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Category: Cardiology | Monthly Briefing

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September 2010 Briefing - Cardiology

Last Updated: October 01, 2010.

 

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Here are what the editors at HealthDay consider to be the most important developments in Cardiology for September 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

C-Reactive Protein Levels Vary by Ethnicity

TUESDAY, Sept. 28 (HealthDay News) -- Mean C-reactive protein (CRP) concentrations vary for different ethnic populations, which may affect assessment of cardiovascular risk and eligibility for statin treatment, according to a meta-analysis published online Sept. 28 in Circulation: Cardiovascular Genetics.

Abstract
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Look AHEAD Results Favor Intensive Lifestyle Intervention

TUESDAY, Sept. 28 (HealthDay News) -- Intensive lifestyle intervention (ILI) for patients with type 2 diabetes can result in sustained improvements in cardiovascular risk factors and in fitness, according to a report published in the Sept. 27 issue of the Archives of Internal Medicine.

Abstract
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Anti-Apo A-1 Marker for Cardiac Events in RA Patients

TUESDAY, Sept. 28 (HealthDay News) -- An IgG antibody called anti-apolipoprotein A-1 (anti-Apo A-1) is predictive of major cardiovascular events in patients with rheumatoid arthritis (RA), according to research published in the September issue of Arthritis & Rheumatism.

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Pine Bark Extract Doesn't Improve Cardio Risk Profile

TUESDAY, Sept. 28 (HealthDay News) -- Among subjects with elevated cardiovascular disease (CVD) risk, pine bark extract, a dietary supplement rich in antioxidants, does not significantly improve CVD risk profiles, according to a study in the Sept. 27 issue of the Archives of Internal Medicine.

Abstract
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BNP Level Up in Many Pregnant Women With Heart Disease

TUESDAY, Sept. 28 (HealthDay News) -- Measuring B-type natriuretic peptide (BNP) levels of women during pregnancy may be useful in identifying those at risk for adverse cardiac events, according to research published in the Oct. 5 issue of the Journal of the American College of Cardiology.

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Terlipressin Linked to Sodium Reduction in Bleeding Patients

TUESDAY, Sept. 28 (HealthDay News) -- Patients with severe portal-hypertensive bleeding who are treated with terlipressin commonly have an acute reduction in serum sodium concentration that is associated with neurological complications and is usually reversible after the treatment is ended, according to research published in the October issue of Hepatology.

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Software Download Avoids Implantable Defibrillator Shock

MONDAY, Sept. 27 (HealthDay News) -- Software that can be downloaded during a routine doctor visit without surgery reduces the risk of inappropriate shocks for patients with implantable cardioverter-defibrillators (ICDs), according to a study published online Sept. 27 in Circulation.

Abstract
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Mortality Risk Predictor for Stroke Patients Devised

MONDAY, Sept. 27 (HealthDay News) -- Using Get With The Guidelines-Stroke (GWTG-Stroke) data, researchers have developed a new mortality risk predictor for patients hospitalized with ischemic stroke, according to research published online Sept. 27 in Circulation.

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Cardiac MR Imaging Reveals Changes in Elite Triathletes

MONDAY, Sept. 27 (HealthDay News) -- Cardiac magnetic resonance imaging (MRI) of elite triathletes suggests eccentric and concentric remodeling with regulative enlargement of ventricular and atrial chambers, according to research published in the October issue of Radiology.

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Carotid Endarterectomy Tied to Long-Term Stroke Reduction

FRIDAY, Sept. 24 (HealthDay News) -- Carotid endarterectomy (CEA) performed in asymptomatic patients under 75 years of age appears to reduce 10-year stroke risks, with half this reduction in disabling or fatal strokes, according to a study published in the Sept. 25 issue of The Lancet.

