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Category: Internal Medicine | Monthly Briefing

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January 2009 Briefing - Internal Medicine

Last Updated: February 01, 2009.

 

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Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for January 2009. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Number of Low Birth Weight Babies Rises in Massachusetts

FRIDAY, Jan. 30 (HealthDay News) -- The steady rise in the number of low birth weight babies in Massachusetts from 1997 to 2004 can only partially be explained by the increased use of assisted reproductive technology, according to a report published in the Jan. 30 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Anticholinergic Agents Linked to Cognitive Impairment

FRIDAY, Jan. 30 (HealthDay News) -- Cumulative long-term use of anticholinergic medications can lead to cognitive impairment, including poor memory and executive function, according to study findings published in the December issue of the Journal of the American Geriatrics Society.

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Immune Memory Attributed to Natural Killer Cells

FRIDAY, Jan. 30 (HealthDay News) -- The natural killer cells of the innate immune system "remember" prior activation, allowing them to become more easily reactivated, according to research published online Jan. 30 in the Early Edition of the Proceedings of the National Academy of Sciences.

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Data Point Out Why Certain Mutation in GI Tumor Occurs

FRIDAY, Jan. 30 (HealthDay News) -- New evidence may explain why just isoleucine is naturally selected as a resistance mutant at position 670 of the tyrosine kinase KIT in patients with gastrointestinal stromal tumors (GIST) treated with imatinib, according to research published in the Feb. 4 issue of the Journal of the National Cancer Institute.

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Human Papillomavirus Load Linked to Cervical Cytology

FRIDAY, Jan. 30 (HealthDay News) -- Levels of human papillomavirus-18 (HPV-18) DNA in cervical tissue are only associated with the severity of cervical cytology in women who do not go on to develop a precursor to cervical cancer, according to a report published in the Feb. 4 issue of the Journal of the National Cancer Institute.

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Treatment Regimens Equally Effective for Larynx Cancer

FRIDAY, Jan. 30 (HealthDay News) -- Sequential and alternating chemotherapy and radiation are equally effective for survival and larynx preservation in patients with larynx cancer, according to an article published in the Feb. 4 issue of the Journal of the National Cancer Institute.

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Americans Face Soaring Health Insurance Premiums

FRIDAY, Jan. 30 (HealthDay News) -- Health insurance premiums in America will double by 2016 unless there are major health care reforms, according to a report titled Health Care in Crisis: How Special Interests Could Double Health Costs and How We Can Stop It, published Jan. 28 by the Public Interest Research Group.

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Mammography Benefits High-Risk Women in Late 30s

FRIDAY, Jan. 30 (HealthDay News) -- For women carrying mutations in the BRCA gene, who are advised to begin mammography screening at as early as 25 to 30 years of age, the reduction in breast cancer mortality outweighs the risk of radiation-induced cancer mortality in women screened annually at 35 to 39 years of age but maybe not younger age groups, according to the results of a study published in the Feb. 4 issue of the Journal of the National Cancer Institute.

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Biomarker Predicts Chronic Kidney Disease Progression

FRIDAY, Jan. 30 (HealthDay News) -- A marker of acute kidney injury is a strong and independent predictor of disease progression in patients with chronic kidney disease, according to research published online Jan. 28 in the Clinical Journal of the American Society of Nephrology.

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Cruciferous Compound Has Effect on Pancreatic Cancer

FRIDAY, Jan. 30 (HealthDay News) -- Benzyl isothiocyanate (BITC), found in broccoli, cabbage and other cruciferous vegetables, can induce apoptosis in human pancreatic cancer cells, according to research published in the Feb. 4 issue of the Journal of the National Cancer Institute.

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In-Flight Medical Emergencies Poorly Documented

FRIDAY, Jan. 30 (HealthDay News) -- Despite the fact that the airline industry is nationally and internationally regulated, there is no standardized documentation of in-flight medical emergencies, according to a report published Jan. 20 in the open access journal Critical Care.

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Reporting of eGFR More Cost-Effective Than Serum Test

THURSDAY, Jan. 29 (HealthDay News) -- Automatic reporting of estimated glomerular filtration rate (eGFR) is more cost-effective than reporting serum creatinine alone in preventing deaths due to chronic kidney disease, but is also associated with a high false-positive rate, according to a report published online Jan. 28 in the Clinical Journal of the American Society of Nephrology.

