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Category: Family Medicine | Monthly Briefing

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March 2010 Briefing - Family Practice

Last Updated: April 01, 2010.

 

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Here are what the editors at HealthDay consider to be the most important developments in Family Practice for March 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Disability Course in Elderly Usually Not Predictable

WEDNESDAY, March 31 (HealthDay News) -- In most older people followed at the end of life, the condition leading to death isn't associated with a predictable course of disability, according to research published in the April 1 issue of the New England Journal of Medicine.

Abstract
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Advance Directives Effectively Guide End-of-Life Care

WEDNESDAY, March 31 (HealthDay News) -- Elderly persons with reduced decision-making capacity who have prepared advance directives, such as living wills, are likely to receive the kind of end-of-life care they request, according to research published in the April 1 issue of the New England Journal of Medicine.

Abstract
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Editorial (subscription or payment may be required)

Physicians Weigh Many Factors in Surrogate Decision Making

WEDNESDAY, March 31 (HealthDay News) -- Physicians making medical decisions for patients unable to decide for themselves often include factors other than expressed patient preferences in their decisions, even though most physicians consider those preferences their most important guideline, according to a study in the March issue of the Journal of the American Geriatrics Society.

Abstract
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Research Urged to Help Iraq, Afghanistan War Vets Readjust

WEDNESDAY, March 31 (HealthDay News) -- The U.S. departments of Defense and Veterans Affairs urgently need to conduct research on how to help veterans of the Iraq and Afghanistan wars and their families readjust to post-deployment life and cope with mental health problems, as well as improve the management of traumatic brain injury (TBI), according to Returning Home from Iraq and Afghanistan, a preliminary assessment of veterans' needs by the Institute of Medicine of the National Academies.

Press Release
Online Text of Returning Home from Iraq and Afghanistan

Melanoma Survivors Face High Second Primary Cancer Risk

WEDNESDAY, March 31 (HealthDay News) -- Melanoma survivors have a substantially higher risk of developing subsequent melanoma, as well as a higher risk of developing several other types of cancer, according to research published in the March issue of the Archives of Dermatology.

Abstract
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Asclera Approved to Treat Varicose Veins

WEDNESDAY, March 31 (HealthDay News) -- Polidocanol (Asclera) has been approved by the U.S. Food and Drug Administration to treat small varicose veins, the agency said in a news release.

National Library of Medicine

Pediatric Endocrinologists Vary Widely in Diabetes Practices

WEDNESDAY, March 31 (HealthDay News) -- Pediatric endocrinologists vary widely in their management of pediatric type 2 diabetes, with younger providers likely managing the disease more aggressively, according to research published in the March issue of Diabetes Care.

Abstract
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Knee Osteoarthritis Patients Often Rely on Self-Help

WEDNESDAY, March 31 (HealthDay News) -- Most patients newly diagnosed with knee osteoarthritis seek medical care, but they also institute lifestyle changes -- often without a physician's advice -- which improve their pain and function levels, according to a study in the April issue of Arthritis Care & Research.

Abstract
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Delayed Intervention Ups Mortality in Coronary Syndrome

WEDNESDAY, March 31 (HealthDay News) -- Patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS) who undergo percutaneous coronary intervention (PCI) within eight hours of clinical presentation have better mortality and cardiac outcomes than those in whom the procedure is delayed, according to a study in the April 6 issue of the Journal of the American College of Cardiology.

Abstract
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Editorial (subscription or payment may be required)

Exercise Improves Insulin Sensitivity in Type 2 Diabetes

WEDNESDAY, March 31 (HealthDay News) -- Patients with type 2 diabetes who undergo exercise training can restore their mitochondrial function and increase insulin sensitivity, according to a study published in the March issue of Diabetes.

Abstract
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Like Men, Uric Acid Levels Linked to Gout in Women

TUESDAY, March 30 (HealthDay News) -- Increasing levels of uric acid are associated with a higher risk of gout in women, although the magnitude of the association is not as great as that seen in men, according to a study in the April issue of Arthritis & Rheumatism.