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CDC Analyzes Neonatal Heart Defect Deaths by Race

FRIDAY, Sept. 24 (HealthDay News) -- The racial and gestational age differences in neonatal congenital heart defect deaths are significant, but the causes of these differences are not clear, according to a report published in the Sept. 24 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Cytotoxic Testicular Cancer Treatment May Raise CVD Risk

FRIDAY, Sept. 24 (HealthDay News) -- Men who receive chemotherapy, radiotherapy (RT), or a combination of the two as treatment for testicular cancer (TC) may be at increased long-term risk for cardiovascular disease (CVD), according to research published online Sept. 20 in the Journal of Clinical Oncology.

Abstract
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Coronary Artery Calcium Linked to Heart Wall Motion Issues

THURSDAY, Sept. 23 (HealthDay News) -- Subclinical atherosclerosis, as measured by coronary artery calcium (CAC), is associated with a higher chance of later regional wall motion abnormalities (RWMAs), according to research published in the October issue of Radiology.

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Higher Volume Linked to Fewer Adverse Events With ICDs

THURSDAY, Sept. 23 (HealthDay News) -- Patients who receive an implantable cardioverter-defibrillator (ICD) at a high-volume hospital rather than a low-volume hospital are less likely to have an adverse event related to the procedure, according to research published in the Sept. 28 issue of the Journal of the American College of Cardiology.

Abstract
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Venous Thromboembolism Seen After 1% of Hip Replacements

THURSDAY, Sept. 23 (HealthDay News) -- Venous thromboembolism following total hip replacement occurs in roughly 1 percent of patients who receive pharmacological thromboprophylaxis, and factors associated with increased risk of venous thromboembolism include osteoarthritis, a history of cardiovascular disease, and previous thromboembolism, according to research published in the Sept. 15 issue of the Journal of Bone & Joint Surgery.

Abstract
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Fondaparinux Effective in Superficial-Vein Thrombosis

WEDNESDAY, Sept. 22 (HealthDay News) -- Fondaparinux appears to be safe and effective for reducing symptomatic superficial-vein thrombosis of the legs and may reduce the risk of that condition progressing to deep-vein thrombosis or pulmonary embolism, according to the results of a large randomized trial published in the Sept. 23 issue of the New England Journal of Medicine.

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Transcatheter Aortic-Valve Implant Viable Option for Some

WEDNESDAY, Sept. 22 (HealthDay News) -- Transcatheter aortic-valve implantation (TAVI) appears to be more effective in reducing the rates of death, repeat hospitalization, and cardiac symptoms than standard therapy in patients with aortic stenosis who are not suitable candidates for surgery despite a higher risk of major stroke and vascular complications, according to a study published online Sept. 22 in the New England Journal of Medicine.

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Ablation Therapy Effective for Atrial Fibrillation in Young

WEDNESDAY, Sept. 22 (HealthDay News) -- Atrial fibrillation (AF) patients under the age of 45 who undergo ablative therapy experience fewer major complications and similar efficacy as older patients, and have a higher chance of remaining AF free without the use of antiarrhythmic drugs (AADs), according to research published online Sept. 21 in Circulation: Arrhythmia and Electrophysiology.

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Antipsychotics Linked to Risk of Venous Thromboembolism

WEDNESDAY, Sept. 22 (HealthDay News) -- People taking antipsychotic medication may be at risk for venous thromboembolism, and the risk varies by drug type and potency, according to research published Sept. 21 in BMJ.

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Self-Management Counseling May Not Aid in Heart Failure

TUESDAY, Sept. 21 (HealthDay News) -- Self-management counseling in addition to an enhanced educational intervention for patients with mild to moderate heart failure does not appear to have any benefit over the educational intervention alone, according to research published in the Sept. 22/29 issue of the Journal of the American Medical Association.

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Low-Dose Heparin May Not Be Better Than Standard-Dose

TUESDAY, Sept. 21 (HealthDay News) -- In high-risk patients with non-ST-segment elevation acute coronary syndromes initially treated with fondaparinux, low-dose heparin does not appear to reduce major peri-percutaneous coronary intervention (PCI) bleeding or vascular access site complications, according to research published in the Sept. 22/29 issue of the Journal of the American Medical Association.

