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Category: Endocrinology | Monthly Briefing

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December 2010 Briefing - Diabetes & Endocrinology

Last Updated: January 03, 2011.

 

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for December 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Drug Insurance Coverage Not a Factor in Diabetes Control

THURSDAY, Dec. 30 (HealthDay News) -- Patient demographics, cardiometabolic health, ethnicity, and ongoing drug therapy contribute more to the care gap between patients with type 2 diabetes than access to private drug insurance coverage, according to a study published in the December issue of Diabetes Care.

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Gestational Diabetes Testing Guidelines Updated

THURSDAY, Dec. 30 (HealthDay News) -- In an effort to increase the identification of women with gestational diabetes and reduce health risks to mother and fetus, the American Diabetes Association (ADA) has adopted new guidelines for testing pregnant women for gestational diabetes; these guidelines have been published in a special supplement to the January issue of Diabetes Care.

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Hydroxychloroquine May Be Best in Certain Patients

THURSDAY, Dec. 30 (HealthDay News) -- Hydroxychloroquine (HCQ) initiation is associated with a significant reduction in glycosylated hemoglobin (HbA1c) levels, as compared with methotrexate (MTX) initiation, in patients suffering from both diabetes and rheumatic disease, according to a report published in the December issue of Arthritis & Rheumatism.

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Drinking Linked to Worsened Visual Acuity in Diabetes

TUESDAY, Dec. 28 (HealthDay News) -- Alcohol consumption by individuals with type 2 diabetes is associated with an increased risk for deterioration of visual acuity but not diabetic retinopathy, according to a study in the October issue of Diabetic Medicine.

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Polycystic Ovary Syndrome Tied to Diabetes, Dyslipidemia

TUESDAY, Dec. 28 (HealthDay News) -- Women with polycystic ovary syndrome (PCOS) appear to be at a higher risk of diabetes and dyslipidemia, independent of body mass index (BMI), according to a study published in the January issue of Obstetrics & Gynecology.

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Obesity Causes Delay in Hypoglycemic Effects of Insulin

TUESDAY, Dec. 28 (HealthDay News) -- Hypoglycemic action and absorption of increasing dosages of short-acting insulin are delayed in obese patients with type 2 diabetes, according to a report in the December issue of Diabetes Care.

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Metabolic Syndrome Prevalence High in Psoriasis Patients

TUESDAY, Dec. 28 (HealthDay News) -- The metabolic syndrome occurs substantially more frequently in people with psoriasis than in the general population, according to research published online Dec. 20 in the Archives of Dermatology.

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Contraceptives Linked to Higher Glucose, Insulin Levels

TUESDAY, Dec. 28 (HealthDay News) -- The use of depot medroxyprogesterone acetate appears to be associated with slightly higher levels of fasting glucose and insulin, according to a study in the January issue of Obstetrics & Gynecology.

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Metabolic Syndrome Increases Risk of Hyperuricemia

FRIDAY, Dec. 24 (HealthDay News) -- Patients with metabolic syndrome (MetS) who have hyperuricemia are at increased risk of myocardial infarction (MI) and sudden cardiac death, according to a report published in the Dec. 15 issue of The American Journal of Cardiology.

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FDA Announces Recall of Abbott Glucose Test Strips

WEDNESDAY, Dec. 22 (HealthDay News) -- The U.S. Food and Drug Administration has notified health care professionals and consumers of a recall of 359 lots of Abbott Diabetes Care glucose test strips, as the test strips may give falsely low blood glucose results and negatively impact a patient's health.

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Novel Test Accurately Detects Turner Syndrome

WEDNESDAY, Dec. 22 (HealthDay News) -- A novel, highly sensitive, high-throughput assay approach appears to accurately detect Turner syndrome (TS), according to a study published online Dec. 22 in the Journal of Clinical Endocrinology & Metabolism.

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Diabetes Lowers Women's Long-Term Survival Post-MI

WEDNESDAY, Dec. 22 (HealthDay News) -- Women with diabetes mellitus (DM) have a more than 2.5-fold long-term increased mortality rate after their first myocardial infarction (MI) compared to their counterparts without DM, according to a study published in the Dec. 15 issue of The American Journal of Cardiology.

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Withholding of Thrombolytic Treatment Not Justified

WEDNESDAY, Dec. 22 (HealthDay News) -- Outcomes for patients with diabetes or history of stroke who receive thrombolytic therapy for a new ischemic stroke are better than outcomes for those who do not receive thrombolytic therapy, according to a report in the December issue of Diabetes Care.

