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Category: Family Medicine | Monthly Briefing

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June 2010 Briefing - Family Practice

Last Updated: July 01, 2010.

 

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Here are what the editors at HealthDay consider to be the most important developments in Family Practice for June 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Group of Older Men Have Cardio Events With Testosterone Gel

WEDNESDAY, June 30 (HealthDay News) -- Older men with limited mobility have improved muscle strength but an increased risk of cardiovascular events when they receive testosterone gel supplementation, according to research published online June 30 in the New England Journal of Medicine.

Abstract
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Cardio Exercise Safe, Beneficial in Rheumatoid Arthritis

WEDNESDAY, June 30 (HealthDay News) -- Cardiorespiratory aerobic exercise is safe for rheumatoid arthritis (RA) patients and leads to improved function and quality of life, though its effect is small, according to a meta-analysis published in the July issue of Arthritis Care & Research.

Abstract
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Expectant, New Moms Uninformed on Preterm Birth

WEDNESDAY, June 30 (HealthDay News) -- Most new or expectant moms have not discussed the possibility of preterm birth with their health care providers, despite the fact that one in eight babies born every year is preterm, according to the results of a survey conducted by the March of Dimes and BabyCenter.

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Overweight Linked to Cancer Mortality in Asia-Pacific Region

WEDNESDAY, June 30 (HealthDay News) -- Overweight and obese individuals in groups across the Asia-Pacific region have a higher risk of death from cancer than normal-weight individuals in the region, according to research published online June 30 in The Lancet Oncology.

Abstract
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Editorial (subscription or payment may be required)

Many Breast Cancer Patients Don't Adhere to Therapy

WEDNESDAY, June 30 (HealthDay News) -- Only half of hormone-sensitive stage I to III breast cancer patients prescribed adjuvant hormonal therapy adhere to that therapy for the full duration at the optimal schedule, and younger women in particular are at high risk of non-adherence, according to a study published online June 28 in the Journal of Clinical Oncology.

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Children's Language Skills Tied to Later Psychosocial Effects

WEDNESDAY, June 30 (HealthDay News) -- Early receptive language skills have a significant association with adult mental health and psychosocial adjustment, according to a study published online June 29 in Pediatrics.

Abstract
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Benzoyl Peroxide/Salicylic Acid Wins As Initial Acne Treatment

WEDNESDAY, June 30 (HealthDay News) -- Benzoyl peroxide (BPO) with salicylic acid (SA) works better than BPO with clindamycin (CL) for the initial treatment of acne, but after 10 to 12 weeks there is little difference in results between the two treatments, according to research published in the July issue of the Journal of the American Academy of Dermatology.

Abstract
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Adult Obesity Rate Increases in 28 States

WEDNESDAY, June 30 (HealthDay News) -- In the past year, the adult obesity rate increased in 28 states, and there are marked differences in obesity rates by region, race, and income, according to a report published June 29 by the Trust for America's Health and the Robert Wood Johnson Foundation.

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Family-Centered Rounds Are Popular, Well-Perceived

WEDNESDAY, June 30 (HealthDay News) -- Family-centered rounds (FCRs) are the most common pediatric hospital rounding method, lead to better communication, and do not extend the duration of rounding time, according to research published online June 29 in Pediatrics.

Abstract
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Generic Effexor XR Approved

TUESDAY, June 29 (HealthDay News) -- The first generic version of Effexor extended release capsules (venlafaxine hydrochloride) to treat major depressive disorder has been approved by the U.S. Food and Drug Administration.

National Library of Medicine

MMRV Vaccine Ups Fever and Seizure Risk

TUESDAY, June 29 (HealthDay News) -- Measles-mumps-rubella-varicella (MMRV) vaccination is associated with an increased risk of fever and seizure in young children, above that already associated with measles-containing vaccines, according to research published online June 29 in Pediatrics, confirming preliminary evidence from a previous study.