Abstract
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Metabolic Syndrome Tied to Doubled Risk of CV Outcomes

TUESDAY, Sept. 21 (HealthDay News) -- Individuals with metabolic syndrome have a doubled risk of cardiovascular outcomes and a 58 percent higher risk of all-cause mortality, according to a meta-analysis published in the Sept. 28 issue of the Journal of the American College of Cardiology.

Abstract
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Thigh-Length Stockings Help Avert Thromboses After Stroke

TUESDAY, Sept. 21 (HealthDay News) -- In hospitalized stroke patients, proximal deep venous thrombosis (DVT) is less common in those who wear prophylactic thigh-length stockings than in those who wear below-knee stockings, according to a study published online Sept. 20 in the Annals of Internal Medicine.

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Occupational, Leisure Activity Tied to Heart Failure Risk

TUESDAY, Sept. 21 (HealthDay News) -- Engaging in moderate or high levels of occupational or leisure-time physical activity may reduce the risk of heart failure among both men and women, according to a study in the Sept. 28 issue of the Journal of the American College of Cardiology.

Abstract
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Elevated Post-Op Glucose Ups Risk of Surgical Site Infection

TUESDAY, Sept. 21 (HealthDay News) -- Postoperative hyperglycemia is an important risk factor for surgical site infection (SSI) in general surgical procedures, but only operative time and diabetes are associated with SSI after vascular procedures, according to research published in the September issue of the Archives of Surgery.

Abstract
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Adding Clopidogrel to PPIs Does Not Increase Cardio Risk

TUESDAY, Sept. 21 (HealthDay News) -- Proton-pump inhibitors (PPIs) are associated with an increased risk of adverse cardiovascular outcomes after discharge in patients hospitalized for myocardial infarction (MI); however, concomitant use of clopidogrel is not associated with any additional cardiovascular risk, according to a study in the Sept. 21 issue of the Annals of Internal Medicine.

Abstract
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Influenza Vaccine Tied to Reduced Heart Attack Rate

TUESDAY, Sept. 21 (HealthDay News) -- Influenza -- but not pneumococcal -- vaccination may reduce the rate of first acute myocardial infarction, according to a study published online Sept. 20 in CMAJ, the journal of the Canadian Medical Association.

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Type of RNA Molecule Less Abundant in Diabetes

MONDAY, Sept. 20 (HealthDay News) -- People with diabetes mellitus appear to have lower blood levels of microRNAs (miRNAs) compared with healthy individuals, and these lower levels are detectable before manifestation of the disease, according to research published in the Sept. 17 issue of Circulation Research.

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Diabetes, Elevated A1C Increase Heart Failure Risk

MONDAY, Sept. 20 (HealthDay News) -- For patients with stable coronary artery disease (CAD), having an elevated A1C level increases the risk of heart failure, as does diabetes, independent of other risk factors, according to research published in the September issue of Diabetes Care.

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Three Cardiac Resynchronization Defibrillators Approved for New Use

FRIDAY, Sept. 17 (HealthDay News) -- The U.S. Food and Drug Administration has approved a new use for three cardiac resychronization therapy defibrillators (CRT-D) to treat people with left bundle branch block who also have mild cases of heart failure or heart failure with no symptoms.

this approval

Depression, CHD Add Up to Higher Risk of Mortality

FRIDAY, Sept. 17 (HealthDay News) -- Individuals with depressive symptoms and coronary heart disease (CHD) have a particularly high risk of all-cause and cardiovascular death compared to individuals with one of these problems or neither, according to research published online Sept. 15 in Heart.

Abstract
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Stenting in Aortic Coarctation at Least Equals Other Methods

FRIDAY, Sept. 17 (HealthDay News) -- The short- and long-term outcomes of stent implantation for aortic coarctation appear comparable or superior to those of other approaches, according to research published in the October issue of Catheterization & Cardiovascular Interventions.

Abstract
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Lung Function Tied to Diabetes and Heart Disease Risk

THURSDAY, Sept. 16 (HealthDay News) -- Restrictive impaired lung function among men without a history of cardiovascular disease or diabetes appears to be associated with fatal coronary heart disease (CHD) and incident type 2 diabetes, according to a study published in the September issue of Diabetes Care.