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FX06 Cuts Percutaneous Coronary Intervention Injury

THURSDAY, Jan. 29 (HealthDay News) -- In patients undergoing percutaneous coronary intervention to treat acute ST-segment elevation myocardial infarction (STEMI), using intravenous FX06, a fibrin-derived naturally occurring peptide, significantly reduces the necrotic core zone, but does not change scar size or troponin I levels, according to study findings published online Jan. 28 in the Journal of the American College of Cardiology.

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Transcription Factors Explain Yeast Differences

THURSDAY, Jan. 29 (HealthDay News) -- A small number of nucleotide changes within transcription factors explains the difference in sporulation efficiency in different strains of Saccharomyces cerevisiae yeast, a finding that may point to a prominent source of phenotypic differences within species, according to research published in the Jan. 23 issue of Science.

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Estrogen Protects Against Effects of High-Fat Diet

THURSDAY, Jan. 29 (HealthDay News) -- Modulation of the estrogen receptor α (ERα) pathway may protect against insulin resistance and glucose intolerance, suggesting it is an effective target for high-fat diet-induced type 2 diabetes, according to the results of a study in mice published online Jan. 22 in Endocrinology.

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Effects of Cardiovascular Drug Torcetrapib Explored

THURSDAY, Jan. 29 (HealthDay News) -- Torcetrapib, a cardiovascular drug that failed the phase 3 trial ILLUMINATE because of increased mortality, has other molecular targets in addition to cholesteryl ester transfer protein (CETP), according to research published online Jan. 22 in Endocrinology.

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Measles Virus May Lead to New Prostate Cancer Treatment

THURSDAY, Jan. 29 (HealthDay News) -- A measles virus strain engineered to express the human carcinoembryonic antigen shows promise in the treatment of prostate cancer, according to research published in the January issue of The Prostate.

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Arterial Stiffness Predicts Hypertension Drug Response

THURSDAY, Jan. 29 (HealthDay News) -- Patients with hypertension and high levels of arterial stiffness are less likely to respond to antihypertensive drugs, researchers report in the Feb. 3 issue of the Journal of the American College of Cardiology.

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Newer Antidepressants Not All the Same

THURSDAY, Jan. 29 (HealthDay News) -- There are significant differences in terms of efficacy and acceptability between 12 new-generation antidepressants, according to an article published online Jan. 29 in The Lancet.

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Bisphenol A Levels Do Not Decrease with Fasting

THURSDAY, Jan. 29 (HealthDay News) -- Bisphenol A, an industrial chemical used in the manufacture of polycarbonate plastics, epoxy resins and polyvinyl chloride plastic, may accumulate in body tissue or be ingested via substantial non-food sources, according to study findings published online Jan. 28 in Environmental Health Perspectives.

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Intravenous Iron Replacement Benefits Dialysis Patients

THURSDAY, Jan. 29 (HealthDay News) -- Ferumoxytol -- a unique intravenous iron product -- may be more effective than oral iron in treating hemodialysis patients, according to a report published online Jan. 28 in the Clinical Journal of the American Society of Nephrology.

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Weight Loss Reduces Urinary Incontinence in Obese Women

WEDNESDAY, Jan. 28 (HealthDay News) -- In overweight and obese women with urinary incontinence, a six-month weight-loss program significantly reduces the frequency of self-reported incontinence episodes, researchers report in the Jan. 29 issue of the New England Journal of Medicine.

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Long-Term Outcomes Favorable in Kidney Donors

WEDNESDAY, Jan. 28 (HealthDay News) -- Kidney donors are likely to enjoy excellent long-term health outcomes, with rates of survival, albuminuria and hypertension similar to those of non-donors, a preserved glomerular filtration rate, and no increased risk of end-stage renal disease, according to study findings published in the Jan. 29 issue of the New England Journal of Medicine.

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Clopidogrel/Proton Pump Inhibitor Combo Questioned

WEDNESDAY, Jan. 28 (HealthDay News) -- Heart attack patients who take both clopidogrel and a proton pump inhibitor other than pantoprazole have an increased risk of reinfarction and may lose the beneficial effects of clopidogrel, according to research published online Jan. 28 in CMAJ, the Canadian Medical Association Journal.

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Glucose Control Important for Acute Coronary Syndrome

WEDNESDAY, Jan. 28 (HealthDay News) -- Cardiologists should be aware of the link between admission hyperglycemia and increased mortality in patients with acute coronary syndrome, according to an article published Feb. 3 in a supplement to the Journal of the American College of Cardiology devoted to glucose issues.

