Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for October 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
BPA Exposure Associated With Poorer Semen Quality
FRIDAY, Oct. 29 (HealthDay News) -- Exposure to bisphenol-A (BPA) -- a component of many consumer products, including plastic containers and liners of food and beverage cans -- may have an adverse effect on semen quality, according to research published online Oct. 29 in Fertility and Sterility.
Associations Found Between ADHD and Adulthood BMI
FRIDAY, Oct. 29 (HealthDay News) -- Adolescents who report symptoms of attention-deficit/hyperactivity disorder (ADHD) may be at risk for obesity in adulthood, according to research published online Oct. 26 in the International Journal of Obesity.
Men With Cancer Have High Hypogonadism Prevalence
FRIDAY, Oct. 29 (HealthDay News) -- Men with cancer have a high prevalence of hypogonadism and a resulting reduction in quality of life (QoL) and sexual function, according to a study published online Oct. 25 in the Journal of Clinical Oncology.
Glucose Levels Veer Widely Leading Into Type 1 Diabetes
THURSDAY, Oct. 28 (HealthDay News) -- As individuals progress to type 1 diabetes, their glucose levels show wide fluctuations and gradually increase overall, though glucose fluctuations are not related to early C-peptide response, according to research published in the October issue of Diabetes.
Imaging IDs Insulin Sensitivity Improvement Factors
THURSDAY, Oct. 28 (HealthDay News) -- Assessing adipose body compartments with magnetic resonance (MR) imaging and spectroscopy, researchers have identified factors predictive of improved insulin sensitivity in patients undergoing a lifestyle intervention program; their findings have been published in the November issue of Radiology.
Air Pollution Associated With Diabetes Prevalence
WEDNESDAY, Oct. 27 (HealthDay News) -- Increasing exposure to fine particulate matter air pollution may be one factor explaining the dramatic rise in diabetes prevalence over the past few decades, according to research published in the October issue of Diabetes Care.
Probe-to-Bone Best Test for Diabetic Foot Osteomyelitis
WEDNESDAY, Oct. 27 (HealthDay News) -- The best and most efficient test for diagnosing chronic osteomyelitis of the foot in patients with diabetes may be the probe-to-bone (PTB) test, according to research published in the October issue of Diabetes Care.
Primary Care Trails Other Specialties in Hourly Wages
TUESDAY, Oct. 26 (HealthDay News) -- Primary care physicians have substantially lower hourly wages than other specialists, and although most physicians find Medicare reimbursement inequitable, they show little consensus on how to reform it, according to two studies published in the Oct. 25 issue of the Archives of Internal Medicine.
U.S. Diabetes Prevalence Expected to Skyrocket
FRIDAY, Oct. 22 (HealthDay News) -- By 2050, as many as one in three U.S. adults are expected to have diabetes if current trends continue, according to a new U.S. Centers for Disease Control and Prevention report published Oct. 22 in Population Health Metrics.
Low Testosterone Linked With CVD-Related Mortality
FRIDAY, Oct. 22 (HealthDay News) -- New research suggests a link between low testosterone levels and increased risk of death in men who have heart disease, according to a report published online Oct. 19 in Heart.
Ankle-Brachial Index Linked to Risk of Cardiovascular Disease
THURSDAY, Oct. 21 (HealthDay News) -- Having a low or high ankle-brachial index (ABI) is associated with an increased risk of cardiovascular disease (CVD), according to research published in the Oct. 26 issue of the Journal of the American College of Cardiology.
FDA to Update Prescribing Labels of GnRH Agonists
THURSDAY, Oct. 21 (HealthDay News) -- The U.S. Food and Drug Administration has notified health care professionals and consumers that the prescribing labels of gonadotropin-releasing hormone (GnRH) agonists will be updated with new safety information.