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Most in Asian Malay Group With Diabetes Have Poor BP Control

THURSDAY, Sept. 16 (HealthDay News) -- More than 75 percent of an Asian Malay population with diabetes has poor glycemic and blood pressure (BP) control, according to a study published in the September issue of the Archives of Ophthalmology.

Abstract
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High Cortisol Levels Associated With Cardiovascular Death

THURSDAY, Sept. 16 (HealthDay News) -- High levels of cortisol strongly predict cardiovascular death, even in people without pre-existing cardiovascular disease (CVD), according to research published online Aug. 25 in the Journal of Clinical Endocrinology & Metabolism.

Abstract
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Anemia Therapy in Diabetes Patients With CKD Carries Risk

THURSDAY, Sept. 16 (HealthDay News) -- Patients with chronic kidney disease (CKD), type 2 diabetes, and anemia treated with an erythropoiesis-stimulating agent (ESA) who have a poor initial response are at higher risk for cardiovascular events and death than better-responding patients, according to a study in the Sept. 16 issue of the New England Journal of Medicine.

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Switching to Prasugrel May Help ACS Patients

WEDNESDAY, Sept. 15 (HealthDay News) -- Patients who take maintenance clopidogrel after an acute coronary syndrome (ACS) event appear to have a further reduction in platelet function if they switch to prasugrel, according to a study published in the Sept. 21 issue of the Journal of the American College of Cardiology.

Abstract
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Hyperglycemia Linked to Poor Outcomes in Ischemic Stroke

WEDNESDAY, Sept. 15 (HealthDay News) -- Among patients who suffer ischemic stroke, hyperglycemia at admission may increase the risks for poor outcomes after thrombolysis, according to a study in the September issue of the Archives of Neurology.

Abstract
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Distressed Personality Tied to Cardiovascular Outcomes

WEDNESDAY, Sept. 15 (HealthDay News) -- Type D (distressed) personality, a general propensity to distress defined by high "negative affectivity" and "social inhibition" scores, has adverse effects on cardiovascular outcomes, according to research published in the September issue of Circulation: Cardiovascular Quality and Outcomes.

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Depression, Burnout Have Dire Impact on Medical Training

TUESDAY, Sept. 14 (HealthDay News) -- Depressed medical students are more likely to endorse depression stigma attitudes than nondepressed students, and those with burnout are more likely to engage in unprofessional conduct and less likely to hold altruistic views of physicians' social responsibilities than those without burnout, according to two articles published in the Sept. 15 issue of the Journal of the American Medical Association.

Abstract - Schwenk
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Abstract - Dyrbye
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Sacrifice Makes Industry Gifts Seem More Acceptable

TUESDAY, Sept. 14 (HealthDay News) -- Residents who are reminded of the sacrifices they made to attain their medical education tend to rate the acceptability of industry-sponsored gifts higher than those who are not reminded, according to research published in the Sept. 15 issue of the Journal of the American Medical Association.

Abstract
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Long-Term NSAID Use Ups Risk of Atrial Fibrillation

TUESDAY, Sept. 14 (HealthDay News) -- Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with an increased risk of chronic atrial fibrillation (AF), according to research published in the Sept. 13 issue of the Archives of Internal Medicine. According to a second study published in the same issue, using combinations of anticoagulants -- as opposed to warfarin alone -- significantly raises the risk of bleeding events in patients with AF.

Abstract - De Caterina
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Abstract - Hansen
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Cilostazol As Good As Aspirin for Stroke Prevention

TUESDAY, Sept. 14 (HealthDay News) -- The antiplatelet drug cilostazol is non-inferior, and possibly superior, to aspirin for secondary stroke prevention, and is associated with fewer hemorrhagic events, according to research from the second Cilostazol Stroke Prevention Study (CSPS 2) published online Sept. 11 in The Lancet Neurology.