Abstract
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Eye Disorders Seen in Third of Children With Congenital SNHL

TUESDAY, March 30 (HealthDay News) -- About one-third of children with sensorineural hearing loss (SNHL) have ophthalmologic disorders, which is at the lower end of previously reported rates but still points to a need for ophthalmologic and genetic consultations in patients with the congenital condition, according to research published in the March issue of the Archives of Otolaryngology -- Head & Neck Surgery.

Abstract
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Education Program in Primary Care Can Help Low Back Pain

TUESDAY, March 30 (HealthDay News) -- For patients with low back pain in the primary care setting, the addition of a brief education program on active management to usual care can lead to small improvements in pain, disability, and other measures, according to research published in the March 1 issue of Spine.

Abstract
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'Medical Home' Project Cuts Emergency Room Visits

TUESDAY, March 30 (HealthDay News) -- Children with complex disease are less likely to be taken to the emergency room for treatment if their families are given extra support to organize their children's health care needs, and care is coordinated by one constant source such as a general pediatrician, according to a study published online March 11 in the Journal of Pediatrics.

Abstract
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Telemonitoring Program Beneficial in Type 2 Diabetes

TUESDAY, March 30 (HealthDay News) -- Among individuals with type 2 diabetes and inadequate glycemic control, management with a home telemonitoring program leads to larger reductions in A1C compared to a monthly care coordination phone call, though both improve glycemic control, according to research published in the March issue of Diabetes Care.

Abstract
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Highly Purified Omega-3 Fatty Acid Reduces Rectal Polyps

TUESDAY, March 30 (HealthDay News) -- Eicosapentaenoic acid (EPA), a highly purified form of omega-3 polyunsaturated fatty acid, reduces the number and size of precancerous polyps in subjects with familial adenomatous polyposis (FAP), according to a study published online March 26 in Gut.

Abstract
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Imaging Detects Child Abuse Fractures With High Sensitivity

TUESDAY, March 30 (HealthDay News) -- Positron emission tomography (PET) imaging is likely more sensitive than a skeletal survey in identifying fractures due to child abuse, according to a study in the April issue of Radiology.

Abstract
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In Statin Intolerant, Supplement Found to Lower Cholesterol

TUESDAY, March 30 (HealthDay News) -- Chinese red yeast rice, a dietary supplement made by fermenting the yeast Monascus purpureus over rice, modestly lowers cholesterol in patients intolerant to statins, according to research published in the March 1 issue of the American Journal of Cardiology.

Abstract
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H1N1 Still Circulating, Uptick Seen in Southeastern U.S.

TUESDAY, March 30 (HealthDay News) -- The H1N1 influenza virus is still circulating throughout the United States, and there has even been an uptick in the number of cases in the southeast, health officials said during a March 29 press briefing by the U.S. Centers for Disease Control and Prevention.

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C-Reactive Protein Linked to Cognition in Older Adults

TUESDAY, March 30 (HealthDay News) -- Low-grade inflammation, as measured by high-sensitivity C-reactive protein (hs-CRP), is associated with cerebral microstructural disintegration and poorer performance in executive function in older adults, according to research published in the March 30 issue of Neurology.

Abstract
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Regular Diabetes Screenings Should Start Early

TUESDAY, March 30 (HealthDay News) -- In the United States, initiation of screening for type 2 diabetes between ages 30 and 45, with repeat screenings every three to five years, is cost effective, according to a study published online March 30 in The Lancet.

Abstract
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Diabetes Ups Post-Op Mortality Risk in Cancer Patients

MONDAY, March 29 (HealthDay News) -- Cancer patients with preexisting diabetes have a greater risk of dying after surgery compared to patients without diabetes, according to research published in the April issue of Diabetes Care.

Abstract
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Link Observed Between Pediatric Asthma and GERD

MONDAY, March 29 (HealthDay News) -- In pediatric patients who present with asthma in secondary and tertiary referral settings, there may be an association between asthma and gastroesophageal reflux disease (GERD), but some aspects of the association are unclear, according to a review published online March 29 in Pediatrics.