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Web-Based Shared Medical Records Useful for Sick Patients

WEDNESDAY, Dec. 22 (HealthDay News) -- Web-based shared medical records (SMR) may provide an effective way for physicians to conduct non-visit-based health care, specifically for older individuals with diabetes, according to a report published in the November issue of Diabetes Care.

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Fatty Acid Tied to Lower Diabetes and Dyslipidemia Risk

TUESDAY, Dec. 21 (HealthDay News) -- Higher levels of circulating trans-palmitoleate, which may result from consumption of whole-fat dairy products, appear to be associated with lower insulin resistance, dyslipidemia, and incident diabetes, according to a study in the Dec. 21 issue of the Annals of Internal Medicine.

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Corticosteroid Use May Increase Risk of Diabetes

TUESDAY, Dec. 21 (HealthDay News) -- The use of inhaled corticosteroids among patients with respiratory disease appears to be associated with modest increases in the risk of diabetes onset and progression, according to a study published in the November issue of The American Journal of Medicine.

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Aliskiren Reduces Renal Disease in Diabetes Patients

MONDAY, Dec. 20 (HealthDay News) -- When aliskiren is added to losartan it reduces albuminuria and renal dysfunction and is well tolerated in patients with type 2 diabetes, hypertension, and nephropathy, according to a report published in the November issue of Diabetes Care.

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Lifestyle Intervention Improves Health for Diabetes Patients

FRIDAY, Dec. 17 (HealthDay News) -- Lifestyle intervention for weight loss in obese individuals with diabetes may reduce high-sensitivity C-reactive protein (hs-CRP) levels, according to a report published in the November issue of Diabetes Care.

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Study Explores Cardiac Issues in People With Type 2 Diabetes

FRIDAY, Dec. 17 (HealthDay News) -- Diastolic dysfunction found in type 2 diabetes may be associated with both regional signs of sympathetic integrity and clinical evidence of autonomic neuropathy, according to research published in the December issue of the Journal of the American College of Cardiology: Cardiovascular Imaging.

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Statement Stresses Importance of Exercise in Diabetes

FRIDAY, Dec. 17 (HealthDay News) -- People who engage in regular physical activity (PA) may reduce their risk for developing type 2 diabetes mellitus (T2DM), and people with T2DM may reduce symptoms and complications and increase quality of life by participating in regular PA, according to a statement published in the December issue of Medicine & Science in Sports & Exercise.

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Sweet Drinks May Lead to Metabolic Syndrome, Type 2 DM

THURSDAY, Dec. 16 (HealthDay News) -- Higher consumption of sugar-sweetened beverages (SSBs) is associated with development of metabolic syndrome and type 2 diabetes, according to research published in the November issue of Diabetes Care.

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Long-Term Antidepressant Use May Increase Type 2 DM Risk

THURSDAY, Dec. 16 (HealthDay News) -- When people at risk for type 2 diabetes use antidepressants long term they may be more likely to develop type 2 diabetes, although metformin may protect against this, according to a study published in the December issue of Diabetes Care.

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Metabolic Syndrome Linked to Occupation

THURSDAY, Dec. 16 (HealthDay News) -- Transportation workers and farm managers are among the occupational groups with the greatest risk for developing metabolic syndrome, according to research published in the November issue of Diabetes Care.

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Walking Linked to Improved Metabolic Control in Type 2 DM

WEDNESDAY, Dec. 15 (HealthDay News) -- Patients with diabetes who walk with a trainer may improve their A1C score, need fewer medications, and improve their fasting blood glucose levels, according to a study published in the November issue of Diabetes Care.

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Vitamin D Levels Moderately Tied to Frailty Risk

WEDNESDAY, Dec. 15 (HealthDay News) -- Low and elevated 25-hydroxyvitamin D (25[OH]D) levels appear to be moderately associated with a higher risk of frailty among older women, with lower 25(OH)D levels among non-frail women modestly associated with an elevated risk of incident frailty or death within a few years, according to a study published in the December issue of the Journal of Clinical Endocrinology & Metabolism.

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Mutations Associated With Adrenal Gland Tumors ID'd

TUESDAY, Dec. 14 (HealthDay News) -- Researchers have uncovered genetic variations associated with a type of tumor found in the adrenal gland, and their findings have been published in the Dec. 15 issue of the Journal of the American Medical Association.