Abstract
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Mammograms for Poor Insured Rise With Stepwise Reminders

TUESDAY, June 29 (HealthDay News) -- A stepwise screening mammogram reminder program significantly increases the likelihood that an insured, very low-income woman will obtain a mammogram, according to research published online June 29 in Cancer Epidemiology, Biomarkers & Prevention.

Abstract
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Maternal Smoking May Impact Child's Mental Health

TUESDAY, June 29 (HealthDay News) -- Maternal smoking may have an intrauterine effect on child conduct and externalizing problems, and there may be a biologically mediated association between paternal smoking and increased childhood body mass index (BMI), according to two studies published online June 29 in Pediatrics.

Abstract - Brion
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Abstract - Kwok
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Editorial (subscription or payment may be required)

Lower CYP2C19 Function Plus Clopidogrel May Cause Harm

TUESDAY, June 29 (HealthDay News) -- Patients treated with clopidogrel who are carriers of the loss-of-function CYP2C19*2 allele may be at increased risk for cardiovascular events and death, according to research published in the July 6 issue of the Journal of the American College of Cardiology.

Abstract
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Collegial Atmosphere Promotes Effective Child Protection Team

TUESDAY, June 29 (HealthDay News) -- Hospital-based child protection teams (CPT) are most effective when working within a collegial, multidisciplinary environment, according to research published online June 29 in Pediatrics.

Abstract
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Diagnostic Adverse Events Usually Due to Human Failure

TUESDAY, June 29 (HealthDay News) -- Diagnostic adverse events (DAEs) are most often caused by human error, and their consequences are more severe than those of other types of adverse events, according to research published in the June 28 issue of the Archives of Internal Medicine.

Abstract
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Invited Commentary (subscription or payment may be required)

14 Percent of Cancer Survivors Live With Minor Children

TUESDAY, June 29 (HealthDay News) -- Nationwide, an estimated 1.58 million cancer survivors live with their minor children, representing a large number of families who confront special challenges and may need additional support, according to research published online June 28 in Cancer.

Abstract
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Editorial

Statins May Slow Post-Surgery Cancer Recurrence

TUESDAY, June 29 (HealthDay News) -- In men who undergo radical prostatectomy for prostate cancer, those who take statins have a decreased risk of biochemical recurrence, according to research published online June 28 in Cancer.

Abstract
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End-of-Life Hospital Care Has Room for Improvement

TUESDAY, June 29 (HealthDay News) -- In U.S. hospitals, the care of patients at end of life nearly always includes close attention to pain management and efforts to ease breathing, but there are other areas of care that need improvement, according to research published in the June 28 issue of the Archives of Internal Medicine.

Abstract
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New Guidelines Issued for Clopidogrel After FDA Warning

TUESDAY, June 29 (HealthDay News) -- The American College of Cardiology Foundation (ACCF) and the American Heart Association (AHA) released a joint clinical alert on June 28 to guide physicians in the interpretation of the boxed warning recently placed on the antiplatelet drug clopidogrel (Plavix) by the U.S. Food and Drug Administration. The full text of the alert will be co-published online June 28 in the Journal of the American College of Cardiology and Circulation.

Full Text - JACC
Full Text - Circulation

Statins May Not Help High-Risk Patients With No CVD History

MONDAY, June 28 (HealthDay News) -- Statins do not appear to be associated with a reduced risk of death in people who are at increased risk for cardiovascular disease (CVD) but have no history of it, according to research published in the June 28 issue of the Archives of Internal Medicine.

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Doctors Agree Malpractice Fears Drive Overuse of Tests

MONDAY, June 28 (HealthDay News) -- A large majority of physicians agree that the practice of defensive medicine -- stemming from malpractice concerns -- is responsible for an overuse of medical tests and procedures, according to a research letter in the June 28 issue of the Archives of Internal Medicine.

