Here are what the editors at HealthDay consider to be the most important developments in Urology for November 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Surveillance Reasonable for Low-Risk Prostate Cancer
TUESDAY, Nov. 30 (HealthDay News) -- For men with low-risk, localized prostate cancer, active surveillance appears to be an attractive alternative to initial treatment in terms of quality of life, according to research published in the Dec. 1 issue of the Journal of the American Medical Association.
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Surgeons' Experience Tied to Prostatectomy Outcome
TUESDAY, Nov. 30 (HealthDay News) -- The proportion of surgeons with high annual radical prostatectomy (RP) caseloads has increased over the last decade, and patients undergoing RPs are at lower risk of complications or transfusions if their surgeons are in the high caseload tertile, according to research published in the December issue of The Journal of Urology.
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Novel Model May Surpass Standard for Estimating GFR
MONDAY, Nov. 29 (HealthDay News) -- The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation, which has been proposed to replace the Modification of Diet in Renal Disease (MDRD) for better accuracy, estimates slightly higher glomerular filtration rates and categorizes fewer patients as having stage III or worse chronic kidney disease, according to research published in the November issue of The Journal of Urology.
Axiron Approved as First Underarm Testosterone Drug
WEDNESDAY, Nov. 24 (HealthDay News) -- Axiron has been approved by the U.S. Food and Drug Administration as the first topical testosterone solution to be applied to the underarm, makers Eli Lilly and Acrux said in a news release.
Reallocation of Care Would Increase PCPs' Work Weeks
WEDNESDAY, Nov. 24 (HealthDay News) -- Specialists spend a substantial amount of time providing routine chronic disease follow-up care, and reallocating half of this care to primary care physicians (PCPs) would add a few work weeks for each PCP, according to research published online Oct. 18 in Medical Care.
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Drug Combination May Prevent HIV Acquisition
TUESDAY, Nov. 23 (HealthDay News) -- Taking two oral antiretroviral drugs, emtricitabine and tenofovir disoproxil fumarate (FTC-TDF), once a day may prevent the acquisition of HIV in men who have sex with men, according to a study published online Nov. 23 in the New England Journal of Medicine.
Prostate Cancer Severity No Influence on Recurrence
TUESDAY, Nov. 23 (HealthDay News) -- Practitioners frequently err in determining the severity of prostate cancer, but clinical stage does not appear to influence risk of recurrence after surgical treatment, according to research published online Nov. 22 in Cancer.
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Novel Plastic Circumcision Template Trims Procedure Time
MONDAY, Nov. 22 (HealthDay News) -- Performing adult circumcision using a novel plastic template reduces procedure duration by almost 24 percent and delivers results similar to the standard sleeve procedure, according to a report in the October issue of Urology.
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Testosterone Effects Do Not Last in Frail Elderly Men
FRIDAY, Nov. 19 (HealthDay News) -- Improvements in muscle strength, lean mass, and quality of life (QoL) among frail elderly men during six months of testosterone treatment are not maintained six months after discontinuation of treatment, according to a study published online Nov. 17 in the Journal of Clinical Endocrinology & Metabolism.
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U.S. Health Insurance Compared to 10 Other Nations
FRIDAY, Nov. 19 (HealthDay News) -- Adults in the United States spend more time and money on health insurance than those in many other developed nations, and ultimately deal with more coverage-related disputes and denials, according to research published online Nov. 18 in Health Affairs.
Fraud in Scientific Literature Appears Intentional
THURSDAY, Nov. 18 (HealthDay News) -- Scientific papers retracted after publication due to fraudulent data represent a calculated, deliberate effort to deceive, according to research published online Nov. 15 in the Journal of Medical Ethics.
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DHT Treatment Not Linked to Effect on Prostate Growth
WEDNESDAY, Nov. 17 (HealthDay News) -- The use of dihydrotestosterone (DHT) in older men doesn't appear to have an effect on prostate growth, though it does decrease spinal bone mineral density, according to research published in the Nov. 16 issue of the Annals of Internal Medicine.
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OTC Analgesics Up Risk of Congenital Cryptorchidism
WEDNESDAY, Nov. 17 (HealthDay News) -- Use of over-the-counter pain medication during pregnancy -- particularly in the second trimester -- may increase the risk of congenital cryptorchidism, a finding which may explain recent marked increases in the incidence of this condition, according to research published online Nov. 8 in Human Reproduction.
Men's Knowledge of Testicular Cancer May Be Rising
FRIDAY, Nov. 12 (HealthDay News) -- Compared to a few decades ago, men may be more aware of issues surrounding testis cancer, including symptoms and cure rates, and may be more likely to perform self-examination, according to research published in the October issue of Urology.
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ED in Spinal Stenosis Worsens After Decompression Surgery
FRIDAY, Nov. 12 (HealthDay News) -- Lumbar spinal decompression improves pain and quality of life in patients with lumbar spinal stenosis, but the surgery appears to worsen already high levels of erectile dysfunction (ED) in men with the spine condition, according to a study in the Oct. 15 issue of Spine.
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Physician-Industry Financial Ties Decreased Since 2004
FRIDAY, Nov. 12 (HealthDay News) -- Fewer physicians received drug samples, food and beverages, reimbursement, or payment for professional services in 2009 than in 2004, but a large majority of physicians still report financial relationships with industry, according to research published in the Nov. 8 issue of the Archives of Internal Medicine.
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Androgen Deprivation May Up Risk of Colorectal Cancer
THURSDAY, Nov. 11 (HealthDay News) -- Men taking androgen-deprivation therapy (ADT) for prostate cancer may have a higher risk of colorectal cancer, and that risk appears to increase with longer duration of ADT, according to research published online Nov. 10 in the Journal of the National Cancer Institute.
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Editorial
In Metabolic Syndrome, Microalbuminuria a Risk Marker
THURSDAY, Nov. 4 (HealthDay News) -- The presence of microalbuminuria is an additional marker that can identify a high-risk subset of patients without diabetes who have the metabolic syndrome, according to research published in the Oct. 1 issue of the American Journal of Cardiology.
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Androgen-Deprivation Therapy Linked to Physical Decline
THURSDAY, Nov. 4 (HealthDay News) -- Men with prostate cancer on androgen-deprivation therapy (ADT) do not appear to suffer accelerated cognitive decline but may have diminished physical function and quality of life (QoL), according to a pair of studies published online Nov. 1 in the Journal of Clinical Oncology.
Abstract - Cognitive Function Study
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Abstract - Physical Function Study
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PSA Screening Cuts Prostate Cancer Deaths in Healthy Men
THURSDAY, Nov. 4 (HealthDay News) -- Prostate-specific antigen (PSA) screening in men in good health appears to reduce the risk of prostate cancer-specific mortality (PCSM) with minimal overtreatment, according to a study published online Nov. 1 in the Journal of Clinical Oncology.
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Medicare Act Tied to Reductions in Inappropriate ADT Use
WEDNESDAY, Nov. 3 (HealthDay News) -- Implementation of the Medicare Modernization Act, which led to reduced reimbursement for androgen-deprivation therapy (ADT) for prostate cancer, appears to have substantially reduced the rate at which the therapy is used for inappropriate indications, according to research published in the Nov. 4 issue of the New England Journal of Medicine.
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Very Elderly Women at Risk for Unneeded Catheter Placement
WEDNESDAY, Nov. 3 (HealthDay News) -- Women 80 years of age and older appear to be at high risk for inappropriate urinary catheter (UC) utilization in the emergency department, according to a study published in the November issue of the American Journal of Infection Control.
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