Vitamin D Levels Lower in Basal Cell Nevus Syndrome
TUESDAY, Oct. 19 (HealthDay News) -- Individuals with basal cell nevus syndrome (BCNS), many of whom routinely protect themselves from the sun due to higher risk of skin cancer, appear to be at increased risk of vitamin D deficiency, according to research published in the October issue of the Archives of Dermatology.
Reciprocal Peer Support Promising for Diabetes Care
TUESDAY, Oct. 19 (HealthDay News) -- Compared to a nurse care management (NCM) system, one-to-one reciprocal peer support (RPS) results in greater improvements in hemoglobin A1c (HbA1c) for patients with diabetes, according to research published in the Oct. 19 issue of the Annals of Internal Medicine.
"Natural" Weight Loss Products Pose Danger
FRIDAY, Oct. 15 (HealthDay News) -- An examination of poisoning cases in Hong Kong linked to over-the-counter (OTC) weight loss products often advertised to contain only "natural" ingredients" revealed the products to be laced with multiple illicit ingredients with toxicities that can cause illness or even death, according to a report published online Oct. 13 in the British Journal of Clinical Pharmacology.
Diabetes Hospitalizations Rise Among Young Adults
THURSDAY, Oct. 14 (HealthDay News) -- Hospitalizations associated with diabetes have significantly increased among young adults, in particular young women, according to a study published online Oct. 12 in the Journal of Women's Health.
ANGPTL3 Mutations Tied to Lipid Disorder
THURSDAY, Oct. 14 (HealthDay News) -- ANGPTL3 mutations appear to be associated with extremely low plasma low-density lipoprotein (LDL) cholesterol levels among individuals with familial combined hypolipidemia, which may represent a new target for the lowering of LDL cholesterol levels, according to a brief report published online Oct. 13 in The New England Journal of Medicine.
Bisphosphonate Users at Possible Risk of Thigh Fracture
WEDNESDAY, Oct. 13 (HealthDay News) -- Bisphosphonates may put users at risk for atypical thigh bone fractures, according to a warning to health care providers and patients issued Oct. 13 by the U.S. Food and Drug Administration; the risk will be reflected in a labeling change and Medication Guide.
IOM: Front-of-Package Nutrition Labels Need New Focus
WEDNESDAY, Oct. 13 (HealthDay News) -- Front-of-package (FOP) nutrition labeling would be most helpful to consumers if it clearly highlighted the information of greatest concern -- calories, saturated fat, trans fat, and sodium -- according to the findings of an Institute of Medicine committee review released Oct. 13.
Peripheral Artery Disease Procedures Recurrent, Costly
WEDNESDAY, Oct. 13 (HealthDay News) -- Peripheral artery disease (PAD) carries a high economic burden, with many asymptomatic patients going on to experience an ischemic event requiring hospitalization and many symptomatic patients requiring one or more revascularizations and other procedures, according to research published online Oct. 12 in Circulation: Cardiovascular Quality and Outcomes.
Genetic Research Focuses on Waist-Hip Ratio, BMI
TUESDAY, Oct. 12 (HealthDay News) -- New findings shed light on how genetics may influence body fat distribution and body mass index, as detailed in two studies published online Oct. 10 in Nature Genetics.
Insulin Resistance Is Potential Marker for Ischemic Stroke
TUESDAY, Oct. 12 (HealthDay News) -- Insulin resistance (IR), as measured by homeostasis model assessment (HOMA), appears to be independently associated with an increased risk of first ischemic stroke (IS) among patients without diabetes, potentially providing clinical practitioners with the ability to identify those at high risk of stroke, according to a study published online Oct. 11 in the Archives of Neurology.
Collaboration Required for Better Testosterone Assays
MONDAY, Oct. 11 (HealthDay News) -- Improving testosterone assays for better measurement of testosterone levels will require a multipronged approach involving all parties concerned with achieving this goal, according to a consensus statement published in the October issue of The Journal of Clinical Endocrinology and Metabolism.
