Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for August 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Diverse Veggie Intake May Lower Lung Cancer Risk
TUESDAY, Aug. 31 (HealthDay News) -- Eating a variety of vegetables and fruits may reduce the risk of lung cancer in current smokers, according to research published online Aug. 31 in Cancer Epidemiology, Biomarkers & Prevention.
Genetic Basis for Severe Asthma Identified
MONDAY, Aug. 30 (HealthDay News) -- Interleukin-17A (IL-17A) has been identified as a promoter of severe asthma-like symptoms in mice, a finding that may provide a basis for further research into therapeutic treatments for severe asthma in humans, according to research published online Aug. 29 in Nature Immunology.
Vaccination Coverage Estimate Shrinks With New Method
FRIDAY, Aug. 27 (HealthDay News) -- As the result of a recent change to the method for measuring Haemophilus influenzae serotype b (Hib) vaccination coverage, the proportion of children aged 19 to 35 months considered fully vaccinated has dropped by nearly a third, according to an article published in the Aug. 27 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
CDC's Revised Influenza Death Estimates Show Wide Variation
FRIDAY, Aug. 27 (HealthDay News) -- From 1976 through 2007, the number of annual influenza-related deaths in the United States ranged from 3,349 to 48,614, according to a report published in the Aug. 27 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
Oil Spill Clean-Up Linked to Adverse Respiratory Effects
TUESDAY, Aug. 24 (HealthDay News) -- Individuals participating in the clean-up of a major oil spill may be at higher risk of persistent respiratory symptoms, elevated markers of airway injury, and chromosomal damage, according to a study published online Aug. 23 in the Annals of Internal Medicine.
Low Levels of Tobacco Smoke Exposure Tied to Lung Disease
FRIDAY, Aug. 20 (HealthDay News) -- Individuals exposed to even low levels of tobacco smoke may be at increased risk for developing lung diseases, according to a study published online Aug. 6 in the American Journal of Respiratory and Critical Care Medicine.
Early Palliative Care Beneficial in Metastatic Lung Cancer
WEDNESDAY, Aug. 18 (HealthDay News) -- For patients with metastatic non-small-cell lung cancer, early palliative care is associated with longer survival and improvements in quality of life and mood, according to research published in the Aug. 19 issue of the New England Journal of Medicine.
Estrogen Alone Does Not Increase Lung Cancer Risk
MONDAY, Aug. 16 (HealthDay News) -- Postmenopausal women treated with estrogen alone do not have increased incidence of, or mortality from, lung cancer, according to research published online Aug. 13 in the Journal of the National Cancer Institute.
Simplified Tool Assesses Death Risk in Pulmonary Embolism
WEDNESDAY, Aug. 11 (HealthDay News) -- A simplified version of the Pulmonary Embolism Severity Index (PESI) has clinical utility and prognostic accuracy that is similar to those of the original index, according to a study published in the Aug. 9/23 issue of the Archives of Internal Medicine.
Some Vena Cava Filters Prone to Fracture, Embolization
TUESDAY, Aug. 10 (HealthDay News) -- There is a high rate of fracture and embolization with potentially devastating sequelae associated with two types of Bard filters, according to research published online Aug. 9 in the Archives of Internal Medicine. In addition, the U.S. Food and Drug Administration is recommending that physicians in care of patients with retrievable inferior vena cava filters consider removing the filters as soon as protection from pulmonary embolism is no longer necessary.
2008 Polytobacco Use Rate at 2.5 Percent in U.S. Adults
FRIDAY, Aug. 6 (HealthDay News) -- In 2008, the rate of polytobacco use (mostly cigarettes in combination with other tobacco products) was 2.5 percent among U.S. adults, with prevalence highest among men, young adults, single adults, low-income households, and those with lower levels of education, according to a report published in the Aug. 6 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
Aerobic Training for Asthma Shows Psychosocial Benefits
THURSDAY, Aug. 5 (HealthDay News) -- In adults with asthma, an aerobic training program may reduce anxiety, depression, and asthma symptoms and improve health-related quality of life, according to research published in the August issue of Chest.
Diabetes Linked to Reduced Pulmonary Function
THURSDAY, Aug. 5 (HealthDay News) -- Diabetes, without the presence of overt pulmonary disease, is linked to a small but significant degree of pulmonary function impairment in a restrictive pattern, according to research published in the August issue of Chest.
Approach in Different Settings Leads to Similar OSA Outcomes
THURSDAY, Aug. 5 (HealthDay News) -- Sleep-laboratory diagnosis and initiation of therapy for obstructive sleep apnea (OSA) doesn't lead to better four-week outcomes compared to home-based diagnosis and treatment, according to research published in the August issue of Chest.
Researchers Test Three Agents for Hereditary Angioedema
WEDNESDAY, Aug. 4 (HealthDay News) -- Researchers have found C1 inhibitor concentrate, ecallantide (a recombinant plasma kallikrein inhibitor), and icatibant (a selective bradykinin B2 receptor antagonist) effective in the management and relief of symptoms of hereditary angioedema, according to three studies published in the Aug. 5 issue of the New England Journal of Medicine.
Full Text - C1 Inhibitor (subscription or payment may be required)
Full Text - Ecallantide (subscription or payment may be required)
Full Text - Icatibant (subscription or payment may be required)
Editorial (subscription or payment may be required)
Industry-Funded Clinical Trials Yield More Positive Outcomes
TUESDAY, Aug. 3 (HealthDay News) -- Drug clinical trials supported by industry are more likely to produce favorable results than trials supported by government or nonprofit/nonfederal organizations, and they are less likely to be published within two years of the study being completed, according to research published in the Aug. 3 issue of the Annals of Internal Medicine.
Fever Alone Unreliable Indicator of H1N1 Infection
MONDAY, Aug. 2 (HealthDay News) -- Standard diagnostic criteria used for the diagnosis of 2009 H1N1 influenza infection, based on the presence of fever, may fail to identify patients with the disease, and respiratory symptoms may be more reliable indicators, according to research published in the August issue of the American Journal of Infection Control.
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