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Rapidly Changing Moles Associated with 'Sun Tan Jab'

WEDNESDAY, Jan. 28 (HealthDay News) -- An untested, injectable drug that is sold on the Internet for its tanning properties is associated with rapidly changing moles, according to an article published online Jan. 27 in BMJ.

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Longer Antibiotic Regimen Superior in Pregnant Women

WEDNESDAY, Jan. 28 (HealthDay News) -- A one-day regimen of the antibiotic nitrofurantoin is markedly less effective than a seven-day regimen to treat asymptomatic bacteriuria in pregnant women, according to research published in the February issue of Obstetrics & Gynecology.

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Early Blood Transfusion Increases Respiratory Risk

WEDNESDAY, Jan. 28 (HealthDay News) -- Early transfusion of packed red blood cells, particularly in large amounts, increases the risk of developing acute respiratory distress syndrome (ARDS) in trauma patients, researchers report in the February issue of Anesthesiology.

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Keeping Ovaries Safe in Some Endometrial Cancer Patients

WEDNESDAY, Jan. 28 (HealthDay News) -- Premenopausal women with early-stage endometrial cancer do not have higher odds of five-year survival if they undergo oophorectomy in addition to hysterectomy, according to study findings published online Jan. 26 in the Journal of Clinical Oncology.

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Faster Response Linked to Improved Cardiac Survival

WEDNESDAY, Jan. 28 (HealthDay News) -- During a recent period, improvements in the "chain of survival" were linked to increased survival following out-of-hospital cardiac arrests in a region of Japan, according to research published online Jan. 26 in Circulation: Journal of the American Heart Association.

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British Breast Screening Leaflet Lacks Information

WEDNESDAY, Jan. 28 (HealthDay News) -- The U.K. breast cancer screening information leaflet, "Breast Screening: the Facts," downplays the risks of screening to the extent that it cannot be relied upon to help a patient make a genuinely informed decision, according to an article published online Jan. 27 in BMJ.

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Chronic Hyperglycemia Linked to Cognitive Dysfunction

WEDNESDAY, Jan. 28 (HealthDay News) -- In patients with type 2 diabetes, higher A1C levels are associated with lower scores on cognitive tests, researchers report in the February issue of Diabetes Care.

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Acupuncture Offers Only Minimal Pain Relief

WEDNESDAY, Jan. 28 (HealthDay News) -- Acupuncture offers some pain relief but at a level below clinical significance, according to a report published online Jan. 28 in BMJ.

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Laws Limit Medicare's Ability to Control Cancer Drug Costs

TUESDAY, Jan. 27 (HealthDay News) -- A unique regulatory and legislative framework prevents Medicare from controlling the quickly escalating costs of cancer drugs, as it does with other drugs and medical goods, according to a report published online Jan. 27 in the New England Journal of Medicine.

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BNP Levels Not a Superior Guide for Heart Failure Therapy

TUESDAY, Jan. 27 (HealthDay News) -- Using N-terminal brain natriuretic peptide (BNP) levels to guide heart failure therapy does not improve overall clinical outcomes or patient quality of life compared to using symptoms to guide treatment, according to a report published in the Jan. 28 issue of the Journal of the American Medical Association.

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Secondhand Smoke Leads to Erectile Dysfunction in Mice

TUESDAY, Jan. 27 (HealthDay News) -- Secondhand smoke reduces erectile function in mice, but the effects can be reversed by treatment with sildenafil, researchers report in the February issue of the Journal of Urology.

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Caloric Restriction Improves Memory in Elderly

TUESDAY, Jan. 27 (HealthDay News) -- Reducing calorie intake by 30 percent improves memory in elderly individuals, according to research published online Jan. 26 in the Proceedings of the National Academy of Sciences.

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Good Survival Post-Cardiac Arrest After Angiography

TUESDAY, Jan. 27 (HealthDay News) -- Patients who are resuscitated after a heart attack have good survival and neurological recovery after undergoing emergent angiography and revascularization, particularly if they are alert post-resuscitation, according to a report in the Feb. 3 issue of the Journal of the American College of Cardiology.

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Counseling Helps Prevent Excessive Pregnancy Weight Gain

TUESDAY, Jan. 27 (HealthDay News) -- Excessive weight gain during pregnancy is effectively prevented with a consistent counseling program focused on diet and lifestyle, according to an article published in the February issue of Obstetrics & Gynecology.