Abstract
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Colorectal Cancer in Distant Family Can Increase Risk

MONDAY, March 29 (HealthDay News) -- Having a family history of colorectal cancer (CRC) in second- and third-degree relatives can increase an individual's risk of the disease when combined with a first-degree family history, according to research published in the March issue of Gastroenterology.

Abstract
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Study Finds Minority Children Lacking in Vitamin D

MONDAY, March 29 (HealthDay News) -- In the southeastern United States, minority, low-income children have a high prevalence of both 25-hydroxyvitamin D deficiency and insufficiency, with age and season significant predictors of vitamin D deficiency, according to a study published online March 29 in Pediatrics.

Abstract
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Racial and Ethnic Disparities Persist in Pediatric Health Care

MONDAY, March 29 (HealthDay News) -- There are pervasive, persistent and extensive racial/ethnic disparities that occur in every domain of pediatric health and health care, according to a technical report by the American Academy of Pediatrics published online March 29 in Pediatrics.

Abstract
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Antibiotic Reduces Mortality in African AIDS Patients

MONDAY, March 29 (HealthDay News) -- Prophylactic daily administration of the inexpensive and widely-used antibiotic co-trimoxazole among HIV-infected African patients beginning triple-drug antiretroviral therapy improved mortality for up to 72 weeks after the start of treatment, according to a study published online March 29 in The Lancet.

Abstract
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Linaclotide Found Effective for Chronic Constipation

MONDAY, March 29 (HealthDay News) -- In patients with chronic constipation, treatment with linaclotide -- a minimally absorbed peptide agonist of the guanylate cyclase-C receptor -- may be safe and effective, according to a study published in the March issue of Gastroenterology.

Abstract
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Editorial

Anemia Increases Mortality Risk After Heart Attack

MONDAY, March 29 (HealthDay News) -- Anemia increases the risk of death in patients who have had a heart attack and coronary angioplasty, particularly in those with multivessel disease and incomplete revascularization, according to a study in the March 1 issue of the American Journal of Cardiology.

Abstract
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Pulmonary Embolism Diagnosis Mostly in Line With Guidelines

MONDAY, March 29 (HealthDay News) -- Diagnostic imaging tests used for suspected pulmonary embolism are generally in accordance with accepted guidelines, but there is some variation by treating physician specialty and geographic location, according to research published in the April American Journal of Roentgenology.

Abstract
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Breast-Feeding in U.S. Falls Short of National Targets

MONDAY, March 29 (HealthDay News) -- With breast-feeding among non-Hispanic black women lagging well behind Hispanic and non-Hispanic white women, the United States has fallen short of targets for breast-feeding under the Healthy People 2010 (HP2010) health initiative, according to a report in the March 26 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Chest X-Ray Helps Predict Adverse H1N1 Outcomes

MONDAY, March 29 (HealthDay News) -- Abnormal findings on an initial chest X-ray in patients infected with H1N1 influenza, particularly extensive involvement of both lungs, may be associated with a worse prognosis, according to research published in the April issue of Radiology.

Abstract
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Common Signals May Underlie Obesity and Drug Addiction

MONDAY, March 29 (HealthDay News) -- Over-consumption of calorie-rich food may trigger a reaction similar to cocaine and heroin addiction-like responses, according to a study in rats published online March 28 in Nature Neuroscience.

Abstract
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Depth of Infant Head Injury Can Help Identify Cause

MONDAY, March 29 (HealthDay News) -- Head injury depth can be a useful tool to assess the causes and mechanisms of acute cranial trauma in children under 3 years of age, according to a study published online March 29 in Pediatrics.

Abstract
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HPV-Related Oropharyngeal Carcinoma on the Rise

FRIDAY, March 26 (HealthDay News) -- Oropharyngeal squamous cell carcinoma related to human papillomavirus (HPV) represents an emergent, distinct, and increasingly prevalent type of head and neck cancer that may ultimately affect public health policy and clinical practice, according to an editorial published March 25 in BMJ.