Abstract
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AHA Releases Guide for Cardiopulmonary Exercise Tests

MONDAY, June 28 (HealthDay News) -- In response to the increasing clinical value of cardiopulmonary exercise testing (CPX), the American Heart Association has developed the Clinician's Guide to Cardiopulmonary Exercise Testing in Adults to complement existing exercise testing guidelines with details on CPX. The new guide is being released as a scientific statement and published online June 28 in Circulation.

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Two Studies Demonstrate Cardiac Risks of Rosiglitazone

MONDAY, June 28 (HealthDay News) -- New evidence suggests that rosiglitazone is associated with an increased risk of adverse cardiovascular outcomes, according to two studies published online June 28 in the Journal of the American Medical Association and the Archives of Internal Medicine. The studies were released online ahead of publication because of their relevance to an upcoming U.S. Food and Drug Administration meeting intended to review the safety of rosiglitazone.

Abstract - Graham
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Editorial
Abstract - Nissen/Wolski
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American Heart Association Comment

Teen Girls More Likely to View Drug, Alcohol Use Positively

MONDAY, June 28 (HealthDay News) -- Teenage girls are more likely than their male counterparts to perceive potential benefits -- including "self-medicating" benefits -- from drug and alcohol use, according to survey data released by the Partnership for a Drug-Free America and the MetLife Foundation.

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Venous Thromboembolism Risk Factors Vary by Race

MONDAY, June 28 (HealthDay News) -- Black Americans with venous thromboembolism (VTE) are less likely to have commonly recognized transient risk factors for the condition, are more likely to have cardiovascular disease risk factors, and are more likely to progress to pulmonary embolism than are white Americans, according to research published in the July issue of the American Journal of Hematology.

Abstract
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Editorial (subscription or payment may be required)

Spinal Kinematics Unlikely Marker for Teen Back Pain

FRIDAY, June 25 (HealthDay News) -- Spinal kinematics may not effectively distinguish adolescents with nonspecific chronic low back pain (NSCLBP) from their pain-free counterparts unless those with NSCLBP are subclassified, according to a study in the June 15 issue of Spine.

Abstract
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Digoxin May Increase Mortality Risk in Hemodialysis Patients

FRIDAY, June 25 (HealthDay News) -- Digoxin use by patients on hemodialysis is linked to increased mortality, particularly in patients who have low pre-dialysis potassium concentrations, according to research published online June 24 in the Journal of the American Society of Nephrology.

Abstract
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Maternal Homocysteine Does Not Predict Low Birth Weight

FRIDAY, June 25 (HealthDay News) -- Maternal levels of homocysteine and related B vitamins in late pregnancy have no association with birth weight, according to a study in the June issue of the American Journal of Obstetrics & Gynecology.

Abstract
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Statins May Lower Risk of Atrial Fibrillation in Heart Patients

FRIDAY, June 25 (HealthDay News) -- Statin therapy is associated with a reduced risk of developing atrial fibrillation (AF) among coronary artery disease patients, and lipid-lowering therapy (LLT) appears to reduce the risk of death and cardiovascular events among individuals who already have AF, according to research published in the June 15 issue of the American Journal of Cardiology.

Abstract - Kulik
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Abstract - Badheka
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Updated Recommendations for Endometriosis Released

FRIDAY, June 25 (HealthDay News) -- Women who suffer from endometriosis-related pain should be treated first with conservative, non-surgical approaches and then with more invasive options if pain does not resolve, and hysterectomy only as a last resort, according to a practice bulletin issued by the American College of Obstetricians and Gynecologists (ACOG) and published in the July issue of Obstetrics & Gynecology.

Abstract
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Substantial Proportion of STI Consultations Involve Swingers

FRIDAY, June 25 (HealthDay News) -- Swingers -- heterosexuals who practice mate swapping or group sex or visit sex clubs as couples -- make up a considerable proportion of consultations for sexually transmitted infections (STIs) and should be identified and treated as a risk group for STI prevention and care services, according to research published online June 24 in Sexually Transmitted Infections.