Abstract
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Visceral Fat Associated With Noncalcified Coronary Plaques

TUESDAY, Sept. 14 (HealthDay News) -- Visceral adipose tissue (VAT) appears to be significantly associated with the development of noncalcified coronary plaques (NCPs) and vulnerable characteristics identified by computed tomography angiography (CTA), which could explain the cardiovascular risk in people with bigger waistlines, according to research published in the September issue of the Journal of the American College of Cardiology: Cardiovascular Imaging.

Abstract
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Women Adapt Differently to Myocardial Pressure Overload

TUESDAY, Sept. 14 (HealthDay News) -- A woman's physiology may result in faster regression of left ventricular (LV) hypertrophy after aortic valve replacement, according to research published in a supplement to the Sept. 14 issue of Circulation.

Abstract
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Re-Consent Important Before Secondary Use of Genetic Data

MONDAY, Sept. 13 (HealthDay News) -- Most research participants want to be asked for secondary consent -- referred to as re-consent -- before their existing personal genetic data are added to the federal database of Genotypes and Phenotypes (dbGaP), according to research published in the September issue of the Journal of Empirical Research on Human Research Ethics.

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Chest Compression First Equal to Immediate Defibrillation

MONDAY, Sept. 13 (HealthDay News) -- Chest compression prior to defibrillation is as successful as -- but not superior to -- immediate defibrillation in individuals who suffer out-of-hospital cardiac arrest, though it is possible that chest compression first is more beneficial when the response time is prolonged, according to a meta-analysis published online Sept. 9 in BMC Medicine.

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Aspirin Reduces Cardiac Events, Mortality in Kidney Patients

FRIDAY, Sept. 10 (HealthDay News) -- Antiplatelet therapy in hypertensive patients with chronic kidney disease (CKD) significantly reduces cardiovascular events and mortality, outweighing a nonsignificant increase in major bleeding risk, according to research published in the Sept. 14 issue of the Journal of the American College of Cardiology.

Abstract
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Unfit Men With Long Hours Have Higher Cardiac Death Risk

FRIDAY, Sept. 10 (HealthDay News) -- Compared with men who work less than 40 hours per week, men with low physical fitness working more than 45 hours per week are at increased risk of ischemic heart disease (IHD) mortality, but this is not the case for men with intermediate or high fitness levels who work long hours, according to a study published online Sept. 6 in Heart.

Abstract
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Stenting for Carotid Stenosis Unsafe for Older Adults

FRIDAY, Sept. 10 (HealthDay News) -- Stenting for treatment of carotid stenosis should be avoided in patients 70 years of age or older, but the approach appears to be as safe as endarterectomy in patients younger than 70, according to a meta-analysis published online Sept. 10 in The Lancet.

Abstract
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High-Quality Primary Care Tied to Improved Health Outcomes

FRIDAY, Sept. 10 (HealthDay News) -- Higher-quality coronary heart disease (CHD) care among general practices in the United Kingdom is associated with lower CHD admissions and mortality rates, with the association strongest among practices serving populations with high levels of deprivation, according to a study in the October issue of the Journal of Epidemiology and Community Health.

Abstract
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Oxidative Biomarkers Useful in Estimating Coronary Risks

THURSDAY, Sept. 9 (HealthDay News) -- A baseline panel of oxidative biomarkers and lipoprotein(a) (Lp[a]) in healthy subjects can be combined with traditional risk factors to better estimate coronary artery disease (CAD) risk, according to a study in the Sept. 14 issue of the Journal of the American College of Cardiology.

Abstract
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Findings Support Whole-Heart MRA for Detecting CAD

THURSDAY, Sept. 9 (HealthDay News) -- Non-contrast enhanced whole-heart coronary magnetic resonance angiography (MRA) at 1.5-T has high sensitivity and moderate specificity for detecting significant coronary artery disease (CAD), with a negative predictive value suggesting that it can rule out CAD, according to research published in the Sept. 14 issue of the Journal of the American College of Cardiology.

Abstract
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Annual Medical Liability Costs Surpass $50 Billion

THURSDAY, Sept. 9 (HealthDay News) -- The annual costs of the medical liability system in the United States total more than $50 billion, which accounts for a relatively small but non-trivial portion of total health care spending, according to an article in the September issue of Health Affairs.