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AHA Supports Omega-6 for Possible Heart Protection

TUESDAY, Jan. 27 (HealthDay News) -- The American Heart Association recommends that at least 5 to 10 percent of individuals' calories should come from omega-6 polyunsaturated fatty acids, according to a science advisory published online Jan. 26 in Circulation: Journal of the American Heart Association.

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Overnight Rostral Fluid Shift Linked to Impaired Sleep

TUESDAY, Jan. 27 (HealthDay News) -- In non-obese men, overnight fluid displacement from the legs to the neck related to prolonged sitting may play a previously unrecognized role in the development of obstructive sleep apnea, according to research published in the February issue of the American Journal of Respiratory and Critical Care Medicine.

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Exercise Can Reduce Insulin Resistance in Obese Elders

TUESDAY, Jan. 27 (HealthDay News) -- Combining resistance and aerobic exercise is the best way to reduce functional limitations and insulin resistance in elderly patients with abdominal obesity, according to study findings published in the Jan. 26 issue of the Archives of Internal Medicine.

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Imaging Detects Cardiac Abnormalities in Endocarditis

TUESDAY, Jan. 27 (HealthDay News) -- Multislice computed tomography (CT) is effective in detecting valvular abnormalities in patients with suspected infective endocarditis compared with transesophageal echocardiography and surgical specimens, researchers report in the Feb. 3 issue of the Journal of the American College of Cardiology.

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Clinical Information Technology Leads to Safer Hospitals

TUESDAY, Jan. 27 (HealthDay News) -- Hospitals that make use of clinical information technology to automate notes, records, order entry and clinical decision support have lower mortality rates, fewer complications and also save money, according to a report published in the Jan. 26 issue of the Archives of Internal Medicine.

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Prolonged Use of Loop Diuretics May Raise Fracture Risk

MONDAY, Jan. 26 (HealthDay News) -- Postmenopausal women who use loop diuretics are at increased risk of fractures, according to a report published in the Jan. 26 issue of the Archives of Internal Medicine.

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Meditation Practice Linked to Less Pain Sensitivity

MONDAY, Jan. 26 (HealthDay News) -- Experience in Zen meditation is associated with reduced pain sensitivity, a finding supporting the value of mindfulness-based meditation, according to research published in the January issue of Psychosomatic Medicine.

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Accidental Infant Bed Deaths Have Quadrupled Since 1984

MONDAY, Jan. 26 (HealthDay News) -- For unknown reasons, the infant mortality rate attributable to accidental suffocation and strangulation in bed has quadrupled since 1984 in the United States, according to study findings published in the February issue of Pediatrics.

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Alcohol-Use Disorders Are Common, But Treatable

MONDAY, Jan. 26 (HealthDay News) -- About one-quarter of individuals with alcohol-use disorders will seek help for their problems, and health care providers should routinely screen for alcohol dependence or abuse, according to a seminar published online Jan. 26 in The Lancet.

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Obstructive Sleep Apnea Linked to Insulin Resistance

MONDAY, Jan. 26 (HealthDay News) -- Obstructive sleep apnea is associated with insulin resistance in obesity and also independently of obesity, which may increase the risk of developing other chronic conditions, according to two studies published in the February issue of the American Journal of Respiratory and Critical Care Medicine.

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Rates of Severe Obstetric Complications on the Rise

MONDAY, Jan. 26 (HealthDay News) -- Severe obstetric complications have occurred at an increasing rate, and many are associated with a mirrored increase in the rate of Caesarean deliveries, according to research published in the February issue of Obstetrics & Gynecology.

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Prostate Cancer May Be Underdiagnosed in Poor Men

MONDAY, Jan. 26 (HealthDay News) -- Although the detection of low-risk prostate cancers has been increasing in the United States due to screening, this is not the case among low-income, disadvantaged men, researchers report in the February issue of the Journal of Urology.

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AHA Reveals Top 10 Heart Disease Research Advances

MONDAY, Jan. 26 (HealthDay News) -- The American Heart Association (AHA) has released its annual top 10 list of advances in research into heart disease and stroke, with a study on the impact of smoke-free legislation on hospitalizations for acute coronary syndrome topping the list.

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Formulas Show Promising GFR Estimation in Children

MONDAY, Jan. 26 (HealthDay News) -- New formulas for estimating glomerular filtration rate (GFR) in children with chronic kidney disease can provide results comparable to the best equations for adults, according to research published online Jan. 21 in the Journal of the American Society of Nephrology.