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Vitamin D Levels Linked to Pelvic Floor Disorder Risk

FRIDAY, March 26 (HealthDay News) -- Women with higher levels of vitamin D are at lower risk of developing pelvic floor disorders, according to research published in the April issue of Obstetrics & Gynecology.

Abstract
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Giving Emergency Contraception in Advance Found Ineffective

FRIDAY, March 26 (HealthDay News) -- Giving women emergency contraception in advance for use after unprotected sex does not reduce pregnancy rates or lead to changes in contraceptive methods or sexual behavior, according to a review in the March issue of the Cochrane Database of Systematic Reviews.

Abstract
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Diet Plus Weight Control Shown to Improve Cognition

THURSDAY, March 25 (HealthDay News) -- In hypertensive patients who are overweight and obese, combining the Dietary Approaches to Stop Hypertension (DASH) diet with a weight management program may improve neurocognitive function, according to a study published online March 19 in Hypertension. Another Hypertension study, published online March 8, found that perindopril may effectively reduce the risk of major vascular events in patients of any weight category with a history of stroke.

Abstract - Smith
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Abstract - Czernichow
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Four Risk Factors Linked to Life Expectancy Disparities

THURSDAY, March 25 (HealthDay News) -- Four preventable risk factors -- smoking, high blood pressure, elevated blood glucose, and overweight and obesity -- account for a significant proportion of the nation's disparities in life expectancy, according to a study published March 23 in PLoS Medicine.

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Approach May Help Smokers With Weight-Gain Concern

THURSDAY, March 25 (HealthDay News) -- Cognitive behavioral therapy combined with bupropion may be helpful for female smokers who are trying to quit but are concerned about weight gain, according to research published in the March 22 issue of the Archives of Internal Medicine.

Abstract
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Antidepressants Effective in Physically Ill

THURSDAY, March 25 (HealthDay News) -- Antidepressants are more effective than placebo for treating depression in physically ill patients, with results observed within weeks and persisting for months, according to a review in the March issue of the Cochrane Database of Systematic Reviews.

Abstract
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Nearly a Third of 2007 U.S. Infants Delivered by C-Section

THURSDAY, March 25 (HealthDay News) -- Almost a third of births in the United States were cesarean section deliveries in 2007, an increase of 53 percent from 1996 and the highest rate ever reported in the United States, according to the National Center for Health Statistics' March NCHS Data Brief No. 35.

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Reaching Out for Support Tied to Lower Diabetes Mortality Risk

THURSDAY, March 25 (HealthDay News) -- Patients with type 1 and type 2 diabetes who have a propensity to reach out for social support have lower odds of dying compared to their more independent counterparts, according to a study in the March issue of Diabetes Care.

Abstract
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Home Screening for Sexually Transmitted Diseases Popular

THURSDAY, March 25 (HealthDay News) -- Home-screening for sexually transmitted infections is far more popular than going to a clinic for screening, according to a study published in the April issue of Obstetrics & Gynecology.

Abstract
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Aspirin Use in Unexplained Recurrent Miscarriage Studied

WEDNESDAY, March 24 (HealthDay News) -- Among women with unexplained recurrent miscarriage, neither aspirin plus nadroparin nor aspirin monotherapy is likely to improve the live-birth rate compared with placebo, according to a study published online March 24 in the New England Journal of Medicine.

Abstract
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Editorial

Femur Fractures Very Rare With Bisphosphonates

WEDNESDAY, March 24 (HealthDay News) -- The occurrence of subtrochanteric or diaphyseal femur fractures is very rare in women who have used bisphosphonates, even for as long as 10 years, according to an article published online March 24 in the New England Journal of Medicine.

Abstract
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Editorial

Alcohol Pricing Policies Lead to Decreased Consumption

WEDNESDAY, March 24 (HealthDay News) -- Minimum alcohol pricing policies and restrictions on discounting both appear to reduce consumption of alcohol as well as related health care costs, and may target those most at risk of harm from alcohol, according to an English study published online March 24 in The Lancet.