Abstract
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More Stomach, Fewer Chest Complaints Seen in ERs

WEDNESDAY, Sept. 8 (HealthDay News) -- The percentage of non-injury visits to the emergency department for stomach pain has increased, while the percentage of chest pain-related visits has decreased, and use of advanced imaging for both has increased substantially, according to a September data brief released by the National Center for Health Statistics (NCHS).

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ICD Electrograms Can Identify Ventricular Tachycardia Events

WEDNESDAY, Sept. 8 (HealthDay News) -- Electrograms (EGMs) produced by implantable cardioverter-defibrillators (ICDs) can be used to distinguish episodes of post-infarction clinical ventricular tachycardia (VT) from other types of VT when 12-lead electrocardiograms (ECGs) of the episodes are not available, according to a study in the Sept. 14 issue of the Journal of the American College of Cardiology.

Abstract
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U.S. Adult Smoking Rate Stabilizes After Decline

WEDNESDAY, Sept. 8 (HealthDay News) -- The proportion of U.S. adult smokers has remained stable since a decline between 2000 and 2005, with rates of secondhand smoke exposure among nonsmokers remaining high despite recent decreases, according to two early-release reports published Sept. 7 in the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Novel Risk Score Predicts Long-Term Mortality After PCI

WEDNESDAY, Sept. 8 (HealthDay News) -- A risk scoring model that includes post-procedural complications predicts long-term mortality in patients undergoing percutaneous coronary intervention (PCI), according to research published in the Sept. 1 issue of the American Journal of Cardiology.

Abstract
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Education Level Not Predictive of CV Risk in All Countries

WEDNESDAY, Sept. 8 (HealthDay News) -- The protective effect of higher attained educational level (AEL) on cardiovascular outcomes reported for high-income countries (HICs) may not hold true for low- and middle-income countries (LMICs), especially for women, according to a study published online Sept. 7 in Circulation.

Abstract
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Social Factors Influence Physiology After Cardiac Arrest

WEDNESDAY, Sept. 8 (HealthDay News) -- In a mouse model of cardiac arrest/cardiopulmonary resuscitation (CA/CPR), mice that had been socially isolated had a worsened physiologic state post-resuscitation than non-isolated mice, according to a study published online Aug. 30 in the Proceedings of the National Academy of Sciences.

Abstract
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Celiprolol Effective in Vascular Ehlers-Danlos Syndrome

TUESDAY, Sept. 7 (HealthDay News) -- Individuals with vascular Ehlers-Danlos syndrome may benefit from celiprolol treatment, as the drug appears to be effective in preventing arterial dissections and ruptures, according to a study published online Sept. 7 in The Lancet.

Abstract
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Discrepancies Seen Between Docs, Patients on PCI Beliefs

TUESDAY, Sept. 7 (HealthDay News) -- Patients undergoing elective coronary catheterization and possible percutaneous coronary intervention (PCI) are generally much more likely than their physicians to believe the procedure will prevent a heart attack, according to research published in the Sept. 7 issue of the Annals of Internal Medicine.

Abstract
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Meta-Analysis Supports MRA in Peripheral Arterial Disease

TUESDAY, Sept. 7 (HealthDay News) -- Contrast-enhanced magnetic resonance angiography (MRA) appears highly accurate in assessing steno-occlusions in adults with symptoms of peripheral arterial disease (PAD), according to research published in the Sept. 7 issue of the Annals of Internal Medicine.

Abstract
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PFOA, PFOS Appear to Raise Lipid Levels in Children

TUESDAY, Sept. 7 (HealthDay News) -- Increased perfluorooctanoic acid (PFOA) and perfluorooctanesulfonate (PFOS) levels are associated with elevated serum lipid levels in children and adolescents, though the links warrant further evaluation, according to a study in the September issue of the Archives of Pediatrics & Adolescent Medicine.