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Smoking Causes Over 440,000 US Deaths Each Year

MONDAY, Jan. 26 (HealthDay News) -- There were an estimated 443,000 deaths a year from 2000 to 2004 attributable to smoking and exposure to secondhand smoke in the United States, according to a report published in the Jan. 23 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Teenage Obesity Linked to Poor Maternal-Fetal Outcomes

MONDAY, Jan. 26 (HealthDay News) -- Overweight and obesity in teenage mothers is associated with an increased risk for adverse perinatal outcomes, according to research published in the February issue of Obstetrics & Gynecology.

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Impaired Kidney Function Linked to Mortality in Elderly

FRIDAY, Jan. 23 (HealthDay News) -- Impaired kidney function is associated with a higher risk of death and cardiovascular disease in elderly individuals at risk of vascular disease, while statins reduce the risk of death and heart attack in patients with impaired kidney function, according to the results of a study published online Jan. 20 in PLoS Medicine.

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No Evidence Base to Support Smoker-Free Workplace Rule

FRIDAY, Jan. 23 (HealthDay News) -- Smoker-free workplace policies unfairly discriminate against smokers and lack an evidence base to support claims that they reduce smoking, according to an article published online Jan. 23 in Tobacco Control.

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Thalidomide May Be Helpful in Recurrent Prostate Cancer

FRIDAY, Jan. 23 (HealthDay News) -- Thalidomide may help delay prostate specific antigen (PSA) progression in some men with prostate cancer, according to research released online Jan. 23 in advance of publication in the March issue of the Journal of Urology.

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Seat Belt, Air Bag Protect Against Spinal Fracture

FRIDAY, Jan. 23 (HealthDay News) -- Although the occurrence of spinal fractures among drivers and front-seat passengers in motor vehicle crashes has increased despite increases in seat belt and air bag use, their combined use is protective against spinal fractures, according to study findings published in the February issue of the Journal of Neurosurgery: Spine.

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Salmonella Outbreaks Highlight Risk from Live Poultry

FRIDAY, Jan. 23 (HealthDay News) -- Exposure to live poultry caused two separate outbreaks of Salmonella in the United States in 2007, according to a report published in the Jan. 23 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Adjuvant Radiation Shows Benefit After Prostate Surgery

FRIDAY, Jan. 23 (HealthDay News) -- Adjuvant radiotherapy shortly after radical prostatectomy in men with extraprostatic prostate cancer is associated with improved survival, according to research released online Jan. 22 in advance of publication in the March issue of the Journal of Urology.

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Acute Geriatric Units Improve Elderly Care

FRIDAY, Jan. 23 (HealthDay News) -- Elderly patients hospitalized with acute medical disorders are more likely to live at home after discharge if they are treated in acute geriatric wards rather than conventional hospital care, according to research published online Jan. 22 in BMJ.

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Single HIV Variants Found in Heterosexual Transmission

FRIDAY, Jan. 23 (HealthDay News) -- Most individuals who become infected with HIV through their spouse are infected with a single viral variant, according to a report published online Jan. 23 in PLoS Pathogens. The study also found that individuals who become infected with multiple viral variants often have inflammatory genital infections, suggesting that the mucosal barrier is largely responsible for the genetic bottleneck.

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Mortality Not Down in Acute Respiratory Distress Syndrome

FRIDAY, Jan. 23 (HealthDay News) -- Despite some assertions to the contrary, mortality from acute respiratory distress syndrome has not significantly decreased since publication of a consensus definition in 1994, according to a report published in the February issue of the American Journal of Respiratory and Critical Care Medicine.

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New Guidelines Issued for Brain Hemorrhage Management

FRIDAY, Jan. 23 (HealthDay News) -- New recommendations summarize the best available evidence for treatment of patients with aneurysmal subarachnoid hemorrhage and identify areas of future research, according to a statement published online Jan. 22 in Stroke.

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Spousal Violence Increases Odds of Fetal Loss

FRIDAY, Jan. 23 (HealthDay News) -- Women whose husbands are violent toward them are more likely to experience single or recurrent fetal loss, researchers report in the Jan. 24 issue of The Lancet.