Abstract
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Recent Low Back Pain Guidelines Offer Similar Advice

FRIDAY, June 25 (HealthDay News) -- Recent clinical practice guidelines offer similar recommendations for assessing and managing low back pain, and clinicians can improve patient care by adopting these recommendations, according to a review published in the June issue of The Spine Journal.

Abstract
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Moldy Homes Linked to Higher Risk of Severe Asthma Attacks

FRIDAY, June 25 (HealthDay News) -- High mold exposure in the home may lead to an increased risk of severe asthma attacks among children with variants in the chitinase gene CHIT1, according to research published online June 10 in the American Journal of Respiratory and Critical Care Medicine.

Abstract
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Active Surveillance Sound Approach to Prostate Cancer

FRIDAY, June 25 (HealthDay News) -- Active surveillance appears to be a sound approach to managing prostate cancer with a favorable risk profile, according to a review published in the July issue of The Journal of Urology.

Abstract
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Panel Urges Two Yearly Preventive Visits for Teens

FRIDAY, June 25 (HealthDay News) -- Adolescent girls may require two "well-child" visits annually -- one general preventive visit and one dedicated to reproductive health, and both visits should be covered by health insurance, according a committee opinion of the American College of Obstetricians and Gynecologists (ACOG) published in the July issue of Obstetrics & Gynecology.

Abstract
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Only 1 in 10 Meets '05 Sodium Intake Recommendations

THURSDAY, June 24 (HealthDay News) -- Only one in 10 American adults adheres to the 2005 recommendation for daily sodium intake, according to a report published in the June 25 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Dulera Inhaler Approved for Asthma

THURSDAY, June 24 (HealthDay News) -- Merck & Co.'s Dulera inhaler has been approved for people 12 and older whose asthma isn't controlled with other medication, the company said Thursday in a news release.

FDA

Rate of HIV Testing Up, New AIDS Cases Down in D.C.

THURSDAY, June 24 (HealthDay News) -- In Washington, D.C., where the HIV case rate is nearly 10 times the U.S. rate, the proportion of the population tested for HIV has increased and the rate of newly diagnosed AIDS cases has decreased in recent years, according to a report published in the June 25 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

Full Text - D.C. Report
Full Text - Rhode Island Report

Phone Reminders Up Colorectal Cancer Screening Rate

THURSDAY, June 22 (HealthDay News) -- An automated telephone intervention appears to increase the completion of fecal occult blood testing (FOBT) for colorectal cancer screening, according to a study published in the July issue of Medical Care.

Abstract
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Cytology Limits Seen in Low-Risk Patients With Hematuria

THURSDAY, June 24 (HealthDay News) -- During evaluation of low-risk patients with asymptomatic microscopic hematuria (AMH), voided urine cytology is associated with a substantial cost without providing a diagnostic benefit, according to research published in the June issue of Urology.

Abstract
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Editorial 1 (subscription or payment may be required)
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Editorial 2 (subscription or payment may be required)
Reply 2 (subscription or payment may be required)

Computerized Decision Support Boosts Postpartum Vaccination

THURSDAY, June 24 (HealthDay News) -- A computer-based clinical decision-support algorithm can dramatically increase rates of tetanus, diphtheria, and acellular pertussis (Tdap) vaccination of postpartum women, according to a study in the July issue of Obstetrics & Gynecology.

Abstract
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Parents Divided Over Genetic Testing of Minors for Cancer

THURSDAY, June 24 (HealthDay News) -- Genetic testing of minors for adult hereditary cancer syndromes is not currently recommended, and parents' opinions on testing of minors for BRCA1/2 mutations are divided, according to research published online June 21 in the Journal of Clinical Oncology.