Weight Benefit Seen With Motivational Interviewing
MONDAY, Oct. 11 (HealthDay News) -- During visits with overweight patients, using motivational interviewing techniques while discussing weight may encourage weight loss, according to research published in the October issue of the American Journal of Preventive Medicine.
43% of Orthopedic Patients Have Low Vitamin D Level
MONDAY, Oct. 11 (HealthDay News) -- There is a high prevalence of hypovitaminosis D within the adult orthopedic surgery population, according to research published in the Oct. 6 issue of The Journal of Bone and Joint Surgery.
Physical Activity Program Tied to Significant Weight Loss
MONDAY, Oct. 11 (HealthDay News) -- Physical activity and structured weight loss programs appear to be associated with significant weight loss among overweight and obese individuals, according to two studies published online Oct. 9 in JAMA to coincide with presentation at the 28th Annual Scientific Meeting of the Obesity Society, held Oct. 8-12 in San Diego.
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Obesity Drug Pulled From U.S. Market
FRIDAY, Oct. 8 (HealthDay News) -- Abbott Laboratories, maker of Meridia (sibutramine), agreed to voluntarily withdraw the obesity drug from the market because it might place users at increased risk of heart attack and stroke, according to an Oct. 8 announcement from the U.S. Food and Drug Administration.
Usual Prostate Cancer Therapy Linked to Bone Deterioration
FRIDAY, Oct. 8 (HealthDay News) -- Androgen deprivation therapy (ADT) for prostate cancer is associated with bone deterioration, and a new technology may help identify men at risk for fractures related to this deterioration, according to a study published online Sept. 29 in the Journal of Clinical Endocrinology & Metabolism.
Hypoglycemia Associated With Variety of Adverse Outcomes
WEDNESDAY, Oct. 6 (HealthDay News) -- Severe hypoglycemia is associated with a higher risk of a number of adverse clinical outcomes in type 2 diabetes patients, but the relationship may not be causal, according to research published in the Oct. 7 issue of the New England Journal of Medicine.
Testosterone May Lend Benefit in Women With CHF
TUESDAY, Oct. 5 (HealthDay News) -- In women with advanced chronic heart failure, testosterone supplementation is associated with improved functional capacity, insulin resistance, and muscle strength, according to research published in the Oct. 12 issue of the Journal of the American College of Cardiology.
New Method Could Improve in Vitro Fertilization Outcomes
TUESDAY, Oct. 5 (HealthDay News) -- A noninvasive imaging approach for predicting which embryos will reach the blastocyst phase could be useful in assessing the potential of embryos during assisted reproduction, according to research published online Oct. 3 in Nature Biotechnology.
Successful Fat Loss May Require Adequate Sleep
TUESDAY, Oct. 5 (HealthDay News) -- Overweight dieters who don't get enough sleep may lose less fat and more fat-free body mass while experiencing greater hunger than those who get adequate nightly rest, according to research published in the Oct. 5 issue of the Annals of Internal Medicine.
Doctors' Exercise Linked to Confidence Counseling Patients
FRIDAY, Oct. 1 (HealthDay News) -- Physicians' exercise habits and weight are associated with their confidence in their abilities to counsel patients on exercise and diet, as is the level of training they have received in counseling techniques, according to research published in the fall issue of Preventive Cardiology.
Empowerment Strategy May Be Beneficial for IVF Decision
FRIDAY, Oct. 1 (HealthDay News) -- A strategy to empower couples seeking in vitro fertilization (IVF) to decide how many embryos to transfer could increase the number who use single-embryo transfer, therefore reducing the twin pregnancy rate, according to research published Sept. 30 in BMJ.
Depression, Activity Tied to Work Status After Dialysis
FRIDAY, Oct. 1 (HealthDay News) -- Individuals who remain employed after starting dialysis are less likely to experience possible or probable depression than those who quit working, and higher activity level is associated with a greater likelihood of continued employment, according to a report published online Sept. 30 in the Clinical Journal of the American Society of Nephrology.
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