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'Haufen' Might Help Diagnose Viral Kidney Disease

FRIDAY, Jan. 23 (HealthDay News) -- Three-dimensional aggregates of polyomavirus in urine -- dubbed Haufen -- may be reliable markers of BK polyomavirus nephropathy (BKN), which occurs in up to 9 percent of renal allografts, according to research published online Jan. 21 in the Journal of the American Society of Nephrology.

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Abuse of Dementia Patients by Carers Is Common

FRIDAY, Jan. 23 (HealthDay News) -- It is common for people with dementia to be abused by family carers, most often with verbal abuse, although frequent and physical abuse seems to be rare, according to the results of a study published online Jan. 22 in BMJ.

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Declaration on Medics' Role in Torture Needs Updating

FRIDAY, Jan. 23 (HealthDay News) -- Despite the fact that the Declaration of Tokyo condemns the participation of medical personnel in torture and inhumane treatment, there are key areas in which the declaration should be strengthened, according to an article published in the Jan. 24 issue of The Lancet.

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Ethical HIV Testing in Poor Countries Needed

THURSDAY, Jan. 22 (HealthDay News) -- Testing a patient's blood without their consent for HIV is important for HIV surveillance, but needs to be carefully implemented in developing countries to ensure that testing is done ethically, according to an article published online Jan. 20 in PLoS Medicine.

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Educational Booklets Don't Affect Neck-Pain Outcomes

THURSDAY, Jan. 22 (HealthDay News) -- In neck-pain patients receiving workers' compensation, the use of educational booklets has no significant effect on improving outcomes, according to study findings published in the Jan. 15 issue of Spine.

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Novel Biomarkers Predict Death, Myocardial Infarction

THURSDAY, Jan. 22 (HealthDay News) -- When patients are admitted to the hospital with ischemic-type chest pain, two novel biomarkers can provide useful prognostic information, according to research published in the Jan. 1 issue of the American Journal of Cardiology.

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Occupational Exposures Increase Nurses' Asthma Risk

THURSDAY, Jan. 22 (HealthDay News) -- Nurses who are exposed to occupational cleaning products and disinfectants may have an increased risk of new-onset asthma, according to a report published online Jan. 22 in Occupational and Environmental Medicine.

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Cholesterol Particle Size Associated with Coronary Risk

THURSDAY, Jan. 22 (HealthDay News) -- There is an association between the risk of coronary artery disease and both size and concentration of high-density lipoprotein, although the former is explained by markers associated with the metabolic syndrome, according to research published in the Jan. 20 issue of the Annals of Internal Medicine.

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Car Crashes Among US Elderly Declined in Past Decade

THURSDAY, Jan. 22 (HealthDay News) -- Fatal crash rates among the elderly have fallen in the past decade in the United States, according to research published in a recent issue of the Annals of Advances in Automotive Medicine. A related study published online Jan. 21 in the Cochrane Database of Systematic Reviews notes that studies examining the effect of vision testing on traffic accidents among elderly individuals do not exist.

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Protein Activity Points to Bacterial Persistence

THURSDAY, Jan. 22 (HealthDay News) -- A greater understanding of the mechanisms that underlie persistence in Escherichia coli may point to therapies that reduce bacterial multi-drug tolerance, according to research published in the Jan. 16 issue of Science.

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Vaginal Herpes Microbicide Protects Against Infection

THURSDAY, Jan. 22 (HealthDay News) -- A vaginal microbicide targeting a herpes simplex virus-2 (HSV-2) gene and a host gene protects mice against infection for a week, researchers report in the Jan. 22 issue of Cell Host & Microbe.

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Peanut Butter Crackers, Dog Snacks Among Recalled Items

THURSDAY, Jan. 22 (HealthDay News) -- The list of recalled products resulting from the recent Salmonella typhimurium outbreak has grown, and officials believe a processing plant in Blakely, Ga., may be the source of the outbreak, according to officials speaking at a teleconference conducted Jan. 21 by the U.S. Food and Drug Administration and the U.S. Centers for Disease Control and Prevention.

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Warfarin-Related Genotyping Not Cost-Effective

THURSDAY, Jan. 22 (HealthDay News) -- Genetic testing prior to initiation of warfarin therapy is only cost-effective in patients who are at high risk for hemorrhage, and is not cost-effective for typical patients with non-valvular atrial fibrillation, according to a report published in the Jan. 20 issue of the Annals of Internal Medicine.

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Less Air Pollution Linked to Higher Life Expectancy

WEDNESDAY, Jan. 21 (HealthDay News) -- Reductions in air pollution over the last few decades in the United States are associated with increases in life expectancy, researchers report in the Jan. 22 issue of the New England Journal of Medicine.