Abstract
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Planning Improves Compliance With End-of-Life Wishes

WEDNESDAY, March 24 (HealthDay News) -- Elderly people who have formal end-of-life planning are more likely to have their wishes followed and their families better prepared than people who do not plan ahead, according to a study published online March 23 in BMJ.

Abstract
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Moderate Alcohol Consumption Seen as Heart Healthy

WEDNESDAY, March 24 (HealthDay News) -- In the general population and in patients with cardiovascular disease, light to moderate alcohol consumption is associated with a lower risk of cardiovascular mortality, according to research published in the March 30 issue of the Journal of the American College of Cardiology.

Abstract - Mukamal
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Abstract - Costanzo
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Editorial (subscription or payment may be required)

Surgery May Be More Beneficial Than Drugs for Esophageal Reflux

WEDNESDAY, March 24 (HealthDay News) -- Surgery improves quality of life and relieves symptoms better than drugs in patients with gastro♠esophageal reflux disease (GERD), at least in the short and medium term, according to a review in the March issue of the Cochrane Database of Systematic Reviews.

Abstract
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Exercise Helps Normal-Weight Women Maintain Weight

TUESDAY, March 23 (HealthDay News) -- Among women consuming a usual diet, about 60 minutes per day of sustained moderate-intensity physical activity is required to maintain normal weight and prevent weight gain, according to a study published in the March 24/31 issue of the Journal of the American Medical Association.

Abstract
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Socioeconomic Status Affects Long-Term Risk of Death

TUESDAY, March 23 (HealthDay News) -- In England, lower socioeconomic status is associated with an increased risk of death, but the risk is largely attenuated after adjustment for health behaviors, according to research published in the March 24/31 issue of the Journal of the American Medical Association.

Abstract
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Complementary Medicine Not Uncommon in Pediatric Cancer

TUESDAY, March 23 (HealthDay News) -- Complementary and alternative medicine (CAM) is often used to treat pediatric patients with cancer, according to a review published online March 22 in Pediatrics.

Abstract
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Stress in Pregnancy May Hike Baby's Asthma Risk

TUESDAY, March 23 (HealthDay News) -- Stresses on a mother during pregnancy may affect the development of her fetus's immune system and increase the risk of the child developing asthma, according to a study published online March 1 in the American Journal of Respiratory and Critical Care Medicine.

Abstract
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Most U.S. Infants Not Getting Enough Daily Vitamin D

TUESDAY, March 23 (HealthDay News) -- Whether fed on breast milk or formula, most U.S. infants do not receive the daily intake of vitamin D recommended by the American Academy of Pediatrics (AAP), according to research published online March 22 in Pediatrics.

Abstract
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FDA Recommends Temporary Suspension of Rotarix Vaccine

MONDAY, March 22 (HealthDay News) -- The U.S. Food and Drug Administration has recommended that health care providers in the United States temporarily suspend use of the rotavirus vaccine Rotarix, manufactured by GlaxoSmithKline, because of possible contamination by an extraneous virus.

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Psychological Health Similar for Young Cancer Survivors, Peers

MONDAY, March 22 (HealthDay News) -- Adolescent and young adult survivors of childhood cancers generally report good psychological adjustment but less positive health beliefs, according to a study published online March 15 in the Journal of Clinical Oncology.

Abstract
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Growth Hormone Beneficial Beyond Increasing Height

MONDAY, March 22 (HealthDay News) -- Growth hormone has additional benefits besides increasing height in children, including improvements in lipid profile and increases in bone mineral density, according to a review published online March 22 in Pediatrics.

Abstract
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Measles Outbreak Linked to Under-Vaccination

MONDAY, March 22 (HealthDay News) -- Intentional under-vaccination of children can lead to measles outbreaks, resulting in significant costs to public health agencies, medical systems, and families, according to research published online March 22 in Pediatrics.

Abstract
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Media May Paint Overly Optimistic Picture of Cancer

MONDAY, March 22 (HealthDay News) -- Coverage of cancer care in the print media may create an overly optimistic view of treatments and outcomes by focusing more often on aggressive treatments and survival than treatment failures and death, according to research published online March 16 in the Archives of Internal Medicine.