Abstract
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Many Psoriasis Sufferers Hindered by Insurance Issues

THURSDAY, June 24 (HealthDay News) -- A third of people with psoriasis do not receive adequate treatment for their condition because they lack adequate health care coverage or are unable to meet the copays for treatment, according to results of a survey conducted by the National Psoriasis Foundation.

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Underinsured African-Americans With Breast Cancer Fare Worse

THURSDAY, June 24 (HealthDay News) -- Underinsured African-American patients are more likely to experience poorer breast cancer-specific survival than their non-Hispanic white counterparts, though the effect of race on survival is not statistically significant after adjustment for sociodemographic and clinical factors, according to research published online June 23 in the Journal of the National Cancer Institute.

Abstract
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Excess Gestational Weight Gain Linked to Long-Term Issues

THURSDAY, June 24 (HealthDay News) -- Gaining an excessive amount of weight during pregnancy may have long-term effects on mothers' and children's body sizes, but the benefits of lower gains should be balanced against the risk of small-for-gestational-age (SGA) births, according to research published in the June issue of the American Journal of Obstetrics & Gynecology.

Abstract
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Test Combination Predicts Fall Risk in Parkinson's Disease

WEDNESDAY, June 23 (HealthDay News) -- A combination of tests on disease-specific and mobility- and balance-related measures can accurately predict which Parkinson's disease patients are more likely to fall, according to a study published online June 23 in Neurology.

Abstract
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Editorial (subscription or payment may be required)

U.S. Ranks Last in International Health Care Survey

WEDNESDAY, June 23 (HealthDay News) -- Of seven wealthy countries, the United States ranks last in health care, according to the 2010 edition of "Mirror, Mirror on the Wall," a report on the quality of international care released June 23 by The Commonwealth Fund.

Overview
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New 2009 H1N1 Influenza Virus Test Authorized by FDA

WEDNESDAY, June 23 (HealthDay News) -- The U.S. Food and Drug Administration has authorized a new test that uses molecular biology techniques to diagnose 2009 H1N1 influenza virus infection in humans.

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Health Professionals Often Do Little to Help Smokers Quit

WEDNESDAY, June 23 (HealthDay News) -- Many health care professionals ask patients about smoking and advise them to quit but do not follow guidelines to help patients actually give up the habit, according to research published online May 27 in Nicotine & Tobacco Research.

Abstract
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Childhood Cancer Risk Not Linked to Cell Tower Exposure

WEDNESDAY, June 23 (HealthDay News) -- The risk of early childhood cancer does not appear to be linked to a mother's exposure to a mobile phone base station during pregnancy, according to a study published June 22 in BMJ.

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Oral Bisphosphonate Use May Reduce Breast Cancer Risk

WEDNESDAY, June 23 (HealthDay News) -- The use of oral bisphosphonates by postmenopausal women appears to significantly reduce the risk of some breast cancers, according to a pair of studies published online June 21 in the Journal of Clinical Oncology.

Abstract - Chlebowski
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Abstract - Rennert
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Editorial

Findings Suggest Harmful Effects From MP3 Players

WEDNESDAY, June 23 (HealthDay News) -- Temporary changes in hearing sensitivity associated with MP3 players suggest that the devices could have potentially harmful effects, according to research published in the June issue of the Archives of Otolaryngology -- Head & Neck Surgery.

Abstract
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C-Section Risk Found High for First-Time Moms Induced at Term

WEDNESDAY, June 23 (HealthDay News) -- Nulliparous women who undergo induced labor at term have double the risk of requiring cesarean delivery, according to a study in the July issue of Obstetrics & Gynecology.

Abstract
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Editorial (subscription or payment may be required)

Weight Control Important for Diabetes Risk in Later Years

TUESDAY, June 22 (HealthDay News) -- In older adults, body fat and weight gain after the age of 50 are associated with a higher risk of diabetes, according to research published in the June 23/30 issue of the Journal of the American Medical Association.