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Supplements Can Contain Excess Iodine

WEDNESDAY, Jan. 21 (HealthDay News) -- Some over-the-counter supplements contain high levels of iodine that may interfere with radioiodine treatment in patients with thyroid cancer, according to a case study published in the Jan. 22 issue of the New England Journal of Medicine.

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Schizophrenics Experience High Rates of Discrimination

WEDNESDAY, Jan. 21 (HealthDay News) -- Patients with schizophrenia experience high rates of both anticipated and experienced discrimination, according to an article published online Jan. 21 in The Lancet.

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Novel Laser Technique to Treat Osteonecrosis of the Jaw

WEDNESDAY, Jan. 21 (HealthDay News) -- Bisphosphonate-induced osteonecrosis of the jaw may be effectively treated by a laser bone ablation technique, according to research published in the January issue of Lasers in Surgery and Medicine.

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Industrial Chemical May Be Human Carcinogen

WEDNESDAY, Jan. 21 (HealthDay News) -- The chemical 2-mercaptobenzothiazole (MBT) -- a vulcanizing agent in the rubber manufacturing industry, corrosion inhibitor in auto radiator and metalworking fluids, and stabilizer in the manufacture of plastics -- may be carcinogenic, according to an article published online Jan. 21 in Occupational and Environmental Medicine.

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Novel Light Imaging Technique Detects Melanoma

WEDNESDAY, Jan. 21 (HealthDay News) -- Multimodal polarized light imaging using tetracycline or methylene blue is an effective strategy to image dysplastic and benign nevi in melanoma, researchers report in the January issue of Lasers in Surgery and Medicine.

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CO2 Laser Effective for Oral Precancerous Lesions

WEDNESDAY, Jan. 21 (HealthDay News) -- Carbon dioxide (CO2) laser surgery is an effective treatment strategy for oral precancerous lesions, resulting in up to a 64 percent disease-free clinical outcome, according to research published in the January issue of Lasers in Surgery and Medicine.

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Blacks Less Likely Than Whites to Have Lung Cancer Surgery

WEDNESDAY, Jan. 21 (HealthDay News) -- Among patients with lung cancer, black patients are less likely than white patients to undergo recommended lung resection, but the disparity in treatment does not appear to have an impact on outcomes, according to research published in the January issue of the Archives of Surgery.

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Many Support Surrogate Consent in Dementia Research

WEDNESDAY, Jan. 21 (HealthDay News) -- Most participants in a sample of older Americans supported allowing families to provide surrogate consent decisions as part of research on dementia, and most would also participate in surrogate-based research, according to the results of a study published in the Jan. 13 issue of Neurology.

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Escitalopram Modestly Improves Anxiety in Elderly

TUESDAY, Jan. 20 (HealthDay News) -- The selective serotonin reuptake inhibitor escitalopram modestly improves anxiety symptoms and role functioning compared with placebo in elderly adults with anxiety disorder, according to study findings published in the Jan. 21 issue of the Journal of the American Medical Association.

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Heart Function Linked to Exercise Capacity

TUESDAY, Jan. 20 (HealthDay News) -- Left ventricular resting diastolic function is strongly associated with exercise capacity, along with age, sex and body mass index, according to a report in the Jan. 21 issue of the Journal of the American Medical Association.

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Genetic Variants Predict Heart Disease in Women

TUESDAY, Jan. 20 (HealthDay News) -- Although genetic variations in chromosome 9p21.3 are associated with incident cardiovascular disease in white women, they do not add to the predictive value of traditional risk factors, high-sensitivity C-reactive protein or a family history of premature heart attack, according to a report published in the Jan. 20 issue of the Annals of Internal Medicine.

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Severity of Myocardial Infarction Has Declined

TUESDAY, Jan. 20 (HealthDay News) -- There was a decline in the severity of myocardial infarction from 1987 to 2002, which could help explain the reduction in mortality due to coronary heart disease, according to the results of a study published online Jan. 19 in Circulation: Journal of the American Heart Association.

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Low Neuroticism Linked to Decreased Dementia

TUESDAY, Jan. 20 (HealthDay News) -- Low neuroticism and high social extraversion is associated with a decreased risk of dementia, although low neuroticism lowers risk even among socially isolated persons, according to an article published in the Jan. 20 issue of Neurology.

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