Abstract
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Updated Physician Guide on Older Drivers Released

MONDAY, March 22 (HealthDay News) -- To enlist physicians in the effort to reduce the disproportionate rate of fatalities from car accidents among older Americans, the American Medical Association has released the second edition of the Physician's Guide to Assessing and Counseling Older Drivers.

AMA News Release
Physician's Guide to Assessing and Counseling Older Drivers

Hypoglycemia Risk Reduced With Pre-Pregnancy Insulin Therapy

MONDAY, March 22 (HealthDay News) -- Treating women with type 1 diabetes with the insulin analog prandial insulin aspart (IAsp) prior to their becoming pregnant reduces the risk of severe hypoglycemia at every stage of pregnancy, according to a study in the March issue of Diabetes Care.

Abstract
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Extreme Obesity Considerable in Southern California Children

MONDAY, March 22 (HealthDay News) -- More than half a million Southern California children are estimated to be extremely obese, raising the prospect of health problems for the individuals as they age as well as an increasing public health burden, according to a study published online March 22 in the Journal of Pediatrics.

Abstract
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FDA Says High-Dose Simvastatin Ups Myopathy Risk

FRIDAY, March 19 (HealthDay News) -- On March 19, the U.S. Food and Drug Administration notified patients and health care professionals about the potential increased risk of myopathy related to simvastatin (Zocor) 80 mg.

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Benefits of Case Management Seen in Breast Cancer Program

FRIDAY, March 19 (HealthDay News) -- Case management for low-income women who receive free breast cancer screening and diagnostic services may reduce their time to diagnosis, according to research published online March 16 in the Archives of Internal Medicine.

Abstract
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Article Evaluates Options for Non-Motor Parkinson's Issues

FRIDAY, March 19 (HealthDay News) -- Several medications may be helpful in treating such non-motor symptoms of Parkinson's disease as erectile dysfunction and constipation, but there is insufficient evidence for certain treatments for other issues such as anxiety and urinary incontinence, according to an American Academy of Neurology (AAN) practice parameter published in the March 16 issue of Neurology.

Abstract
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Newborn Heart Surgery May Lead to Motor, Cognitive Delays

FRIDAY, March 19 (HealthDay News) -- Babies who undergo heart surgery in early infancy are more likely to experience cognitive and motor delays as very young children, according to a review published online March 15 in Pediatrics.

Abstract
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Low-Fat Diet May Not Reduce Cardio Risks After Menopause

FRIDAY, March 19 (HealthDay News) -- In postmenopausal women, a low-fat diet has little effect on cardiovascular risk factors and no overall effect on coronary heart disease and stroke, according to a study published online Feb. 17 in the American Journal of Clinical Nutrition.

Abstract
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Editorial (subscription or payment may be required)

Carbaglu Approved for Rare Genetic Disorder

THURSDAY, March 18 (HealthDay News) -- The drug Carbaglu (carglumic acid) has been approved by the U.S. Food and Drug Administration to treat a rare genetic disorder called N-acetylglutamate synthase (NAGS deficiency), which results in elevated blood levels of ammonia, the agency said Thursday.

Orphan Europe

Non-Melanoma Skin Cancer Rate Has Risen Greatly

THURSDAY, March 18 (HealthDay News) -- The incidence of non-melanoma skin cancers in the United States has increased dramatically since 1992, and prevalence of a history of skin cancer is much higher than that of other cancers, according to two studies in the March issue of the Archives of Dermatology.

Abstract - Rogers
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Abstract - Stern
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Smoking History Linked to Greater Eye Inflammation Risk

THURSDAY, March 18 (HealthDay News) -- Tobacco smoking history appears to be associated with a higher risk of developing uveitis, according to a study in the March issue of Ophthalmology.

Abstract
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Dipstick for Kidney Disease in Children Not Cost-Effective

THURSDAY, March 18 (HealthDay News) -- For primary care providers, dipstick urinalysis isn't a cost-effective method of screening for chronic kidney disease (CKD) in children, according to research published online March 15 in Pediatrics.

