Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for May 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Early Antibiotics in COPD Hospitalizations Beneficial
TUESDAY, May 25 (HealthDay News) -- Chronic obstructive pulmonary disease (COPD) patients hospitalized for exacerbations of their illness who receive antibiotic treatment within the first two days of their hospitalization fare better than those who do not, according to research published in the May 26 issue of the Journal of the American Medical Association.
β-Blockers May Be Beneficial in Treating COPD
MONDAY, May 24 (HealthDay News) -- Chronic obstructive pulmonary disease (COPD) patients taking β-blockers may have a decreased risk of exacerbations, as well as a decreased mortality risk, according to research published in the May 24 issue of the Archives of Internal Medicine.
Erlotinib Significantly Improves Survival in Advanced NSCLC
FRIDAY, May 21 (HealthDay News) -- Maintenance therapy with erlotinib for patients with advanced non-small-cell lung cancer given immediately after initial chemotherapy is well-tolerated and significantly prolongs progression-free survival, according to research published online May 20 in The Lancet Oncology.
Muscle Fatigue Linked to Decreased Postural Stability
THURSDAY, May 20 (HealthDay News) -- Patients with no low back pain who have had inspiratory muscles fatigue (IMF) use a postural control strategy similar to that of patients with low back pain, resulting in decreased postural stability and suggesting that IMF might have a role in the high recurrence rate of low back pain (LBP), according to research published in the May 1 issue of Spine.
Botox Injections Resolve Chronic Cough
THURSDAY, May 20 (HealthDay News) -- Injection with botulinum toxin type A (BtxA) can resolve chronic cough caused by laryngeal hypertonicity and neuroplastic changes, according to research published in the May issue of the Archives of Otolaryngology -- Head & Neck Surgery.
Antibiotic Resistance May Persist Months After Treatment
WEDNESDAY, May 19 (HealthDay News) -- After a course of antibiotics for respiratory or urinary tract infection, an individual is likely to develop resistance to the antibiotic that may persist for up to 12 months, according to research published online May 18 in the BMJ.
TB Global Fight Still Has a Way to Go
WEDNESDAY, May 19 (HealthDay News) -- Even though 36 million people worldwide were cured of tuberculosis and 6 million lives were saved between 1995 and 2008, the disease still takes a substantial toll and long-term goals for its eradication may not be met, according to a paper published online May 19 in The Lancet, the first in a series of papers on tuberculosis.
Sildenafil of Mixed Value in Idiopathic Pulmonary Fibrosis
TUESDAY, May 18 (HealthDay News) -- In patients with advanced idiopathic pulmonary fibrosis, treatment with sildenafil does not significantly increase walking distance compared to placebo but may be associated with some symptomatic improvements, according to a study published online May 18 in the New England Journal of Medicine to coincide with presentation at the American Thoracic Society (ATS) International Conference in New Orleans.
CPAP Found Feasible for Extremely Preterm Infants
MONDAY, May 17 (HealthDay News) -- In extremely preterm infants, early treatment with continuous positive airway pressure (CPAP) may be a viable alternative to early treatment with intubation and surfactant, according to a study published online May 16 in the New England Journal of Medicine to coincide with presentation at the annual meeting of the American Thoracic Society, held from May 14 to 19 in New Orleans. The study also found that a lower target range of oxygen saturation does not reduce a composite of severe retinopathy or death and may be associated with increased mortality.
Many General Internists Leave Field by Mid-Career
FRIDAY, May 14 (HealthDay News) -- Roughly one out of six general internists are leaving internal medicine by mid-career, a substantially higher proportion compared to internal medicine subspecialists, according to survey results published April 29 in the Journal of General Internal Medicine.
FDA and GE Issue Class I Recall of Anesthesia Systems
THURSDAY, May 13 (HealthDay News) -- The U.S. Food and Drug Administration and GE Healthcare have alerted health care professionals of a Class I recall of specific lots of Aisys and Avance Anesthesia Systems due to a defect in the control board wiring harnesses.
Maternal Vitamin A Improves Offspring's Lung Function
WEDNESDAY, May 12 (HealthDay News) -- Maternal vitamin A supplementation before, during, and after pregnancy in an undernourished population appears to result in improved lung function in offspring, according to a study reported in the May 13 issue of the New England Journal of Medicine.
New FDA Program Targets Misleading Drug Advertising
WEDNESDAY, May 12 (HealthDay News) -- The U.S. Food and Drug Administration has announced the launch of a new program to educate health care providers regarding their role in making certain that advertisements and promotions for prescription drugs are truthful and not misleading.
COPD Exacerbations May Raise Risk of Cardiovascular Events
TUESDAY, May 11 (HealthDay News) -- Exacerbations of chronic obstructive pulmonary disease (COPD) appear to increase the risk of myocardial infarction (MI) and stroke, according to research published in the May issue of Chest.
AHA Cites New Evidence for Air Pollution's Role in Heart Events
MONDAY, May 10 (HealthDay News) -- Exposure to particulate matter (PM) less than 2.5 µm in diameter (PM2.5) has a causal role in cardiovascular morbidity and mortality, even if the exposure is not long term, and it is a modifiable risk factor, according to an update to an American Heart Association scientific statement published online May 10 in Circulation.
Bronchoscopy Skills Acquired Faster With Simulation Training
MONDAY, May 10 (HealthDay News) -- The rate at which bronchoscopy skills are learned can be enhanced by certain educational interventions, and these skills can be evaluated via performance-based metrics, according to research published in the May issue of Chest.
Pneumococcal Vaccine Not Found to Reduce Heart Risks
TUESDAY, May 4 (HealthDay News) -- In older men, receipt of pneumococcal vaccine is not linked to a reduced risk of acute myocardial infarction (MI) and stroke, according to a study in the May 5 issue of the Journal of the American Medical Association.
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