Abstract
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Folic Acid, B12 Do Not Reduce Vascular Events

TUESDAY, June 22 (HealthDay News) -- Supplementation with folic acid and vitamin B12 over an extended period does not have a beneficial effect on vascular outcomes in individuals who have had a myocardial infarction, but it also poses no excess cancer risk, according to a study in the June 23/30 issue of the Journal of the American Medical Association.

Abstract
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Panel Says Ob-Gyn Hospitalist Trend Aids Patients, Doctors

TUESDAY, June 22 (HealthDay News) -- The increasing number of obstetrician-gynecologist hospitalists has the potential to improve patient safety, streamline patient care, and improve the lifestyle of currently practicing Ob-Gyns, according to a committee opinion of the American College of Obstetricians and Gynecologists (ACOG) published in the July issue of Obstetrics & Gynecology.

Abstract
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Surveillance Colonoscopy Can Be Cost-Effective

TUESDAY, June 22 (HealthDay News) -- Surveillance colonoscopy is cost-effective for patients at high risk of colorectal cancer, but aggressive surveillance may be expensive or harmful, according to research published in the June issue of Gastroenterology.

Abstract
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Incidence Rate of Rare Skin Carcinoma on the Rise

TUESDAY, June 22 (HealthDay News) -- The incidence rate (IR) for cutaneous appendageal carcinoma (CAC) in the United States is low and varies by sex/ethnic group, but it has been increasing, possibly partly due to increased ultraviolet exposure and improvements in diagnosis, according to research published in the June issue of the Archives of Dermatology.

Abstract
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Some Moist Toilet Paper Can Cause Severe Reaction

TUESDAY, June 22 (HealthDay News) -- A preservative used in moist toilet paper can cause a severe allergic reaction in some people, as demonstrated by four case reports published online June 21 in the Archives of Dermatology.

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Flame Retardant Affects Thyroid Levels in Pregnant Women

TUESDAY, June 22 (HealthDay News) -- In pregnant women, blood levels of polybrominated diphenyl ether (PBDE) are associated with lower levels of thyroid-stimulating hormone and higher odds of subclinical hyperthyroidism, according to research published online June 21 in Environmental Health Perspectives.

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Post-Heart Attack Drinkers May Fare Better Than Quitters

MONDAY, June 21 (HealthDay News) -- Moderate drinkers who continue to drink after an acute myocardial infarction (AMI) do not appear to experience related adverse effects, and may even have better physical functioning than those who opt to quit drinking alcohol, according to a study in the June 15 issue of the American Journal of Cardiology.

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Breast-Feeding for Six Months Best for Infection Prevention

MONDAY, June 21 (HealthDay News) -- Exclusive breast-feeding until age 6 months is slightly more protective against infectious diseases than exclusive breast-feeding for four months and partially thereafter, according to research published online June 21 in Pediatrics.

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Severe Colitis Reported in Child After Rituximab Treatment

MONDAY, June 21 (HealthDay News) -- Children treated with rituximab for nephrotic syndrome (NS) may be at risk for severe T-cell mediated ulcerative colitis, as demonstrated by a case study published online June 21 in Pediatrics.

Abstract
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PCBs Linked to Reduced Response to Vaccinations

MONDAY, June 21 (HealthDay News) -- Exposure to polychlorinated biphenyls (PCBs) early in life may reduce the effectiveness of childhood vaccinations and impair immune-system responses to infection, according to research published online June 20 in Environmental Health Perspectives.

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Watchful Waiting May Suffice in Low-Risk Prostate Cancer

MONDAY, June 21 (HealthDay News) -- For patients with prostate cancer that has a low risk of progression, active surveillance is associated with a low death rate, suggesting that it may be a sufficient management approach, according to research published online June 18 in the Journal of the National Cancer Institute.

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Rescue Antenatal Steroids Beneficial for Preterm Infants

MONDAY, June 21 (HealthDay News) -- If it has been at least 14 days since an initial dose of antenatal steroids, an additional course of rescue antenatal steroids administered to pregnant women at continued risk of premature delivery can improve their infants' postnatal respiratory function, according to research published in the June issue of the American Journal of Obstetrics & Gynecology.

