14 (HealthDay News) -- Prostate cancer patients -- especially those receiving endocrine therapy -- have an increased risk of thromboembolism, according to a study published online April 14 in The Lancet Oncology.
Regional Variations Seen in Radical Prostatectomy Cost
THURSDAY, April 8 (HealthDay News) -- Even after adjustment for medical case mix, local wages and other factors, there are wide variations from state to state in the total cost of radical prostatectomy, suggesting that inefficiencies exist in the health care market, according to research published in the April issue of The Journal of Urology.
Testis Cancer Survivors Likely to Have Poor Health Habits
TUESDAY, April 6 (HealthDay News) -- Testis cancer survivors may be likely to engage in harmful health behaviors such as binge drinking and skimping on fruits and vegetables, according to a study published online April 5 in the Journal of Clinical Oncology.
Therapy Found Effective for Overactive Bladder Syndrome
MONDAY, April 5 (HealthDay News) -- In patients with overactive bladder syndrome, percutaneous tibial nerve stimulation therapy may be safe and effective, according to a study in the April issue of The Journal of Urology.
Pediatric Vesicoureteral Reflux Treatment Studies Faulted
MONDAY, April 5 (HealthDay News) -- The overall per-ureter dextranomer/hyaluronic acid success rate in patients with pediatric vesicoureteral varies widely between studies, and this variation can't be explained by most underlying patient or study factors, suggesting a need for more study and improved reporting of vesicoureteral reflux treatment, according to a review published online April 5 in Pediatrics.
Testicular Size Discrepancy Linked to Varicocele Presence
THURSDAY, April 1 (HealthDay News) -- In infertile men, testicular size discrepancy is nearly twice as prevalent in those with a varicocele than in those without a varicocele, and a smaller left testicle is more common than a smaller right testicle, according to a study published in the March issue of Urology.
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