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Healthy Diet Tied to Reversion of Metabolic Syndrome

TUESDAY, Dec. 14 (HealthDay News) -- Patients who adhere to a healthy diet may be able to reverse metabolic syndrome (MetS), according to a study published in the November issue of Diabetes Care.

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Resistance Exercise Improves Sugar Levels in Gestational DM

FRIDAY, Dec. 10 (HealthDay News) -- Women with gestational diabetes mellitus (GDM) who perform resistance exercises during pregnancy may have better capillary glycemic levels and be less likely to require insulin coverage, according to a study in the December issue of the American Journal of Obstetrics & Gynecology.

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Many Youths With Diabetes Smoke Cigarettes

THURSDAY, Dec. 9 (HealthDay News) -- High proportions of youths with types 1 or 2 diabetes mellitus use tobacco, which adds to their already elevated risk for developing cardiovascular disease, according to a study published online Dec. 6 in the Journal of Pediatrics.

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High Normal Glucose Levels Tied to Cardiovascular Risk

MONDAY, Dec. 6 (HealthDay News) -- Fasting glucose levels on the higher end of normal are associated with increased cardiovascular risk, though the relationship appears to be caused by other conventional risk factors, according to a study published in the Dec. 1 issue of The American Journal of Cardiology.

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Primary Ovarian Insufficiency Tied to Depression Risk

MONDAY, Dec. 6 (HealthDay News) -- Women with primary ovarian insufficiency (POI) appear to be at an increased lifetime risk for major depression, according to a study published online Nov. 3 in the Journal of Clinical Endocrinology & Metabolism.

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Glycemia Level Linked to SNP Effects on Insulin

FRIDAY, Dec. 3 (HealthDay News) -- For the genes TCF7L2 and WFS1 -- which play a role in impaired incretin signaling -- glycemic levels determine the effects of single nucleotide polymorphisms (SNPs) on insulin secretion, according to research published in the December issue of Diabetes.

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Factors Appear Useful in Predicting Gestational Diabetes

FRIDAY, Dec. 3 (HealthDay News) -- Several easily measured demographic and clinical factors, along with two biochemical values, can be used for predicting gestational diabetes mellitus (GDM) in women in their first trimester of pregnancy, according to research published in the December issue of Diabetes.

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Fecal Bacteria Post-RYGB Reflect Metabolic Change

FRIDAY, Dec. 3 (HealthDay News) -- Intestinal microbiology rapidly changes after Roux-en-Y gastric bypass (RYGB), adapting to the starvation-like environment, with increases in some bacteria reflecting decreasing obesity-related inflammation and some changes differing by diabetes status, according to research published in the December issue of Diabetes.

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GLP-1 Analog Liraglutide Found to Delay Diabetes in Rats

THURSDAY, Dec. 2 (HealthDay News) -- In a rat model of type 2 diabetes, treatment with the glucagon-like peptide-1 analog liraglutide delays the development of the disease due to factors such as lower energy intake and body weight and improved insulin sensitivity, according to research published in the October issue of Diabetes.

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Diabetes Alters Brain Cholesterol Metabolism in Mice

THURSDAY, Dec. 2 (HealthDay News) -- Diabetes and insulin can alter brain cholesterol metabolism, a fact that may play a key role in the neurologic and metabolic dysfunction in diabetes patients, according to a mouse study published in the Dec. 1 issue of Cell Metabolism.

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Burnout Driving Away Many Emergency Physicians

THURSDAY, Dec. 2 (HealthDay News) -- Conflicts between work and family and poor on-the-job teamwork contribute to burnout and drive many physicians, particularly emergency physicians, to want to leave their profession, according to a study published online Dec. 1 in the Emergency Medicine Journal.

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All-Cause Mortality Lowest With BMI of 20 to 24.9

WEDNESDAY, Dec. 1 (HealthDay News) -- All-cause mortality is lowest for adults with a body mass index (BMI) of 20.0 to 24.9 kg/m², and the risk is more than doubled for those who are extremely obese, according to research published in the Dec. 1 issue of the New England Journal of Medicine.

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Sleeping Problems Associated With Metabolic Syndrome

WEDNESDAY, Dec. 1 (HealthDay News) -- People who have trouble sleeping, particularly those with loud snoring, may be at increased risk for developing metabolic syndrome, according to research published in the Dec. 1 issue of SLEEP.

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