Abstract
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Bowel Disease Is Risk Factor for Recurrent VTE

FRIDAY, Sept. 3 (HealthDay News) -- Individuals with inflammatory bowel disease (IBD) who have had a venous thromboembolism (VTE) have a higher risk of having a recurrence than those with a prior VTE but no IBD, according to a study in the September issue of Gastroenterology.

Abstract
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QRS Infarct Scoring Is Good Prognostic Indicator

FRIDAY, Sept. 3 (HealthDay News) -- Infarct size estimated by QRS scoring on discharge electrocardiogram is a prognostic indicator in patients with ST-segment elevation myocardial infarction (STEMI) who undergo primary percutaneous coronary intervention (PCI), according to a study published in the Sept. 1 issue of the American Journal of Cardiology.

Abstract
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Ezetimibe/Simvastatin Combo Lowers LDL in Type 2 Diabetes

FRIDAY, Sept. 3 (HealthDay News) -- For patients with type 2 diabetes who are not meeting recommended low-density lipoprotein (LDL) cholesterol goals, adding ezetimibe to simvastatin treatment significantly increases the likelihood of reaching an LDL cholesterol level below 70 mg/dL, according to a study published in the September issue of Diabetes Care.

Abstract
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Healthy Lifestyle May Attenuate Short Telomere Associations

THURSDAY, Sept. 2 (HealthDay News) -- Engaging in a healthy lifestyle might counterbalance the association between coronary artery calcium (CAC) and shorter telomeres in people who have the latter, according to research published in the Sept. 1 issue of the American Journal of Cardiology.

Abstract
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Coronary Collateral Flow Predicts Outcomes in STEMI

THURSDAY, Sept. 2 (HealthDay News) -- The extent of coronary collateral flow in ST-elevation myocardial infarction (STEMI) patients prior to mechanical reperfusion may predict their long-term clinical outcomes, according to research published in the Sept. 1 issue of the American Journal of Cardiology.

Abstract
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Sibutramine May Raise Risks in Those With CVD, Diabetes

WEDNESDAY, Sept. 1 (HealthDay News) -- In overweight or obese subjects with cardiovascular disease (CVD) and diabetes, long-term use of sibutramine is associated with an increased risk of nonfatal myocardial infarction (MI) and nonfatal stroke but not cardiovascular death or any-cause death, according to a study in the Sept. 2 issue of the New England Journal of Medicine.

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Intensive BP Therapy May Not Slow CKD Progression

WEDNESDAY, Sept. 1 (HealthDay News) -- Intensive blood pressure (BP) therapy does not affect hypertensive chronic kidney disease (CKD) progression in most black patients compared to standard BP control, but a potential benefit has been seen for some patients with proteinuria, according to a study in the Sept. 2 issue of the New England Journal of Medicine.

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Fontan Survivors Show Less IART Than Previously Reported

WEDNESDAY, Sept. 1 (HealthDay News) -- The prevalence of intra-atrial re-entrant tachycardia (IART) in a large group of survivors of the Fontan operation is lower than that reported in previous studies, and certain factors appear to be linked to development of this problem, according to research published in the Sept. 7 issue of the Journal of the American College of Cardiology.

Abstract
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Studies Assess Heart Failure With Normal Ejection Fraction

WEDNESDAY, Sept. 1 (HealthDay News) -- Patients with heart failure with normal ejection fraction (HFNEF) have a similar peak exercise pulmonary capillary wedge pressure (PCWP) compared to controls but at a lower workload, and the condition is marked by depressed reserve capacity with a variety of issues related to cardiovascular function, according to two studies published in the Sept. 7 issue of the Journal of the American College of Cardiology.

Abstract - Maeder
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Abstract - Borlaug
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Cardiac Rehab Referral Recommendations Updated

WEDNESDAY, Sept. 1 (HealthDay News) -- The American College of Cardiology Foundation, the American Association of Cardiovascular and Pulmonary Rehabilitation, and the American Heart Association have issued updated performance measures on cardiac rehabilitation and secondary prevention services for patients who have experienced a cardiac event. The new performance measures were published online Aug. 30 in the Journal of the American College of Cardiology.

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