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Most Pediatricians Admit to 1-2 Diagnostic Errors Per Month

MONDAY, June 21 (HealthDay News) -- Most pediatricians report making at least one to two diagnostic errors per month, and patient harm resulting from these errors is not uncommon, according to research published online June 21 in Pediatrics.

Abstract
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High Tea Consumption Linked to Lower CHD Mortality Risk

FRIDAY, June 18 (HealthDay News) -- Moderate coffee drinkers and moderate to heavy tea drinkers appear to experience less risk of heart disease and, in the case of tea drinkers, lower heart disease-related mortality, according to research published online June 18 in Arteriosclerosis, Thrombosis, and Vascular Biology.

Abstract
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Hepatic Encephalopathy Linked to Chronic Cognitive Effects

FRIDAY, June 18 (HealthDay News) -- Among patients with cirrhosis, episodes of overt hepatic encephalopathy (OHE) may be associated with lingering and cumulative problems with learning, working memory, and response inhibition, according to research published in the June issue of Gastroenterology.

Abstract
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Interest by Physicians Can Play Role in Medication Adherence

FRIDAY, June 18 (HealthDay News) -- Patients whose doctors actively review their medication use and prescribing information are more likely to use inhaled corticosteroids (ICS) for asthma control as prescribed, according to research published online May 31 in the Journal of Allergy and Clinical Immunology.

Abstract
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Low Proportion of Cirrhosis Patients Screened for HCC

FRIDAY, June 18 (HealthDay News) -- Fewer than 20 percent of patients with hepatocellular carcinoma (HCC) who have previously had cirrhosis receive regular screening in the three years before being diagnosed with HCC, and those seeing only primary care doctors are least likely to be screened, according to research published in the July issue of Hepatology.

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ER Visits for Prescription Drug Misuse Climbing

FRIDAY, June 18 (HealthDay News) -- From 2004 to 2008, emergency department visits involving the non-medical use of prescription drugs increased substantially in the United States, according to research published in the June 18 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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10 Risk Factors Associated With Most of Stroke Risk

FRIDAY, June 18 (HealthDay News) -- Worldwide, 10 risk factors are associated with 90 percent of the risk for stroke, suggesting that interventions targeting these particular factors could greatly reduce the stroke burden, according to a study published online June 18 in The Lancet.

Abstract
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Gene Mutation Increases Clot Risk in Women on Tamoxifen

FRIDAY, June 18 (HealthDay News) -- Women taking adjuvant tamoxifen for early-stage breast cancer who develop a thromboembolism (TE) are nearly five times more likely to carry the factor V Leiden (FVL) mutation than women on the medication who don't have a TE, according to a study published online June 16 in the Journal of the National Cancer Institute.

Abstract
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Questionnaire Poorly Predicts Sleep Apnea in Pregnancy

FRIDAY, June 18 (HealthDay News) -- The Berlin questionnaire performs poorly in predicting obstructive sleep apnea (OSA) in pregnant women compared to polysomnography, according to research published in the June issue of the American Journal of Obstetrics & Gynecology.

Abstract
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Sites Contain Graphic Material to Promote Eating Disorders

FRIDAY, June 18 (HealthDay News) -- Pro-eating disorder Web sites are easy to access and contain content that encourages and motivates users to continue their efforts with anorexia and bulimia, though many include recovery-oriented messages as well, according to research published online June 17 in the American Journal of Public Health.

Abstract
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Receipt of Kidney Care Less Likely in Black Communities

FRIDAY, June 18 (HealthDay News) -- Even when their kidney function is clearly declining, people living in communities with a high percentage of black residents are less likely to receive kidney care before they start dialysis than those living elsewhere, regardless of race, according to research published online June 17 in the Journal of the American Society of Nephrology.