Abstract
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Non-Toxic Lotion Effective Against Lice in Young Children

THURSDAY, March 18 (HealthDay News) -- A nontoxic lotion approved by the U.S. Food and Drug Administration to suffocate lice is very effective in treating head lice in children as young as 6 months old, according to a study published online Feb. 23 in Pediatric Dermatology.

Abstract
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Jaundice Not Linked to Big Increase in First-Year Visits

THURSDAY, March 18 (HealthDay News) -- Infants with jaundice -- whether or not they use inpatient phototherapy -- have only a small increase in first-year outpatient visits, suggesting that these factors play only a little role in so-called "vulnerable child syndrome," according to research published online March 15 in Pediatrics.

Abstract
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Wide Prenatal Screening for Spine Condition Is Costly

THURSDAY, March 18 (HealthDay News) -- It would not be cost-effective to universally screen pregnant women for the neurodegenerative disorder spinal muscular atrophy (SMA) in their fetuses, but screening might make sense for women who have a family history of the disease, according to research published in the March issue of the American Journal of Obstetrics & Gynecology.

Abstract
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Pay-for-Performance Shouldn't Affect Medical Professionalism

THURSDAY, March 18 (HealthDay News) -- Although there are potential conflicts between the attributes of medical professionalism and pay-for-performance, a clash between the two is by no means inevitable, according to an article in the March 16 issue of the Annals of Internal Medicine.

Abstract
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Salsalate May Improve Glycemic Control in Type 2 Diabetes

THURSDAY, March 18 (HealthDay News) -- Salsalate improves markers of glycemic control in patients with type 2 diabetes and may provide a new avenue for the treatment of the disease, subject to further research on the drug's renal and cardiac impact, according to a study in the March 16 issue of the Annals of Internal Medicine.

Abstract
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Diabetes Education Linked to Comprehensive Clinical Care

WEDNESDAY, March 17 (HealthDay News) -- People with diabetes who receive diabetes self-management education (DSME) have a higher likelihood of receiving more comprehensive diabetes clinical care, according to research published in the winter issue of Diabetes Spectrum.

Abstract
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Bilateral Oophorectomy May Do More Harm Than Good

WEDNESDAY, March 17 (HealthDay News) -- The decision to perform prophylactic bilateral oophorectomy at the same time as hysterectomy should be made with caution, as it may do more harm than good, especially in women not at high risk for development of ovarian or breast cancers, according to a review published in the March issue of the Journal of Minimally Invasive Gynecology.

Abstract
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Editorial (subscription or payment may be required)

Mothers' Pesticide Exposure Linked to Deficits in Children

WEDNESDAY, March 17 (HealthDay News) -- Prenatal exposure to pesticides may lead to persistent adverse effects on brain development in children, according to research published online Feb. 25 in Environmental Health Perspectives.

Abstract
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Integrated Care Program Beneficial in Low Back Pain

WEDNESDAY, March 17 (HealthDay News) -- In patients with chronic low back pain, an integrated care program that combines a patient-directed and workplace-directed intervention may significantly reduce disability in private and working life, according to a study published online March 16 in BMJ.

Abstract
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Erectile Dysfunction Predicts Death in High-Risk Patients

TUESDAY, March 16 (HealthDay News) -- In men with cardiovascular disease, erectile dysfunction (ED) is a strong predictor of death, heart attack, stroke, and heart failure, according to a study published online March 15 in Circulation.

Abstract
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Device Provides Sustained Pain Relief for Migraines With Aura

TUESDAY, March 16 (HealthDay News) -- A handheld device that delivers pulses of transcranial magnetic stimulation (TMS) provides sustained pain relief for acute migraines with aura, according to a study published in the April issue of The Lancet Neurology.

Abstract
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Editorial

Household H1N1 Transmission Usually Starts With Children

MONDAY, March 15 (HealthDay News) -- Early in the 2009 outbreak of pandemic H1N1 influenza, household transmission primarily occurred from children to other household members, according to a study in the April issue of Emerging Infectious Diseases.