Abstract
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Bone Health Supplements Don't Increase Coronary Calcium

FRIDAY, June 18 (HealthDay News) -- Postmenopausal women who take calcium plus vitamin D supplements for bone health do not increase their levels of coronary artery calcium (CAC) and increase their cardiovascular disease risk as a result, according to a study published online June 14 in Menopause.

Abstract
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Lack of Fitness, Inactivity Linked to Walking Falls

FRIDAY, June 18 (HealthDay News) -- Poor physical fitness and physical inactivity may increase the risk of falls while walking, particularly in men, according to research published in the July issue of the American Journal of Preventive Medicine.

Abstract
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EMR Program Benefits More Modest Than Expected

THURSDAY, June 17 (HealthDay News) -- The limited introduction of a central repository for electronic summary care records (SCRs) in England has had a subtle but positive effect on health care delivery, but national implementation will be a complicated process, according to research published June 16 in BMJ.

Abstract
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Colonoscopies Every 1-2 Years Urged for Those at Genetic Risk

THURSDAY, June 17 (HealthDay News) -- Getting surveillance colonoscopies every one to two years instead of every two to three years is associated with a reduced risk of colorectal cancer (CRC) for members of families with Lynch syndrome, according to a study in the June issue of Gastroenterology.

Abstract
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Celecoxib Linked to Lower Rate of Gastrointestinal Events

THURSDAY, June 17 (HealthDay News) -- The cyclooxygenase (COX)-2 selective nonsteroidal anti-inflammatory drug (NSAID) celecoxib is associated with a lower risk of gastrointestinal adverse events than the NSAID diclofenac plus the proton pump inhibitor (PPI) omeprazole in patients with osteoarthritis or rheumatoid arthritis, according to a study published online June 17 in The Lancet.

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Duloxetine Beneficial in Treating Chronic Low Back Pain

THURSDAY, June 17 (HealthDay News) -- Duloxetine appears to significantly reduce pain and improve functioning in nondepressed individuals with non-neuropathic chronic low back pain (CLBP), according to a study published in the June 1 issue of Spine, though during the study, more subjects on duloxetine discontinued treatment because of adverse events than those on placebo.

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Improved Liability Protection Could Up Use of School Grounds

THURSDAY, June 17 (HealthDay News) -- The improvement of liability protection could open public school facilities for recreational activity to the benefit of the larger community, according to a review published in the July issue of the American Journal of Preventive Medicine.

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New Method Gives Better Local Start Date for RSV Prophylaxis

THURSDAY, June 17 (HealthDay News) -- Using five years of local laboratory surveillance data to predict likely respiratory syncytial virus (RSV) outbreak timing is a viable method for recommending optimal immunoprophylaxis dates, according to research published online June 14 in Pediatrics.

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Prenatal Smoking Linked to Pregnancy, Infant Risks

THURSDAY, June 17 (HealthDay News) -- Prenatal smoking continues to be a substantial contributor to infant death in the United States, according to research published in the July issue of the American Journal of Preventive Medicine.

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Psychological Variables Predict Disability From Back Pain

THURSDAY, June 17 (HealthDay News) -- Long-term disability from low back pain (LBP) may be prevented by targeting interventions to several psychological variables, according to research published in the June 1 issue of Spine.

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Later Age at Menarche Tied to Lower Odds of Endometriosis

THURSDAY, June 17 (HealthDay News) -- The risk of endometriosis is lower in women who experience their first period at an older age and higher in women who report an early dysmenorrhea history, according to research published in the June issue of the American Journal of Obstetrics & Gynecology.

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Functional Dyspepsia Tied to Higher Costs for Employees

THURSDAY, June 17 (HealthDay News) -- Individuals with functional dyspepsia are absent from work more often and incur higher direct and indirect medical costs than employees without the condition, according to research published in the June issue of Clinical Gastroenterology and Hepatology.

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