Full Text

Gastrointestinal Symptoms Linked to Childhood Abuse

MONDAY, March 15 (HealthDay News) -- Children who have been maltreated may be at an increased risk for unexplained gastrointestinal symptoms, and this connection is partly mediated by psychological distress, according to a study in the March/April issue of the Annals of Family Medicine.

Abstract
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Non-Radiologists Account for Increasing Share of PET Scans

MONDAY, March 15 (HealthDay News) -- Since 2002, there has been a disproportionately rapid growth of positron emission tomography (PET) scans performed on units owned or leased by non-radiologists, according to research published in the March issue of the Journal of the American College of Radiology.

Abstract
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Pediatric C. difficile-Related Hospitalizations Increasing

MONDAY, March 15 (HealthDay News) -- In U.S. hospitals, the incidence of Clostridium difficile infection (CDI) in the pediatric population appears to be increasing, according to a study published online ahead of print in the April 4 issue of Emerging Infectious Diseases.

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FDA Adds Boxed Warning to Clopidogrel Label

FRIDAY, March 12 (HealthDay News) -- The U.S. Food and Drug Administration has added a boxed warning to the anti-blood-clotting drug clopidogrel (Plavix) to alert consumers and health care professionals that the drug may be less effective in patients who are unable to metabolize it in order to convert it into its active form.

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Obesity and Alcohol Combined Raise Risk of Liver Disease

FRIDAY, March 12 (HealthDay News) -- Obesity and alcohol act together to increase liver disease risk, an effect seen in both men and women, according to research published online March 11 in BMJ.

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Self-Testing for HPV May Increase Detection Rates

FRIDAY, March 12 (HealthDay News) -- Providing women at high risk for human papillomavirus (HPV) who do not attend regular screening with a kit that allows them to self-collect cervicovaginal samples can help boost the reach of screening programs and the HPV detection rate, according to a study published online March 11 in BMJ.

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Article Outlines Use of PCV13 Vaccine in Young Children

FRIDAY, March 12 (HealthDay News) -- A 13-valent pneumococcal conjugate vaccine was recently licensed by the U.S. Food and Drug Administration and is recommended for all children ages 2 to 59 months, as well as some older children with underlying conditions, according to a report in the March 12 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report. According to another report in the same issue, the vaccine could greatly reduce the prevalence of pneumococcal disease in children younger than 5 years.

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'The Pill' Doesn't Increase Overall Long-Term Mortality Risk

FRIDAY, March 12 (HealthDay News) -- Although women under 45 years of age who are recent oral contraceptive (OC) users are at slightly higher risk of mortality than their non-OC-using counterparts, overall, women who have ever used the pill have significantly lower rates of death, according to a study published online March 11 in BMJ.

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Leptin Shows Advantages Over Insulin in Type 1 Diabetes

FRIDAY, March 12 (HealthDay News) -- The ability of leptin to restore hemoglobin A1c to normal in mice with diabetes (along with its additional benefits relating to body fat and cholesterol) suggests that the hormone may have a role in treating type 1 diabetes mellitus (T1DM) in humans, and may have both short- and long-term advantages over insulin monotherapy, according to research published online March 1 in the Proceedings of the National Academy of Sciences.

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SSRIs Show Anti-Inflammatory Benefit in RA Models

FRIDAY, March 12 (HealthDay News) -- Fluoxetine and citalopram show an anti-inflammatory benefit in rheumatoid arthritis (RA) in laboratory experiments, with findings pointing toward endosomal Toll-like receptors (TLRs) as a target for therapy in the disease, according to research published in the March issue of Arthritis & Rheumatism.

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Coronary Artery Calcium Score Conversion Assessed

FRIDAY, March 12 (HealthDay News) -- Individuals with a coronary calcium (CAC) score of zero likely do not require frequent repeat scanning, as conversion to a score above zero is uncommon before four years, suggesting that a zero score has a four-year "warranty period," according to research published in the March 16 issue of the Journal of the American College of Cardiology.

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Perinatal He

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